Glycine-rich RNA-binding protein 7

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

Miscellaneous

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• double-stranded DNA binding Source: TAIR <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide%2Dgo%2Devidence%2Dcodes#ida">GO evidence code guide</a></p> Inferred from direct assayⁱ
  • Ref.13

    "Characterization of transgenic Arabidopsis plants overexpressing GR-RBP4 under high salinity, dehydration, or cold stress."
    Kwak K.J., Kim Y.O., Kang H.
    J. Exp. Bot. 56:3007-3016(2005) [PubMed] [Europe PMC] [Abstract]

    Cited for: INDUCTION BY COLD; DEHYDRATION AND SALT, FUNCTION.
• mRNA binding Source: TAIRInferred from direct assayⁱ
  • Ref.32

    "An hnRNP-like RNA-binding protein affects alternative splicing by in vivo interaction with transcripts in Arabidopsis thaliana."
    Streitner C., Koester T., Simpson C.G., Shaw P., Danisman S., Brown J.W., Staiger D.
    Nucleic Acids Res. 40:11240-11255(2012) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, MUTAGENESIS OF ARG-49.
  • "In Planta Determination of the mRNA-Binding Proteome of Arabidopsis Etiolated Seedlings."
    Reichel M., Liao Y., Rettel M., Ragan C., Evers M., Alleaume A.M., Horos R., Hentze M.W., Preiss T., Millar A.A.
    Plant Cell 28:2435-2452(2016) [PubMed] [Europe PMC] [Abstract]
  • "Discovering the RNA-Binding Proteome of Plant Leaves with an Improved RNA Interactome Capture Method."
    Bach-Pages M., Homma F., Kourelis J., Kaschani F., Mohammed S., Kaiser M., van der Hoorn R.A.L., Castello A., Preston G.M.
    Biomolecules 10:0-0(2020) [PubMed] [Europe PMC] [Abstract]
• RNA binding Source: UniProtKBInferred from direct assayⁱ
  • Ref.13

    "Characterization of transgenic Arabidopsis plants overexpressing GR-RBP4 under high salinity, dehydration, or cold stress."
    Kwak K.J., Kim Y.O., Kang H.
    J. Exp. Bot. 56:3007-3016(2005) [PubMed] [Europe PMC] [Abstract]

    Cited for: INDUCTION BY COLD; DEHYDRATION AND SALT, FUNCTION.
• single-stranded DNA binding Source: TAIRInferred from direct assayⁱ
  • Ref.13

    "Characterization of transgenic Arabidopsis plants overexpressing GR-RBP4 under high salinity, dehydration, or cold stress."
    Kwak K.J., Kim Y.O., Kang H.
    J. Exp. Bot. 56:3007-3016(2005) [PubMed] [Europe PMC] [Abstract]

    Cited for: INDUCTION BY COLD; DEHYDRATION AND SALT, FUNCTION.

GO - Biological processⁱ

• alternative mRNA splicing, via spliceosome Source: TAIR <p>Inferred from Mutant Phenotype</p> <p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors.</p> <p>More information in the <a href="http://geneontology.org/page/guide%2Dgo%2Devidence%2Dcodes#imp">GO evidence code guide</a></p> Inferred from mutant phenotypeⁱ
  • Ref.32

    "An hnRNP-like RNA-binding protein affects alternative splicing by in vivo interaction with transcripts in Arabidopsis thaliana."
    Streitner C., Koester T., Simpson C.G., Shaw P., Danisman S., Brown J.W., Staiger D.
    Nucleic Acids Res. 40:11240-11255(2012) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, MUTAGENESIS OF ARG-49.
• circadian rhythm Source: TAIR <p>Inferred from Expression Pattern</p> <p>Covers cases where the annotation is inferred from the timing or location of expression of a gene.</p> <p>More information in the <a href="http://geneontology.org/page/guide%2Dgo%2Devidence%2Dcodes#iep">GO evidence code guide</a></p> Inferred from expression patternⁱ
  • Ref.8

    "AtGRP7, a nuclear RNA-binding protein as a component of a circadian-regulated negative feedback loop in Arabidopsis thaliana."
    Heintzen C., Nater M., Apel K., Staiger D.
    Proc. Natl. Acad. Sci. U.S.A. 94:8515-8520(1997) [PubMed] [Europe PMC] [Abstract]

    Cited for: INDUCTION BY CIRCADIAN RHYTHM, FUNCTION.
• DNA duplex unwinding Source: TAIRInferred from direct assayⁱ
  • Ref.16

    "Cold shock domain proteins and glycine-rich RNA-binding proteins from Arabidopsis thaliana can promote the cold adaptation process in Escherichia coli."
    Kim J.S., Park S.J., Kwak K.J., Kim Y.O., Kim J.Y., Song J., Jang B., Jung C.-H., Kang H.
    Nucleic Acids Res. 35:506-516(2007) [PubMed] [Europe PMC] [Abstract]

    Cited for: INDUCTION BY COLD, FUNCTION.
• innate immune response Source: TAIRInferred from direct assayⁱ
  • Ref.15

    "A type III effector ADP-ribosylates RNA-binding proteins and quells plant immunity."
    Fu Z.Q., Guo M., Jeong B.R., Tian F., Elthon T.E., Cerny R.L., Staiger D., Alfano J.R.
    Nature 447:284-288(2007) [PubMed] [Europe PMC] [Abstract]

    Cited for: DISRUPTION PHENOTYPE, ADP-RIBOSYLATION, IDENTIFICATION BY MASS SPECTROMETRY, MUTAGENESIS OF ARG-47 AND ARG-49, SUBCELLULAR LOCATION.
• mRNA export from nucleus Source: TAIRInferred from mutant phenotypeⁱ
  • Ref.21

    "Glycine-rich RNA-binding protein 7 affects abiotic stress responses by regulating stomata opening and closing in Arabidopsis thaliana."
    Kim J.S., Jung H.J., Lee H.J., Kim K.A., Goh C.H., Woo Y., Oh S.H., Han Y.S., Kang H.
    Plant J. 55:455-466(2008) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, DISRUPTION PHENOTYPE, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
• regulation of stomatal movement Source: TAIRInferred from mutant phenotypeⁱ
  • Ref.21

    "Glycine-rich RNA-binding protein 7 affects abiotic stress responses by regulating stomata opening and closing in Arabidopsis thaliana."
    Kim J.S., Jung H.J., Lee H.J., Kim K.A., Goh C.H., Woo Y., Oh S.H., Han Y.S., Kang H.
    Plant J. 55:455-466(2008) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, DISRUPTION PHENOTYPE, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
• response to cadmium ion Source: TAIRInferred from expression patternⁱ
  • "The early responses of Arabidopsis thaliana cells to cadmium exposure explored by protein and metabolite profiling analyses."
    Sarry J.-E., Kuhn L., Ducruix C., Lafaye A., Junot C., Hugouvieux V., Jourdain A., Bastien O., Fievet J.B., Vailhen D., Amekraz B., Moulin C., Ezan E., Garin J., Bourguignon J.
    Proteomics 6:2180-2198(2006) [PubMed] [Europe PMC] [Abstract]
• response to cold Source: UniProtKBInferred from expression patternⁱ
  • Ref.13

    "Characterization of transgenic Arabidopsis plants overexpressing GR-RBP4 under high salinity, dehydration, or cold stress."
    Kwak K.J., Kim Y.O., Kang H.
    J. Exp. Bot. 56:3007-3016(2005) [PubMed] [Europe PMC] [Abstract]

    Cited for: INDUCTION BY COLD; DEHYDRATION AND SALT, FUNCTION.
• response to osmotic stress Source: TAIRInferred from mutant phenotypeⁱ
  • Ref.21

    "Glycine-rich RNA-binding protein 7 affects abiotic stress responses by regulating stomata opening and closing in Arabidopsis thaliana."
    Kim J.S., Jung H.J., Lee H.J., Kim K.A., Goh C.H., Woo Y., Oh S.H., Han Y.S., Kang H.
    Plant J. 55:455-466(2008) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, DISRUPTION PHENOTYPE, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
• response to salt stress Source: UniProtKBInferred from expression patternⁱ
  • Ref.13

    "Characterization of transgenic Arabidopsis plants overexpressing GR-RBP4 under high salinity, dehydration, or cold stress."
    Kwak K.J., Kim Y.O., Kang H.
    J. Exp. Bot. 56:3007-3016(2005) [PubMed] [Europe PMC] [Abstract]

    Cited for: INDUCTION BY COLD; DEHYDRATION AND SALT, FUNCTION.
• response to water deprivation Source: UniProtKBInferred from expression patternⁱ
  • Ref.13

    "Characterization of transgenic Arabidopsis plants overexpressing GR-RBP4 under high salinity, dehydration, or cold stress."
    Kwak K.J., Kim Y.O., Kang H.
    J. Exp. Bot. 56:3007-3016(2005) [PubMed] [Europe PMC] [Abstract]

    Cited for: INDUCTION BY COLD; DEHYDRATION AND SALT, FUNCTION.
• response to zinc ion Source: TAIRInferred from expression patternⁱ
  • "Identification of zinc-responsive proteins in the roots of Arabidopsis thaliana using a highly improved method of two-dimensional electrophoresis."
    Fukao Y., Ferjani A., Fujiwara M., Nishimori Y., Ohtsu I.
    Plant Cell Physiol. 50:2234-2239(2009) [PubMed] [Europe PMC] [Abstract]
• RNA secondary structure unwinding Source: TAIRInferred from direct assayⁱ
  • Ref.16

    "Cold shock domain proteins and glycine-rich RNA-binding proteins from Arabidopsis thaliana can promote the cold adaptation process in Escherichia coli."
    Kim J.S., Park S.J., Kwak K.J., Kim Y.O., Kim J.Y., Song J., Jang B., Jung C.-H., Kang H.
    Nucleic Acids Res. 35:506-516(2007) [PubMed] [Europe PMC] [Abstract]

    Cited for: INDUCTION BY COLD, FUNCTION.
• vegetative to reproductive phase transition of meristem Source: TAIRInferred from mutant phenotypeⁱ
  • Ref.22

    "The small glycine-rich RNA binding protein AtGRP7 promotes floral transition in Arabidopsis thaliana."
    Streitner C., Danisman S., Wehrle F., Schoening J.C., Alfano J.R., Staiger D.
    Plant J. 56:239-250(2008) [PubMed] [Europe PMC] [Abstract]

    Cited for: FUNCTION, DISRUPTION PHENOTYPE.

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

Keywords - Cellular componentⁱ

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechⁱ

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypeⁱ

Mutagenesis

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingⁱ

Molecule processing

Amino acid modifications

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationⁱ

Keywords - PTMⁱ

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressionⁱ

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityⁱ

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductionⁱ

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structureⁱ

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsⁱ

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structureⁱ

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Domains and Repeats

Region

Compositional bias

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domainⁱ

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)ⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingⁱ: The displayed sequence is further processed into a mature form.

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

        10         20         30         40         50
MASGDVEYRC FVGGLAWATD DRALETAFAQ YGDVIDSKII NDRETGRSRG 
        60         70         80         90        100
FGFVTFKDEK AMKDAIEGMN GQDLDGRSIT VNEAQSRGSG GGGGHRGGGG 
       110        120        130        140        150
GGYRSGGGGG YSGGGGSYGG GGGRREGGGG YSGGGGGYSS RGGGGGSYGG 
       160        170 
GRREGGGGYG GGEGGGYGGS GGGGGW                           

        10         20         30         40 
MASGDVEYRC FVGGLAWATD DRALETAFAQ YGDVIDSKVC YTPRSDSE   

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautionⁱ

Experimental Info

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityⁱ

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 100% Identity
• 90% Identity
• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

Keywords - Technical termⁱ

Documents

1. Arabidopsis thaliana
   Arabidopsis thaliana: entries and gene names
2. SIMILARITY comments
   Index of protein domains and families