UniProtKB - Q02UV9 (DCTA1_PSEAB)
Protein
C4-dicarboxylate transport protein 1
Gene
dctA1
Organism
Pseudomonas aeruginosa (strain UCBPP-PA14)
Status
Functioni
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.UniRule annotation
GO - Molecular functioni
- symporter activity Source: UniProtKB-UniRule
GO - Biological processi
- dicarboxylic acid transport Source: UniProtKB-UniRule
Keywordsi
Biological process | Symport, Transport |
Enzyme and pathway databases
BioCyci | PAER208963:G1G74-124-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: C4-dicarboxylate transport protein 1UniRule annotation |
Gene namesi | Name:dctA1UniRule annotation Ordered Locus Names:PA14_01460 |
Organismi | Pseudomonas aeruginosa (strain UCBPP-PA14) |
Taxonomic identifieri | 208963 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › |
Proteomesi |
|
Subcellular locationi
- Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 14 – 34 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 47 – 67 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 83 – 103 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 157 – 177 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 195 – 215 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 226 – 246 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 312 – 332 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 359 – 379 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 385 – 405 | HelicalUniRule annotationAdd BLAST | 21 |
GO - Cellular componenti
- integral component of membrane Source: UniProtKB-KW
- plasma membrane Source: UniProtKB-SubCell
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000321992 | 1 – 449 | C4-dicarboxylate transport protein 1Add BLAST | 449 |
Family & Domainsi
Sequence similaritiesi
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. [View classification]UniRule annotation
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
HOGENOMi | CLU_019375_7_0_6 |
OMAi | VDWFMGI |
Family and domain databases
Gene3Di | 1.10.3860.10, 1 hit |
HAMAPi | MF_01300, C4_dicarb_transport, 1 hit |
InterProi | View protein in InterPro IPR023954, C4_dicarb_transport IPR001991, Na-dicarboxylate_symporter IPR018107, Na-dicarboxylate_symporter_CS IPR036458, Na:dicarbo_symporter_sf |
PANTHERi | PTHR42865, PTHR42865, 1 hit |
Pfami | View protein in Pfam PF00375, SDF, 1 hit |
SUPFAMi | SSF118215, SSF118215, 1 hit |
PROSITEi | View protein in PROSITE PS00714, NA_DICARBOXYL_SYMP_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q02UV9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
METPAMFIKR CSRSIFLQVV IGLVIGVICG VGIPDLAVQM KPLGDGFIKL
60 70 80 90 100
IKMLIALIVF CVVVNGISGA GDLKKVGRIG LKSVIYFEIL TTIALVLGLV
110 120 130 140 150
VAYSLGLGSG ANIHLNELPA GDVALYTGRT QEIHGPVAFL MGLIPTSVFS
160 170 180 190 200
AFAENDILQV LLFSVLFGSA LNLVGEQASG VARLINEFSH IVFRIMGMIV
210 220 230 240 250
RLAPLGVFGA VAFTTARYGV DSLSHLGALV LVFYATCLVF VMAVLGSVLR
260 270 280 290 300
LSGVRMLPFL RYFREELMIV MGTASSDAVL PQVMRKLEHM GIRSSTVGLV
310 320 330 340 350
IPTGYSFNLD GFSIYLTLAV VFIAHVTGTP LAMTDLVTIL LVSLVTSKGA
360 370 380 390 400
HGIPGSALVI LAATLTAVPA IPVAGLVLVL SVDWFMGIGR ALTNLIGNCV
410 420 430 440
ATVTIARWEN DIDMPRAQAI LDGRLEAPAK ADGEPLKRSA VAGEGKLHG
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000438 Genomic DNA Translation: ABJ15076.1 |
RefSeqi | WP_003137006.1, NZ_CP034244.1 |
Genome annotation databases
EnsemblBacteriai | ABJ15076; ABJ15076; PA14_01460 |
KEGGi | pau:PA14_01460 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000438 Genomic DNA Translation: ABJ15076.1 |
RefSeqi | WP_003137006.1, NZ_CP034244.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
EnsemblBacteriai | ABJ15076; ABJ15076; PA14_01460 |
KEGGi | pau:PA14_01460 |
Phylogenomic databases
HOGENOMi | CLU_019375_7_0_6 |
OMAi | VDWFMGI |
Enzyme and pathway databases
BioCyci | PAER208963:G1G74-124-MONOMER |
Family and domain databases
Gene3Di | 1.10.3860.10, 1 hit |
HAMAPi | MF_01300, C4_dicarb_transport, 1 hit |
InterProi | View protein in InterPro IPR023954, C4_dicarb_transport IPR001991, Na-dicarboxylate_symporter IPR018107, Na-dicarboxylate_symporter_CS IPR036458, Na:dicarbo_symporter_sf |
PANTHERi | PTHR42865, PTHR42865, 1 hit |
Pfami | View protein in Pfam PF00375, SDF, 1 hit |
SUPFAMi | SSF118215, SSF118215, 1 hit |
PROSITEi | View protein in PROSITE PS00714, NA_DICARBOXYL_SYMP_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | DCTA1_PSEAB | |
Accessioni | Q02UV9Primary (citable) accession number: Q02UV9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 26, 2008 |
Last sequence update: | November 14, 2006 | |
Last modified: | December 2, 2020 | |
This is version 80 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |