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Protein

Luminal-binding protein 8

Gene

BIP8

Organism
Nicotiana tabacum (Common tobacco)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.

GO - Molecular functioni

Keywordsi

LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Luminal-binding protein 8
Short name:
BiP 8
Alternative name(s):
78 kDa glucose-regulated protein homolog 8
Short name:
GRP-78-8
Gene namesi
Name:BIP8
OrganismiNicotiana tabacum (Common tobacco)
Taxonomic identifieri4097 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana
Proteomesi
  • UP000084051 Componenti: Genome assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Endoplasmic reticulum

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000078669‹1 – 293Luminal-binding protein 8Add BLAST›293

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi244N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiQ03686

Structurei

3D structure databases

ProteinModelPortaliQ03686
SMRiQ03686
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi290 – 293Prevents secretion from ERPROSITE-ProRule annotation4

Sequence similaritiesi

Belongs to the heat shock protein 70 family.Curated

Family and domain databases

Gene3Di1.20.1270.10, 1 hit
2.60.34.10, 1 hit
InterProiView protein in InterPro
IPR029048 HSP70_C_sf
IPR029047 HSP70_peptide-bd_sf
IPR013126 Hsp_70_fam
PANTHERiPTHR19375 PTHR19375, 1 hit
PfamiView protein in Pfam
PF00012 HSP70, 1 hit
PRINTSiPR00301 HEATSHOCK70
SUPFAMiSSF100920 SSF100920, 1 hit
SSF100934 SSF100934, 1 hit
PROSITEiView protein in PROSITE
PS00014 ER_TARGET, 1 hit

Sequencei

Sequence statusi: Fragment.

Q03686-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
RIPKVQQLLK DYFDGKEPNK GVNPDEAVAY GAAVQGGILS GEGGDETKDI
60 70 80 90 100
LLLDVAPLTL GIETVGGVMT KLIPRNTVIP SKKSQVFTTY QDQQTTVTIQ
110 120 130 140 150
VFEGERSLTK DCRLLGKFDL TGIAPAPRGT PQIEVTFEVD ANGILNVKAE
160 170 180 190 200
DKASGKSEKI TITNDKGRLS QEEIERMVKE AEEFAEEDKK VKERIDARNS
210 220 230 240 250
LETYVYNMRN QINDKDKLAD KLESDEKEKI ETATKEALEW LDDNQSAEKE
260 270 280 290
DYEEKLKEVE AVCNPIITAV YQKSGGAPGG ESGASEDDDH DEL
Length:293
Mass (Da):32,342
Last modified:February 1, 1995 - v1
Checksum:i44939595E45650E6
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei11

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X60062 mRNA Translation: CAA42664.1
PIRiS21881
UniGeneiNta.3075

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X60062 mRNA Translation: CAA42664.1
PIRiS21881
UniGeneiNta.3075

3D structure databases

ProteinModelPortaliQ03686
SMRiQ03686
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ03686

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di1.20.1270.10, 1 hit
2.60.34.10, 1 hit
InterProiView protein in InterPro
IPR029048 HSP70_C_sf
IPR029047 HSP70_peptide-bd_sf
IPR013126 Hsp_70_fam
PANTHERiPTHR19375 PTHR19375, 1 hit
PfamiView protein in Pfam
PF00012 HSP70, 1 hit
PRINTSiPR00301 HEATSHOCK70
SUPFAMiSSF100920 SSF100920, 1 hit
SSF100934 SSF100934, 1 hit
PROSITEiView protein in PROSITE
PS00014 ER_TARGET, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiBIP8_TOBAC
AccessioniPrimary (citable) accession number: Q03686
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: February 28, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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