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Protein

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7

Gene

NDUFB7

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processElectron transport, Respiratory chain, Transport

Enzyme and pathway databases

ReactomeiR-BTA-611105 Respiratory electron transport
R-BTA-6799198 Complex I biogenesis

Protein family/group databases

TCDBi3.D.1.6.1 the h(+) or na(+)-translocating nadh dehydrogenase (ndh) family

Names & Taxonomyi

Protein namesi
Recommended name:
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7
Alternative name(s):
Complex I-B18
Short name:
CI-B18
NADH-ubiquinone oxidoreductase B18 subunit
Gene namesi
Name:NDUFB7
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 7

Organism-specific databases

VGNCiVGNC:31966 NDUFB7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved
ChainiPRO_00001188102 – 137NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7Add BLAST136

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi2N-myristoyl glycine1 Publication1
Disulfide bondi59 ↔ 90PROSITE-ProRule annotation
Disulfide bondi69 ↔ 80PROSITE-ProRule annotation
Modified residuei73PhosphoserineBy similarity1

Keywords - PTMi

Disulfide bond, Lipoprotein, Myristate, Phosphoprotein

Proteomic databases

PaxDbiQ02368
PRIDEiQ02368

PTM databases

iPTMnetiQ02368

Expressioni

Gene expression databases

BgeeiENSBTAG00000012634

Interactioni

Subunit structurei

Complex I is composed of 45 different subunits.3 Publications

Protein-protein interaction databases

CORUMiQ02368
DIPiDIP-38797N
IntActiQ02368, 1 interactor
STRINGi9913.ENSBTAP00000016768

Structurei

3D structure databases

SMRiQ02368
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini56 – 98CHCHPROSITE-ProRule annotationAdd BLAST43

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi59 – 69Cx9C motif 1PROSITE-ProRule annotationAdd BLAST11
Motifi80 – 90Cx9C motif 2PROSITE-ProRule annotationAdd BLAST11

Domaini

Contains two C-X9-C motifs that are predicted to form a helix-coil-helix structure, permitting the formation of intramolecular disulfide bonds.By similarity

Sequence similaritiesi

Belongs to the complex I NDUFB7 subunit family.Curated

Phylogenomic databases

eggNOGiKOG3468 Eukaryota
ENOG411230N LUCA
GeneTreeiENSGT00390000018759
HOGENOMiHOG000199343
HOVERGENiHBG001948
InParanoidiQ02368
KOiK03963
OMAiVMRMKEY
OrthoDBiEOG091G10SJ
TreeFamiTF315152

Family and domain databases

InterProiView protein in InterPro
IPR008698 NADH_UbQ_OxRdtase_B18_su
PANTHERiPTHR20900 PTHR20900, 1 hit
PfamiView protein in Pfam
PF05676 NDUF_B7, 1 hit
PROSITEiView protein in PROSITE
PS51808 CHCH, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q02368-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGAHLARRYL GDASVEPDPL RMPTFPPDYG FPERKEREMV ATQQEMNDAQ
60 70 80 90 100
LVLQQRDYCA HYLIRFLKCK RDSFPNFLAC KHERHDWDYC EHLDYVKRMK
110 120 130
EFERERRLLQ RKKRREQREA DMAKGLGPGE VAPEVAL
Length:137
Mass (Da):16,398
Last modified:January 23, 2007 - v2
Checksum:iF75B1365E32DC573
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X63210 mRNA Translation: CAA44895.1
BC102482 mRNA Translation: AAI02483.1
PIRiS28247
RefSeqiNP_788833.1, NM_176660.2
UniGeneiBt.64

Genome annotation databases

EnsembliENSBTAT00000016768; ENSBTAP00000016768; ENSBTAG00000012634
GeneIDi338065
KEGGibta:338065

Similar proteinsi

Entry informationi

Entry nameiNDUB7_BOVIN
AccessioniPrimary (citable) accession number: Q02368
Secondary accession number(s): Q3T0A1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: January 23, 2007
Last modified: June 20, 2018
This is version 118 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

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