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Entry version 151 (11 Dec 2019)
Sequence version 1 (01 Nov 1996)
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Protein

Ras association domain-containing protein 7

Gene

RASSF7

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization.2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processApoptosis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ras association domain-containing protein 7
Alternative name(s):
HRAS1-related cluster protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RASSF7
Synonyms:C11orf13, HRC1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000099849.14

Human Gene Nomenclature Database

More...
HGNCi
HGNC:1166 RASSF7

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
143023 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q02833

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
8045

Open Targets

More...
OpenTargetsi
ENSG00000099849

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA25480

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q02833 Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
RASSF7

Domain mapping of disease mutations (DMDM)

More...
DMDMi
18202480

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000971731 – 373Ras association domain-containing protein 7Add BLAST373

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Polyubiquitinated and degraded by the proteasome upon prolonged stress stimuli.

Keywords - PTMi

Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q02833

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q02833

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q02833

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q02833

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q02833

PeptideAtlas

More...
PeptideAtlasi
Q02833

PRoteomics IDEntifications database

More...
PRIDEi
Q02833

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
33997
58129 [Q02833-1]
58130 [Q02833-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q02833

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q02833

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000099849 Expressed in 187 organ(s), highest expression level in right uterine tube

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q02833 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q02833 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA078015

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with MAP2K7 and GTP-bound NRAS.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
O436393EBI-929013,EBI-713635

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
113735, 34 interactors

Protein interaction database and analysis system

More...
IntActi
Q02833, 33 interactors

Molecular INTeraction database

More...
MINTi
Q02833

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000380713

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q02833 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q02833

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini6 – 89Ras-associatingPROSITE-ProRule annotationAdd BLAST84

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili175 – 227Sequence analysisAdd BLAST53
Coiled coili248 – 297Sequence analysisAdd BLAST50

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi130 – 149Pro-richAdd BLAST20
Compositional biasi228 – 236Pro-rich9
Compositional biasi304 – 322Pro-richAdd BLAST19

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1574 Eukaryota
ENOG410XPWB LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182839

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000013031

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q02833

KEGG Orthology (KO)

More...
KOi
K09855

Identification of Orthologs from Complete Genome Data

More...
OMAi
QHGNEVQ

Database of Orthologous Groups

More...
OrthoDBi
1442074at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q02833

TreeFam database of animal gene trees

More...
TreeFami
TF318385

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR033593 N-RASSF
IPR000159 RA_dom
IPR033631 RASSF7
IPR029071 Ubiquitin-like_domsf

The PANTHER Classification System

More...
PANTHERi
PTHR15286 PTHR15286, 2 hits
PTHR15286:SF11 PTHR15286:SF11, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00788 RA, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00314 RA, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54236 SSF54236, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50200 RA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q02833-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MLLGLAAMEL KVWVDGIQRV VCGVSEQTTC QEVVIALAQA IGQTGRFVLV
60 70 80 90 100
QRLREKERQL LPQECPVGAQ ATCGQFASDV QFVLRRTGPS LAGRPSSDSC
110 120 130 140 150
PPPERCLIRA SLPVKPRAAL GCEPRKTLTP EPAPSLSRPG PAAPVTPTPG
160 170 180 190 200
CCTDLRGLEL RVQRNAEELG HEAFWEQELR REQAREREGQ ARLQALSAAT
210 220 230 240 250
AEHAARLQAL DAQARALEAE LQLAAEAPGP PSPMASATER LHQDLAVQER
260 270 280 290 300
QSAEVQGSLA LVSRALEAAE RALQAQAQEL EELNRELRQC NLQQFIQQTG
310 320 330 340 350
AALPPPPRPD RGPPGTQGPL PPAREESLLG APSESHAGAQ PRPRGGPHDA
360 370
ELLEVAAAPA PEWCPLAAQP QAL
Length:373
Mass (Da):39,945
Last modified:November 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i55DF1DDB1C37CAF3
GO
Isoform 2 (identifier: Q02833-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     318-337: GPLPPAREESLLGAPSESHA → VGVVLGGGWEVRTWPSPTPS
     338-373: Missing.

Show »
Length:337
Mass (Da):36,343
Checksum:i0235F06486060BCE
GO
Isoform 3 (identifier: Q02833-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     318-373: GPLPPAREESLLGAPSESHAGAQPRPRGGPHDAELLEVAAAPAPEWCPLAAQPQAL → WPP

Show »
Length:320
Mass (Da):34,660
Checksum:i79AD59B6C06E3022
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0G2JMW4A0A0G2JMW4_HUMAN
Ras association domain-containing p...
RASSF7
373Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JLR5A0A0G2JLR5_HUMAN
Ras association domain-containing p...
RASSF7
337Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YEI0H0YEI0_HUMAN
Ras association domain-containing p...
RASSF7
194Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PM39E9PM39_HUMAN
Ras association domain-containing p...
RASSF7
83Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8W7Q0F8W7Q0_HUMAN
Ras association domain-containing p...
RASSF7
120Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0J9YYE4A0A0J9YYE4_HUMAN
Ras association domain-containing p...
RASSF7
120Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_02185989P → A1 PublicationCorresponds to variant dbSNP:rs2242183Ensembl.1
Natural variantiVAR_021860156R → Q. Corresponds to variant dbSNP:rs2242182Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_045623318 – 373GPLPP…QPQAL → WPP in isoform 3. 1 PublicationAdd BLAST56
Alternative sequenceiVSP_004136318 – 337GPLPP…SESHA → VGVVLGGGWEVRTWPSPTPS in isoform 2. 1 PublicationAdd BLAST20
Alternative sequenceiVSP_004137338 – 373Missing in isoform 2. 1 PublicationAdd BLAST36

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
M91083 mRNA Translation: AAA58667.1
AP006284 Genomic DNA No translation available.
CH471158 Genomic DNA Translation: EAX02351.1
BC106921 mRNA Translation: AAI06922.1
BC106922 mRNA Translation: AAI06923.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS44505.1 [Q02833-3]
CCDS44506.1 [Q02833-2]
CCDS7702.1 [Q02833-1]

Protein sequence database of the Protein Information Resource

More...
PIRi
A44478
B44478

NCBI Reference Sequences

More...
RefSeqi
NP_001137465.1, NM_001143993.1 [Q02833-2]
NP_001137466.1, NM_001143994.1 [Q02833-3]
NP_003466.1, NM_003475.3 [Q02833-1]
XP_016873850.1, XM_017018361.1
XP_016873851.1, XM_017018362.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000397582; ENSP00000380712; ENSG00000099849 [Q02833-2]
ENST00000397583; ENSP00000380713; ENSG00000099849 [Q02833-1]
ENST00000431809; ENSP00000403068; ENSG00000099849 [Q02833-2]
ENST00000454668; ENSP00000405606; ENSG00000099849 [Q02833-3]
ENST00000622905; ENSP00000479652; ENSG00000273859

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
8045

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:8045

UCSC genome browser

More...
UCSCi
uc001lqb.4 human [Q02833-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M91083 mRNA Translation: AAA58667.1
AP006284 Genomic DNA No translation available.
CH471158 Genomic DNA Translation: EAX02351.1
BC106921 mRNA Translation: AAI06922.1
BC106922 mRNA Translation: AAI06923.1
CCDSiCCDS44505.1 [Q02833-3]
CCDS44506.1 [Q02833-2]
CCDS7702.1 [Q02833-1]
PIRiA44478
B44478
RefSeqiNP_001137465.1, NM_001143993.1 [Q02833-2]
NP_001137466.1, NM_001143994.1 [Q02833-3]
NP_003466.1, NM_003475.3 [Q02833-1]
XP_016873850.1, XM_017018361.1
XP_016873851.1, XM_017018362.1

3D structure databases

SMRiQ02833
ModBaseiSearch...

Protein-protein interaction databases

BioGridi113735, 34 interactors
IntActiQ02833, 33 interactors
MINTiQ02833
STRINGi9606.ENSP00000380713

PTM databases

iPTMnetiQ02833
PhosphoSitePlusiQ02833

Polymorphism and mutation databases

BioMutaiRASSF7
DMDMi18202480

Proteomic databases

EPDiQ02833
jPOSTiQ02833
MassIVEiQ02833
MaxQBiQ02833
PaxDbiQ02833
PeptideAtlasiQ02833
PRIDEiQ02833
ProteomicsDBi33997
58129 [Q02833-1]
58130 [Q02833-2]

Protocols and materials databases

The DNASU plasmid repository

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DNASUi
8045

Genome annotation databases

EnsembliENST00000397582; ENSP00000380712; ENSG00000099849 [Q02833-2]
ENST00000397583; ENSP00000380713; ENSG00000099849 [Q02833-1]
ENST00000431809; ENSP00000403068; ENSG00000099849 [Q02833-2]
ENST00000454668; ENSP00000405606; ENSG00000099849 [Q02833-3]
ENST00000622905; ENSP00000479652; ENSG00000273859
GeneIDi8045
KEGGihsa:8045
UCSCiuc001lqb.4 human [Q02833-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
8045
DisGeNETi8045
EuPathDBiHostDB:ENSG00000099849.14

GeneCards: human genes, protein and diseases

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GeneCardsi
RASSF7
HGNCiHGNC:1166 RASSF7
HPAiHPA078015
MIMi143023 gene
neXtProtiNX_Q02833
OpenTargetsiENSG00000099849
PharmGKBiPA25480

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG1574 Eukaryota
ENOG410XPWB LUCA
GeneTreeiENSGT00950000182839
HOGENOMiHOG000013031
InParanoidiQ02833
KOiK09855
OMAiQHGNEVQ
OrthoDBi1442074at2759
PhylomeDBiQ02833
TreeFamiTF318385

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
RASSF7 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
8045
PharosiQ02833 Tbio

Protein Ontology

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PROi
PR:Q02833
RNActiQ02833 protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000099849 Expressed in 187 organ(s), highest expression level in right uterine tube
ExpressionAtlasiQ02833 baseline and differential
GenevisibleiQ02833 HS

Family and domain databases

InterProiView protein in InterPro
IPR033593 N-RASSF
IPR000159 RA_dom
IPR033631 RASSF7
IPR029071 Ubiquitin-like_domsf
PANTHERiPTHR15286 PTHR15286, 2 hits
PTHR15286:SF11 PTHR15286:SF11, 2 hits
PfamiView protein in Pfam
PF00788 RA, 1 hit
SMARTiView protein in SMART
SM00314 RA, 1 hit
SUPFAMiSSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS50200 RA, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRASF7_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q02833
Secondary accession number(s): G5E9N9, Q3KP41, Q3KP42
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: November 1, 1996
Last modified: December 11, 2019
This is version 151 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
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