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Entry version 133 (02 Jun 2021)
Sequence version 1 (01 Nov 1996)
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Protein

Peroxisomal membrane protein PEX29

Gene

PEX29

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in the regulation of peroxisome number, size and distribution.

1 Publication

Miscellaneous

Present with 5040 molecules/cell.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processPeroxisome biogenesis

Protein family/group databases

Transport Classification Database

More...
TCDBi
3.A.20.1.5, the peroxisomal protein importer (ppi) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Peroxisomal membrane protein PEX29
Alternative name(s):
Peroxin-29
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PEX29
Ordered Locus Names:YDR479C
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome IV

Organism-specific databases

Saccharomyces Genome Database

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SGDi
S000002887, PEX29

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
FungiDB:YDR479C

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 145CytoplasmicSequence analysisAdd BLAST145
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei146 – 166HelicalSequence analysisAdd BLAST21
Topological domaini167 – 172PeroxisomalSequence analysis6
Transmembranei173 – 193HelicalSequence analysisAdd BLAST21
Topological domaini194 – 264CytoplasmicSequence analysisAdd BLAST71
Transmembranei265 – 285HelicalSequence analysisAdd BLAST21
Topological domaini286 – 287PeroxisomalSequence analysis2
Transmembranei288 – 308HelicalSequence analysisAdd BLAST21
Topological domaini309 – 554CytoplasmicSequence analysisAdd BLAST246

Keywords - Cellular componenti

Membrane, Peroxisome

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002522691 – 554Peroxisomal membrane protein PEX29Add BLAST554

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q03370

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q03370

PRoteomics IDEntifications database

More...
PRIDEi
Q03370

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q03370

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
32531, 163 interactors

Database of interacting proteins

More...
DIPi
DIP-5175N

Protein interaction database and analysis system

More...
IntActi
Q03370, 42 interactors

Molecular INTeraction database

More...
MINTi
Q03370

STRING: functional protein association networks

More...
STRINGi
4932.YDR479C

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q03370, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni11 – 73DisorderedSequence analysisAdd BLAST63
Regioni500 – 532DisorderedSequence analysisAdd BLAST33

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi11 – 26Polar residuesSequence analysisAdd BLAST16
Compositional biasi35 – 73Polar residuesSequence analysisAdd BLAST39

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the PEX28-32 family. PEX29 subfamily.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QQTF, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_023118_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q03370

Identification of Orthologs from Complete Genome Data

More...
OMAi
GTRFFED

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR010482, Peroxin

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06398, Pex24p, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q03370-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDSVTNFFWN DTYNAGTPTR STLKGKKVQN GIDGKSQAKK ESISSGSRTS
60 70 80 90 100
DPTRGSLPSS SGQPTSGGGF PSTSNIQKMM ADTLVEKIIK MALPPSSKTA
110 120 130 140 150
VDTIHHRMVA GKERPKLSVQ ITSRNFIQMN SRLGVPFMIM DELIKILNWT
160 170 180 190 200
NPAYTVSIMF LYTLIILKPF QMLSSLPIFY LLFCVMVPQY LYIHKPNPTS
210 220 230 240 250
YLDNNQTPAQ GPPLRRPEVP KPVPELSQEF VLNLTDLQNH MLLYVKFYDF
260 270 280 290 300
TLLILQKFAF FTNEAISSFY FIVLLIIATL NFLYMDKFIK LIPMRPVLIL
310 320 330 340 350
LGWGFFIASH PSNREYLLTK LNSEETRLKT LTISTNLESK ILQHLKLIEA
360 370 380 390 400
REHRLVMIFE IQKYLPEYKE WRPVGFSDDD YSLFSSLRIY QRRIEENSVK
410 420 430 440 450
SLEEIEPPKD WEWEANSHWV LDLDPKEWVE DEFIQYVEID SETKWVYDLN
460 470 480 490 500
LDGQRGSYRR RMWTNSCVRK KLDSGISSNL GEEEVVNPLR EETYRQGVHG
510 520 530 540 550
VTKGSMSGGL THSSDDDRAD EESINGTIPN LNNIDADASY PSIEELTDTL

NSTI
Length:554
Mass (Da):63,543
Last modified:November 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC2EB849C36FB69EB
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U33050 Genomic DNA Translation: AAB64918.1
BK006938 Genomic DNA Translation: DAA12312.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S69646

NCBI Reference Sequences

More...
RefSeqi
NP_010767.1, NM_001180787.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
YDR479C_mRNA; YDR479C; YDR479C

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
852090

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sce:YDR479C

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U33050 Genomic DNA Translation: AAB64918.1
BK006938 Genomic DNA Translation: DAA12312.1
PIRiS69646
RefSeqiNP_010767.1, NM_001180787.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi32531, 163 interactors
DIPiDIP-5175N
IntActiQ03370, 42 interactors
MINTiQ03370
STRINGi4932.YDR479C

Protein family/group databases

TCDBi3.A.20.1.5, the peroxisomal protein importer (ppi) family

PTM databases

iPTMnetiQ03370

Proteomic databases

MaxQBiQ03370
PaxDbiQ03370
PRIDEiQ03370

Genome annotation databases

EnsemblFungiiYDR479C_mRNA; YDR479C; YDR479C
GeneIDi852090
KEGGisce:YDR479C

Organism-specific databases

SGDiS000002887, PEX29
VEuPathDBiFungiDB:YDR479C

Phylogenomic databases

eggNOGiENOG502QQTF, Eukaryota
HOGENOMiCLU_023118_1_0_1
InParanoidiQ03370
OMAiGTRFFED

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q03370
RNActiQ03370, protein

Family and domain databases

InterProiView protein in InterPro
IPR010482, Peroxin
PfamiView protein in Pfam
PF06398, Pex24p, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPEX29_YEAST
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q03370
Secondary accession number(s): D6VTA2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: November 1, 1996
Last modified: June 2, 2021
This is version 133 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families
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