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Protein

Protein MGR2

Gene

MGR2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Required for cell viability in cells lacking mitochondrial DNA.1 Publication

GO - Biological processi

  • protein import into mitochondrial inner membrane Source: SGD
  • protein import into mitochondrial matrix Source: SGD

Enzyme and pathway databases

BioCyciYEAST:G3O-34001-MONOMER

Protein family/group databases

TCDBi1.A.111.1.3 the reactive oxygen species modulator 1 (romo1) family

Names & Taxonomyi

Protein namesi
Recommended name:
Protein MGR2
Alternative name(s):
Mitochondrial genome-required protein 2
Gene namesi
Name:MGR2
Ordered Locus Names:YPL098C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XVI

Organism-specific databases

EuPathDBiFungiDB:YPL098C
SGDiS000006019 MGR2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 22CytoplasmicSequence analysisAdd BLAST22
Transmembranei23 – 43HelicalSequence analysisAdd BLAST21
Topological domaini44 – 56ExtracellularSequence analysisAdd BLAST13
Transmembranei57 – 77HelicalSequence analysisAdd BLAST21
Topological domaini78 – 113CytoplasmicSequence analysisAdd BLAST36

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002522781 – 113Protein MGR2Add BLAST113

Proteomic databases

MaxQBiQ02889
PaxDbiQ02889
PRIDEiQ02889

Interactioni

Protein-protein interaction databases

BioGridi36082, 261 interactors
DIPiDIP-4556N
IntActiQ02889, 1 interactor
STRINGi4932.YPL098C

Structurei

3D structure databases

ProteinModelPortaliQ02889
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MGR2 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00390000005315
HOGENOMiHOG000184556
InParanoidiQ02889
OMAiLKMGAMM
OrthoDBiEOG092C5QP7

Family and domain databases

InterProiView protein in InterPro
IPR018450 Romo1/Mgr2
PANTHERiPTHR28525 PTHR28525, 1 hit
PfamiView protein in Pfam
PF10247 Romo1, 1 hit
SMARTiView protein in SMART
SM01378 Romo1, 1 hit

Sequencei

Sequence statusi: Complete.

Q02889-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPPLPQNYAQ QQPSNWDKFK MGLMMGTTVG VCTGILFGGF AIATQGPGPD
60 70 80 90 100
GVVRTLGKYI AGSAGTFGLF MSIGSIIRSD SESSPMSHPN LNLQQQARLE
110
MWKLRAKYGI RKD
Length:113
Mass (Da):12,252
Last modified:November 1, 1996 - v1
Checksum:i43BA58C679D86E93
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U43281 Genomic DNA Translation: AAB68201.1
AY558335 Genomic DNA Translation: AAS56661.1
BK006949 Genomic DNA Translation: DAA11334.1
PIRiS61968
RefSeqiNP_015227.1, NM_001183912.1

Genome annotation databases

EnsemblFungiiYPL098C; YPL098C; YPL098C
GeneIDi856006
KEGGisce:YPL098C

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U43281 Genomic DNA Translation: AAB68201.1
AY558335 Genomic DNA Translation: AAS56661.1
BK006949 Genomic DNA Translation: DAA11334.1
PIRiS61968
RefSeqiNP_015227.1, NM_001183912.1

3D structure databases

ProteinModelPortaliQ02889
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi36082, 261 interactors
DIPiDIP-4556N
IntActiQ02889, 1 interactor
STRINGi4932.YPL098C

Protein family/group databases

TCDBi1.A.111.1.3 the reactive oxygen species modulator 1 (romo1) family

Proteomic databases

MaxQBiQ02889
PaxDbiQ02889
PRIDEiQ02889

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYPL098C; YPL098C; YPL098C
GeneIDi856006
KEGGisce:YPL098C

Organism-specific databases

EuPathDBiFungiDB:YPL098C
SGDiS000006019 MGR2

Phylogenomic databases

GeneTreeiENSGT00390000005315
HOGENOMiHOG000184556
InParanoidiQ02889
OMAiLKMGAMM
OrthoDBiEOG092C5QP7

Enzyme and pathway databases

BioCyciYEAST:G3O-34001-MONOMER

Miscellaneous databases

PROiPR:Q02889

Family and domain databases

InterProiView protein in InterPro
IPR018450 Romo1/Mgr2
PANTHERiPTHR28525 PTHR28525, 1 hit
PfamiView protein in Pfam
PF10247 Romo1, 1 hit
SMARTiView protein in SMART
SM01378 Romo1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiMGR2_YEAST
AccessioniPrimary (citable) accession number: Q02889
Secondary accession number(s): D6W3R8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: November 1, 1996
Last modified: September 12, 2018
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast chromosome XVI
    Yeast (Saccharomyces cerevisiae) chromosome XVI: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
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