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Protein

Major surface trophozoite antigen 11

Gene

TSP11

Organism
Giardia intestinalis (Giardia lamblia)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Major surface trophozoite antigen 11
Gene namesi
Name:TSP11
OrganismiGiardia intestinalis (Giardia lamblia)
Taxonomic identifieri5741 [NCBI]
Taxonomic lineageiEukaryotaDiplomonadidaHexamitidaeGiardiinaeGiardia

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini18 – 633ExtracellularSequence analysisAdd BLAST616
Transmembranei634 – 662HelicalSequence analysisAdd BLAST29
Topological domaini663 – 667CytoplasmicSequence analysis5

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Add BLAST17
ChainiPRO_000003646018 – 667Major surface trophozoite antigen 11Add BLAST650

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi591N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi630N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliQ03185
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domaini

Sequence similaritiesi

Keywords - Domaini

Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J36Z Eukaryota
ENOG4111ZF3 LUCA

Family and domain databases

InterProiView protein in InterPro
IPR000742 EGF-like_dom
IPR006212 Furin_repeat
IPR005127 Giardia_VSP
IPR009030 Growth_fac_rcpt_cys_sf
PfamiView protein in Pfam
PF03302 VSP, 1 hit
SMARTiView protein in SMART
SM00181 EGF, 5 hits
SM00261 FU, 6 hits
SUPFAMiSSF57184 SSF57184, 3 hits

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q03185-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLLAIFYFVI STLTAKCTTQ TQTCEAEKCE MVGETEICTR CQTGKVPIDG
60 70 80 90 100
KCVDATANAN CKNASGDGDA NQVCGKMSSV PGNTLCTTVS PDGVCSVAAN
110 120 130 140 150
EYFVPPNADA THDSVVSCSE ETPIHLANNK QYIGVAGCAT CSAPKAPGED
160 170 180 190 200
NTPKAATCTK CAAGFLHTPS EGLSSCEETC PEGYFGHTAT AESKKTCKSC
210 220 230 240 250
TGGSSEAPNV KGIGDCLKCM YNEASGNTLT CEKCSAQKKP SLDKTSCNDC
260 270 280 290 300
TGQNCAFCSS SGGDCEGCDS GFILDGQNCV KSDCKTENCK ACTNPKAANE
310 320 330 340 350
VCTECISTHH LTPTSQCVQY CQALGNYYAG TNADNKKACK ECTVANCKTC
360 370 380 390 400
NDQGQCQTCN DGFYKNGDAC SPCHESCKTC SAGTASDCTE CPTGKALKYG
410 420 430 440 450
NDGTKGTCGE GCTTGQGSGA CKTCGLTIDG ASYCSECDTQ NEYPQNGICT
460 470 480 490 500
STTARTVATC KNSNVANGIC SSCTNGFLRM NGGCYETTKF PGKSVCEGAN
510 520 530 540 550
ADADTCKAPV PGYKVEAGKL VMCSKGCDTC SDATTCTKCG DGYTKIENSQ
560 570 580 590 600
TCTKCDSSCE TCTGAATTCK VCATGYYKTA LGESTCTSCE NDSNGVIGVK
610 620 630 640 650
GCLNCAPPSS STGSVLCYLM KGENTGGSVN KSGLSTGAIA GISVAAVVVV
660
AGLVGFLCWW FICRGKA
Length:667
Mass (Da):68,476
Last modified:June 1, 1994 - v1
Checksum:i1DD9572703232B8D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M95814 Genomic DNA Translation: AAA02687.1
PIRiA48579

Similar proteinsi

Entry informationi

Entry nameiTS11_GIAIN
AccessioniPrimary (citable) accession number: Q03185
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: February 28, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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