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Protein

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1

Gene

NDUFB1

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processElectron transport, Respiratory chain, Transport

Protein family/group databases

TCDBi3.D.1.6.1 the h(+) or na(+)-translocating nadh dehydrogenase (ndh) family

Names & Taxonomyi

Protein namesi
Recommended name:
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1
Alternative name(s):
Complex I-MNLL
Short name:
CI-MNLL
NADH-ubiquinone oxidoreductase MNLL subunit
Gene namesi
Name:NDUFB1
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei10 – 26HelicalSequence analysisAdd BLAST17

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001188261 – 57NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1Add BLAST57

Proteomic databases

PaxDbiQ02378
PRIDEiQ02378

Interactioni

Subunit structurei

Complex I is composed of 45 different subunits.3 Publications

Protein-protein interaction databases

CORUMiQ02378
DIPiDIP-38823N
IntActiQ02378, 2 interactors
STRINGi9913.ENSBTAP00000020160

Structurei

3D structure databases

SMRiQ02378
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I NDUFB1 subunit family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J2ZX Eukaryota
ENOG410XXU1 LUCA
HOVERGENiHBG006501
InParanoidiQ02378
KOiK03957
OMAiQDQKLTA

Family and domain databases

InterProiView protein in InterPro
IPR012575 NADH_UbQ_OxRdtase_MNLL_su
PANTHERiPTHR15222 PTHR15222, 1 hit
PfamiView protein in Pfam
PF08040 NADH_oxidored, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD052001 NADH_UbQ_OxRdtase_MNLL_su, 1 hit

Sequencei

Sequence statusi: Complete.

Q02378-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLLQVVRDH WVHVLVPMGF VFGYYLDRKN DEKLTAFRNK SLLYKRELKP

NEEVTWK
Length:57
Mass (Da):6,966
Last modified:July 1, 1993 - v1
Checksum:i56D0A3C8CB046973
GO

Sequence cautioni

The sequence CAA44908 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X63223 mRNA Translation: CAA44908.1 Different initiation.
PIRiS28251
RefSeqiNP_787003.1, NM_175809.2
UniGeneiBt.62532

Genome annotation databases

GeneIDi327690
KEGGibta:327690

Similar proteinsi

Entry informationi

Entry nameiNDUB1_BOVIN
AccessioniPrimary (citable) accession number: Q02378
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: July 1, 1993
Last modified: February 28, 2018
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

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