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UniProtKB - Q03161 (YMY9_YEAST)
Protein
Glucose-6-phosphate 1-epimerase
Gene
YMR099C
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Catalyzes the interconversion between the alpha and beta anomers from at least three hexose 6-phosphate sugars (Glc6P, Gal6P, and Man6P).
1 PublicationMiscellaneous
Present with 8580 molecules/cell in log phase SD medium.1 Publication
Catalytic activityi
- EC:5.1.3.151 Publication
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 57 | Substrate1 Publication | 1 | |
Binding sitei | 81 | Substrate1 Publication | 1 | |
Binding sitei | 86 | Substrate1 Publication | 1 | |
Active sitei | 159 | 1 Publication | 1 | |
Binding sitei | 203 | Substrate1 Publication | 1 | |
Active sitei | 264 | 1 Publication | 1 |
GO - Molecular functioni
- carbohydrate binding Source: InterPro
- glucose-6-phosphate 1-epimerase activity Source: SGD
GO - Biological processi
- cellular carbohydrate metabolic process Source: SGD
Keywordsi
Molecular function | Isomerase |
Enzyme and pathway databases
BRENDAi | 5.3.3.3, 1455 |
Names & Taxonomyi
Protein namesi | Recommended name: Glucose-6-phosphate 1-epimeraseCurated (EC:5.1.3.151 Publication)Alternative name(s): D-hexose-6-phosphate mutarotase1 Publication |
Gene namesi | Ordered Locus Names:YMR099C ORF Names:YM6543.06C |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
SGDi | S000004705, YMR099C |
VEuPathDBi | FungiDB:YMR099C |
Subcellular locationi
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000213035 | 1 – 297 | Glucose-6-phosphate 1-epimeraseAdd BLAST | 297 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 88 | PhosphoserineCombined sources | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
MaxQBi | Q03161 |
PaxDbi | Q03161 |
PRIDEi | Q03161 |
PTM databases
iPTMneti | Q03161 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 35275, 87 interactors |
IntActi | Q03161, 12 interactors |
MINTi | Q03161 |
STRINGi | 4932.YMR099C |
Miscellaneous databases
RNActi | Q03161, protein |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | Q03161 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q03161 |
Family & Domainsi
Sequence similaritiesi
Belongs to the glucose-6-phosphate 1-epimerase family.Curated
Phylogenomic databases
eggNOGi | KOG1594, Eukaryota |
GeneTreei | ENSGT00390000015166 |
HOGENOMi | CLU_048345_2_0_1 |
InParanoidi | Q03161 |
OMAi | TQALHSY |
Family and domain databases
CDDi | cd09020, D-hex-6-P-epi_like, 1 hit |
Gene3Di | 2.70.98.10, 1 hit |
InterProi | View protein in InterPro IPR008183, Aldose_1/G6P_1-epimerase IPR025532, G6P_1-epimerase IPR011013, Gal_mutarotase_sf_dom IPR014718, GH-type_carb-bd |
Pfami | View protein in Pfam PF01263, Aldose_epim, 1 hit |
PIRSFi | PIRSF016020, PHexose_mutarotase, 1 hit |
SUPFAMi | SSF74650, SSF74650, 1 hit |
i Sequence
Sequence statusi: Complete.
Q03161-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPIKETDKEV VLTHPADETT SVHILKYGAT VYSWKLKSEE QLWLSTAAKL
60 70 80 90 100
DGSKPVRGGI PLVFPVFGKN STDEHLSKLP QHGLARNSTW EFLGQTKENP
110 120 130 140 150
PTVQFGLKPE IANPELTKLW PMDYLLILTV ELGSDYLKTA IEVENTSSSK
160 170 180 190 200
ELKFNWLFHT YFRIEDIEGT MVSNLAGMKL YDQLLKESYV DKHPVVTFNQ
210 220 230 240 250
ETDVIYQNVS AERAIQIVDK GVQIHTLKRY NLPDTVVWNP WIEKSQGMAD
260 270 280 290
FEPKTGYQQM ICIEPGHVHD FISLAPGKKW NAYQLLCKEE LKYQAIQ
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z49807 Genomic DNA Translation: CAA89900.1 BK006946 Genomic DNA Translation: DAA09996.1 |
PIRi | S55085 |
RefSeqi | NP_013817.1, NM_001182599.1 |
Genome annotation databases
EnsemblFungii | YMR099C_mRNA; YMR099C; YMR099C |
GeneIDi | 855125 |
KEGGi | sce:YMR099C |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z49807 Genomic DNA Translation: CAA89900.1 BK006946 Genomic DNA Translation: DAA09996.1 |
PIRi | S55085 |
RefSeqi | NP_013817.1, NM_001182599.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
2CIQ | X-ray | 1.70 | A | 1-297 | [»] | |
2CIR | X-ray | 1.60 | A | 1-297 | [»] | |
2CIS | X-ray | 1.62 | A | 1-297 | [»] | |
SMRi | Q03161 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 35275, 87 interactors |
IntActi | Q03161, 12 interactors |
MINTi | Q03161 |
STRINGi | 4932.YMR099C |
PTM databases
iPTMneti | Q03161 |
Proteomic databases
MaxQBi | Q03161 |
PaxDbi | Q03161 |
PRIDEi | Q03161 |
Genome annotation databases
EnsemblFungii | YMR099C_mRNA; YMR099C; YMR099C |
GeneIDi | 855125 |
KEGGi | sce:YMR099C |
Organism-specific databases
SGDi | S000004705, YMR099C |
VEuPathDBi | FungiDB:YMR099C |
Phylogenomic databases
eggNOGi | KOG1594, Eukaryota |
GeneTreei | ENSGT00390000015166 |
HOGENOMi | CLU_048345_2_0_1 |
InParanoidi | Q03161 |
OMAi | TQALHSY |
Enzyme and pathway databases
BRENDAi | 5.3.3.3, 1455 |
Miscellaneous databases
EvolutionaryTracei | Q03161 |
PROi | PR:Q03161 |
RNActi | Q03161, protein |
Family and domain databases
CDDi | cd09020, D-hex-6-P-epi_like, 1 hit |
Gene3Di | 2.70.98.10, 1 hit |
InterProi | View protein in InterPro IPR008183, Aldose_1/G6P_1-epimerase IPR025532, G6P_1-epimerase IPR011013, Gal_mutarotase_sf_dom IPR014718, GH-type_carb-bd |
Pfami | View protein in Pfam PF01263, Aldose_epim, 1 hit |
PIRSFi | PIRSF016020, PHexose_mutarotase, 1 hit |
SUPFAMi | SSF74650, SSF74650, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | YMY9_YEAST | |
Accessioni | Q03161Primary (citable) accession number: Q03161 Secondary accession number(s): D6VZS2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | November 1, 1997 | |
Last modified: | February 23, 2022 | |
This is version 150 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - Yeast chromosome XIII
Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names - Uncharacterized protein families (UPF)
List of uncharacterized protein family (UPF) entries - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families