UniProtKB - Q03351 (NTRK3_RAT)
NT-3 growth factor receptor
Ntrk3
Functioni
Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation (By similarity).
NTRK3 isoforms containing insertions within the kinase domain can autophosphorylate in response to NTF3/neurotrophin-3, but cannot mediate downstream phenotypic responses (PubMed:8494647, PubMed:8494648).
By similarity2 PublicationsCatalytic activityi
- EC:2.7.10.1PROSITE-ProRule annotation
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 572 | ATPPROSITE-ProRule annotation | 1 | |
Active sitei | 679 | Proton acceptorPROSITE-ProRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 544 – 552 | ATPPROSITE-ProRule annotation | 9 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- GPI-linked ephrin receptor activity Source: BHF-UCL
- neurotrophin binding Source: GO_Central
- neurotrophin receptor activity Source: RGD
- p53 binding Source: RGD
- protein serine/threonine/tyrosine kinase activity Source: RHEA
- transmembrane receptor protein serine/threonine kinase activity Source: Reactome
- transmembrane receptor protein tyrosine kinase activity Source: GO_Central
GO - Biological processi
- activation of GTPase activity Source: RGD
- activation of protein kinase B activity Source: RGD
- cellular response to nerve growth factor stimulus Source: GO_Central
- cellular response to retinoic acid Source: RGD
- circadian rhythm Source: RGD
- cochlea development Source: RGD
- heart development Source: UniProtKB
- lens fiber cell differentiation Source: RGD
- mechanoreceptor differentiation Source: RGD
- modulation by virus of host transcription Source: RGD
- myelination in peripheral nervous system Source: RGD
- negative regulation of astrocyte differentiation Source: RGD
- negative regulation of cell death Source: RGD
- negative regulation of protein phosphorylation Source: RGD
- neuronal action potential propagation Source: RGD
- neuron fate specification Source: RGD
- neuron migration Source: RGD
- positive regulation of actin cytoskeleton reorganization Source: RGD
- positive regulation of apoptotic process Source: RGD
- positive regulation of axon extension involved in regeneration Source: RGD
- positive regulation of cell migration Source: RGD
- positive regulation of cell population proliferation Source: RGD
- positive regulation of gene expression Source: RGD
- positive regulation of kinase activity Source: GO_Central
- positive regulation of MAPK cascade Source: GO_Central
- positive regulation of MAP kinase activity Source: RGD
- positive regulation of neuron projection development Source: RGD
- positive regulation of peptidyl-serine phosphorylation Source: RGD
- positive regulation of phosphatidylinositol 3-kinase signaling Source: GO_Central
- positive regulation of positive chemotaxis Source: RGD
- positive regulation of synapse assembly Source: RGD
- regulation of postsynaptic density assembly Source: SynGO
- regulation of presynapse assembly Source: SynGO
- regulation of protein kinase B signaling Source: GO_Central
- response to axon injury Source: RGD
- response to corticosterone Source: RGD
- response to ethanol Source: RGD
- transmembrane receptor protein tyrosine kinase signaling pathway Source: RGD
Keywordsi
Molecular function | Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase |
Biological process | Differentiation, Neurogenesis |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
BRENDAi | 2.7.10.1, 5301 |
Reactomei | R-RNO-388844, Receptor-type tyrosine-protein phosphatases R-RNO-9034013, NTF3 activates NTRK3 signaling R-RNO-9034793, Activated NTRK3 signals through PLCG1 R-RNO-9603381, Activated NTRK3 signals through PI3K |
Names & Taxonomyi
Protein namesi | Recommended name: NT-3 growth factor receptor (EC:2.7.10.1)Alternative name(s): GP145-TrkC Short name: Trk-C Neurotrophic tyrosine kinase receptor type 3 TrkC tyrosine kinase |
Gene namesi | Name:Ntrk3 Synonyms:Trkc |
Organismi | Rattus norvegicus (Rat) |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 3214, Ntrk3 |
Subcellular locationi
Other locations
Golgi apparatus
- Golgi membrane Source: Reactome
Plasma Membrane
- integral component of plasma membrane Source: GO_Central
- integral component of postsynaptic membrane Source: SynGO
- plasma membrane Source: RGD
Other locations
- axon Source: GO_Central
- cytoplasm Source: RGD
- glutamatergic synapse Source: SynGO
- membrane Source: RGD
- receptor complex Source: RGD
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 32 – 429 | ExtracellularSequence analysisAdd BLAST | 398 | |
Transmembranei | 430 – 453 | HelicalSequence analysisAdd BLAST | 24 | |
Topological domaini | 454 – 864 | CytoplasmicSequence analysisAdd BLAST | 411 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 31 | By similarityAdd BLAST | 31 | |
ChainiPRO_0000016735 | 32 – 864 | NT-3 growth factor receptorAdd BLAST | 833 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 32 ↔ 38 | By similarity | ||
Disulfide bondi | 36 ↔ 45 | By similarity | ||
Glycosylationi | 68 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 72 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 79 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 133 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 163 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 164 ↔ 189 | By similarity | ||
Disulfide bondi | 166 ↔ 207 | By similarity | ||
Glycosylationi | 203 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 218 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 231 ↔ 284 | By similarity | ||
Glycosylationi | 232 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 259 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 267 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 272 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 294 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 320 ↔ 362 | PROSITE-ProRule annotation | ||
Glycosylationi | 375 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 388 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Modified residuei | 493 | PhosphoserineBy similarity | 1 | |
Modified residuei | 516 | Phosphotyrosine; by autocatalysisBy similarity | 1 | |
Modified residuei | 705 | Phosphotyrosine; by autocatalysisBy similarity | 1 | |
Modified residuei | 709 | Phosphotyrosine; by autocatalysisBy similarity | 1 | |
Modified residuei | 710 | Phosphotyrosine; by autocatalysisBy similarity | 1 | |
Modified residuei | 859 | Phosphotyrosine; by autocatalysisBy similarity | 1 |
Post-translational modificationi
Keywords - PTMi
Disulfide bond, Glycoprotein, PhosphoproteinProteomic databases
PaxDbi | Q03351 |
PTM databases
GlyGeni | Q03351, 14 sites |
iPTMneti | Q03351 |
PhosphoSitePlusi | Q03351 |
Expressioni
Tissue specificityi
Gene expression databases
Bgeei | ENSRNOG00000018674, Expressed in frontal cortex and 21 other tissues |
ExpressionAtlasi | Q03351, baseline and differential |
Genevisiblei | Q03351, RN |
Interactioni
Subunit structurei
Exists in a dynamic equilibrium between monomeric (low affinity) and dimeric (high affinity) structures (By similarity). Binds SH2B2 (PubMed:9856458).
Interacts with SQSTM1 and KIDINS220 (PubMed:12471037, PubMed:15167895).
Interacts with PTPRS (PubMed:17967490).
Interacts with MAPK8IP3/JIP3 (PubMed:21775604).
By similarity5 PublicationsSites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sitei | 516 | Interaction with SHC1By similarity | 1 | |
Sitei | 859 | Interaction with PLC-gamma-1By similarity | 1 |
Binary interactionsi
Q03351
With | #Exp. | IntAct |
---|---|---|
Cdk5 [Q03114] | 2 | EBI-7365348,EBI-2008531 |
GO - Molecular functioni
- neurotrophin binding Source: GO_Central
- p53 binding Source: RGD
Protein-protein interaction databases
BioGRIDi | 248241, 7 interactors |
DIPi | DIP-5718N |
IntActi | Q03351, 4 interactors |
MINTi | Q03351 |
STRINGi | 10116.ENSRNOP00000044402 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 104 – 125 | LRR 1Add BLAST | 22 | |
Repeati | 128 – 149 | LRR 2Add BLAST | 22 | |
Domaini | 160 – 209 | LRRCTAdd BLAST | 50 | |
Domaini | 210 – 300 | Ig-like C2-type 1Add BLAST | 91 | |
Domaini | 309 – 382 | Ig-like C2-type 2Add BLAST | 74 | |
Domaini | 538 – 853 | Protein kinasePROSITE-ProRule annotationAdd BLAST | 316 |
Sequence similaritiesi
Keywords - Domaini
Immunoglobulin domain, Leucine-rich repeat, Repeat, Signal, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG1026, Eukaryota |
GeneTreei | ENSGT00940000155645 |
HOGENOMi | CLU_000288_74_1_1 |
InParanoidi | Q03351 |
OMAi | RXVGGHT |
OrthoDBi | 295510at2759 |
PhylomeDBi | Q03351 |
TreeFami | TF106465 |
Family and domain databases
Gene3Di | 2.60.40.10, 2 hits 3.80.10.10, 1 hit |
InterProi | View protein in InterPro IPR000483, Cys-rich_flank_reg_C IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR013098, Ig_I-set IPR003599, Ig_sub IPR013151, Immunoglobulin IPR011009, Kinase-like_dom_sf IPR001611, Leu-rich_rpt IPR032675, LRR_dom_sf IPR000372, LRRNT IPR020777, NTRK IPR020446, NTRK3 IPR031635, NTRK_LRRCT IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR001245, Ser-Thr/Tyr_kinase_cat_dom IPR008266, Tyr_kinase_AS IPR020635, Tyr_kinase_cat_dom IPR002011, Tyr_kinase_rcpt_2_CS |
Pfami | View protein in Pfam PF07679, I-set, 1 hit PF00047, ig, 1 hit PF13855, LRR_8, 1 hit PF16920, LRRCT_2, 1 hit PF01462, LRRNT, 1 hit PF07714, PK_Tyr_Ser-Thr, 2 hits |
PRINTSi | PR01939, NTKRECEPTOR PR01942, NTKRECEPTOR3 PR00109, TYRKINASE |
SMARTi | View protein in SMART SM00409, IG, 1 hit SM00082, LRRCT, 1 hit SM00013, LRRNT, 1 hit SM00219, TyrKc, 1 hit |
SUPFAMi | SSF48726, SSF48726, 2 hits SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 1 hit PS51450, LRR, 1 hit PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00109, PROTEIN_KINASE_TYR, 1 hit PS00239, RECEPTOR_TYR_KIN_II, 1 hit |
s (8)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry describes 8 produced by isoformsialternative splicing. AlignAdd to basketThis isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MDVSLCPAKC SFWRIFLLGS VWLDYVGSVL ACPANCVCSK TEINCRRPDD
60 70 80 90 100
GNLFPLLEGQ DSGNSNGNAS INITDISRNI TSIHIENWRG LHTLNAVDME
110 120 130 140 150
LYTGLQKLTI KNSGLRNIQP RAFAKNPHLR YINLSSNRLT TLSWQLFQTL
160 170 180 190 200
SLRELRLEQN FFNCSCDIRW MQLWQEQGEA RLDSQSLYCI SADGSQLPLF
210 220 230 240 250
RMNISQCDLP EISVSHVNLT VREGDNAVIT CNGSGSPLPD VDWIVTGLQS
260 270 280 290 300
INTHQTNLNW TNVHAINLTL VNVTSEDNGF TLTCIAENVV GMSNASVALT
310 320 330 340 350
VYYPPRVVSL VEPEVRLEHC IEFVVRGNPT PTLHWLYNGQ PLRESKIIHM
360 370 380 390 400
DYYQEGEVSE GCLLFNKPTH YNNGNYTLIA KNALGTANQT INGHFLKEPF
410 420 430 440 450
PESTDFFDFE SDASPTPPIT VTHKPEEDTF GVSIAVGLAA FACVLLVVLF
460 470 480 490 500
IMINKYGRRS KFGMKGPVAV ISGEEDSASP LHHINHGITT PSSLDAGPDT
510 520 530 540 550
VVIGMTRIPV IENPQYFRQG HNCHKPDTYV QHIKRRDIVL KRELGEGAFG
560 570 580 590 600
KVFLAECYNL SPTKDKMLVA VKALKDPTLA ARKDFQREAE LLTNLQHEHI
610 620 630 640 650
VKFYGVCGDG DPLIMVFEYM KHGDLNKFLR AHGPDAMILV DGQPRQAKGE
660 670 680 690 700
LGLSQMLHIA SQIASGMVYL ASQHFVHRDL ATRNCLVGAN LLVKIGDFGM
710 720 730 740 750
SRDVYSTDYY REGPYQKGPF SVSWQQQRLA ASAASTLFNP SGNDFCIWCE
760 770 780 790 800
VGGHTMLPIR WMPPESIMYR KFTTESDVWS FGVILWEIFT YGKQPWFQLS
810 820 830 840 850
NTEVIECITQ GRVLERPRVC PKEVYDVMLG CWQREPQQRL NIKEIYKILH
860
ALGKATPIYL DILG
The sequence of this isoform differs from the canonical sequence as follows:
712-736: Missing.
737-750: Missing.
The sequence of this isoform differs from the canonical sequence as follows:
712-736: Missing.
The sequence of this isoform differs from the canonical sequence as follows:
737-750: Missing.
The sequence of this isoform differs from the canonical sequence as follows:
529-612: YVQHIKRRDI...FYGVCGDGDP → WVFSNIDNHG...VYFSKGRHGF
613-864: Missing.
The sequence of this isoform differs from the canonical sequence as follows:
529-597: YVQHIKRRDI...EAELLTNLQH → WVFSNIDNHG...LPLPVLILKT
598-864: Missing.
The sequence of this isoform differs from the canonical sequence as follows:
529-567: YVQHIKRRDI...YNLSPTKDKM → CFREIMLNPI...VYFSKGRHGF
568-864: Missing.
The sequence of this isoform differs from the canonical sequence as follows:
529-562: YVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSP → FGRIEGFAYGKRYVVMTSVHCHPCWFRFGGLEWL
563-864: Missing.
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_002934 | 529 – 612 | YVQHI…GDGDP → WVFSNIDNHGILNLKDNRDH LVPSTHYIYEEPEVQSGDVS YPRSHGFREIMLNPISLSGH SKPLNHGIYVEDVNVYFSKG RHGF in isoform IC158. CuratedAdd BLAST | 84 | |
Alternative sequenceiVSP_002932 | 529 – 597 | YVQHI…TNLQH → WVFSNIDNHGILNLKDNRDH LVPSTHYIYEEPEVQSGDVS YPRSHGELLPLTSLYEVKPL PLPVLILKT in isoform IC143. CuratedAdd BLAST | 69 | |
Alternative sequenceiVSP_002930 | 529 – 567 | YVQHI…TKDKM → CFREIMLNPISLSGHSKPLN HGIYVEDVNVYFSKGRHGF in isoform IC113. CuratedAdd BLAST | 39 | |
Alternative sequenceiVSP_002928 | 529 – 562 | YVQHI…YNLSP → FGRIEGFAYGKRYVVMTSVH CHPCWFRFGGLEWL in isoform IC108. CuratedAdd BLAST | 34 | |
Alternative sequenceiVSP_002929 | 563 – 864 | Missing in isoform IC108. CuratedAdd BLAST | 302 | |
Alternative sequenceiVSP_002931 | 568 – 864 | Missing in isoform IC113. CuratedAdd BLAST | 297 | |
Alternative sequenceiVSP_002933 | 598 – 864 | Missing in isoform IC143. CuratedAdd BLAST | 267 | |
Alternative sequenceiVSP_002935 | 613 – 864 | Missing in isoform IC158. CuratedAdd BLAST | 252 | |
Alternative sequenceiVSP_002936 | 712 – 736 | Missing in isoform KI14 and isoform TRKC. 1 PublicationAdd BLAST | 25 | |
Alternative sequenceiVSP_002937 | 737 – 750 | Missing in isoform KI25 and isoform TRKC. 1 PublicationAdd BLAST | 14 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L03813 mRNA Translation: AAA42285.1 L14445 mRNA Translation: AAA42282.1 L14446 mRNA Translation: AAA42283.1 L14447 mRNA Translation: AAA42284.1 S60953 mRNA Translation: AAB26714.2 S62924 mRNA Translation: AAB26716.2 S62933 mRNA Translation: AAB26715.2 |
RefSeqi | NP_001257584.1, NM_001270655.1 [Q03351-3] NP_001257585.1, NM_001270656.1 [Q03351-1] NP_062121.1, NM_019248.2 [Q03351-2] XP_017444550.1, XM_017589061.1 [Q03351-4] |
Genome annotation databases
Ensembli | ENSRNOT00000025536; ENSRNOP00000025536; ENSRNOG00000018674 [Q03351-5] ENSRNOT00000041839; ENSRNOP00000046059; ENSRNOG00000018674 [Q03351-2] ENSRNOT00000045165; ENSRNOP00000049463; ENSRNOG00000018674 [Q03351-3] ENSRNOT00000046849; ENSRNOP00000044402; ENSRNOG00000018674 [Q03351-1] |
GeneIDi | 29613 |
KEGGi | rno:29613 |
UCSCi | RGD:3214, rat [Q03351-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L03813 mRNA Translation: AAA42285.1 L14445 mRNA Translation: AAA42282.1 L14446 mRNA Translation: AAA42283.1 L14447 mRNA Translation: AAA42284.1 S60953 mRNA Translation: AAB26714.2 S62924 mRNA Translation: AAB26716.2 S62933 mRNA Translation: AAB26715.2 |
RefSeqi | NP_001257584.1, NM_001270655.1 [Q03351-3] NP_001257585.1, NM_001270656.1 [Q03351-1] NP_062121.1, NM_019248.2 [Q03351-2] XP_017444550.1, XM_017589061.1 [Q03351-4] |
3D structure databases
SMRi | Q03351 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 248241, 7 interactors |
DIPi | DIP-5718N |
IntActi | Q03351, 4 interactors |
MINTi | Q03351 |
STRINGi | 10116.ENSRNOP00000044402 |
PTM databases
GlyGeni | Q03351, 14 sites |
iPTMneti | Q03351 |
PhosphoSitePlusi | Q03351 |
Proteomic databases
PaxDbi | Q03351 |
Genome annotation databases
Ensembli | ENSRNOT00000025536; ENSRNOP00000025536; ENSRNOG00000018674 [Q03351-5] ENSRNOT00000041839; ENSRNOP00000046059; ENSRNOG00000018674 [Q03351-2] ENSRNOT00000045165; ENSRNOP00000049463; ENSRNOG00000018674 [Q03351-3] ENSRNOT00000046849; ENSRNOP00000044402; ENSRNOG00000018674 [Q03351-1] |
GeneIDi | 29613 |
KEGGi | rno:29613 |
UCSCi | RGD:3214, rat [Q03351-1] |
Organism-specific databases
CTDi | 4916 |
RGDi | 3214, Ntrk3 |
Phylogenomic databases
eggNOGi | KOG1026, Eukaryota |
GeneTreei | ENSGT00940000155645 |
HOGENOMi | CLU_000288_74_1_1 |
InParanoidi | Q03351 |
OMAi | RXVGGHT |
OrthoDBi | 295510at2759 |
PhylomeDBi | Q03351 |
TreeFami | TF106465 |
Enzyme and pathway databases
BRENDAi | 2.7.10.1, 5301 |
Reactomei | R-RNO-388844, Receptor-type tyrosine-protein phosphatases R-RNO-9034013, NTF3 activates NTRK3 signaling R-RNO-9034793, Activated NTRK3 signals through PLCG1 R-RNO-9603381, Activated NTRK3 signals through PI3K |
Miscellaneous databases
PROi | PR:Q03351 |
Gene expression databases
Bgeei | ENSRNOG00000018674, Expressed in frontal cortex and 21 other tissues |
ExpressionAtlasi | Q03351, baseline and differential |
Genevisiblei | Q03351, RN |
Family and domain databases
Gene3Di | 2.60.40.10, 2 hits 3.80.10.10, 1 hit |
InterProi | View protein in InterPro IPR000483, Cys-rich_flank_reg_C IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR013098, Ig_I-set IPR003599, Ig_sub IPR013151, Immunoglobulin IPR011009, Kinase-like_dom_sf IPR001611, Leu-rich_rpt IPR032675, LRR_dom_sf IPR000372, LRRNT IPR020777, NTRK IPR020446, NTRK3 IPR031635, NTRK_LRRCT IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR001245, Ser-Thr/Tyr_kinase_cat_dom IPR008266, Tyr_kinase_AS IPR020635, Tyr_kinase_cat_dom IPR002011, Tyr_kinase_rcpt_2_CS |
Pfami | View protein in Pfam PF07679, I-set, 1 hit PF00047, ig, 1 hit PF13855, LRR_8, 1 hit PF16920, LRRCT_2, 1 hit PF01462, LRRNT, 1 hit PF07714, PK_Tyr_Ser-Thr, 2 hits |
PRINTSi | PR01939, NTKRECEPTOR PR01942, NTKRECEPTOR3 PR00109, TYRKINASE |
SMARTi | View protein in SMART SM00409, IG, 1 hit SM00082, LRRCT, 1 hit SM00013, LRRNT, 1 hit SM00219, TyrKc, 1 hit |
SUPFAMi | SSF48726, SSF48726, 2 hits SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 1 hit PS51450, LRR, 1 hit PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00109, PROTEIN_KINASE_TYR, 1 hit PS00239, RECEPTOR_TYR_KIN_II, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | NTRK3_RAT | |
Accessioni | Q03351Primary (citable) accession number: Q03351 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1993 |
Last sequence update: | February 1, 1994 | |
Last modified: | February 23, 2022 | |
This is version 203 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families