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Protein

M-protein, striated muscle

Gene
N/A
Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Is a structural constituent of myofibrillar M-band in striated muscle.

GO - Molecular functioni

  • actin filament binding Source: GO_Central
  • muscle alpha-actinin binding Source: GO_Central
  • structural constituent of muscle Source: GO_Central

GO - Biological processi

Keywordsi

Molecular functionMuscle protein

Names & Taxonomyi

Protein namesi
Recommended name:
M-protein, striated muscle
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000726831 – 1450M-protein, striated muscleAdd BLAST1450

Proteomic databases

PaxDbiQ02173
PRIDEiQ02173

Expressioni

Tissue specificityi

Expressed in pectoralis and cardiac muscle.

Developmental stagei

Can be detected by day 10-13 in ovo, the content is gradually increased throughout the ovo development and reached its peak after hatching.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000026310

Structurei

3D structure databases

ProteinModelPortaliQ02173
SMRiQ02173
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini142 – 233Ig-like C2-type 1Add BLAST92
Domaini254 – 359Ig-like C2-type 2Add BLAST106
Domaini373 – 468Fibronectin type-III 1PROSITE-ProRule annotationAdd BLAST96
Domaini501 – 596Fibronectin type-III 2PROSITE-ProRule annotationAdd BLAST96
Domaini602 – 695Fibronectin type-III 3PROSITE-ProRule annotationAdd BLAST94
Domaini698 – 800Fibronectin type-III 4PROSITE-ProRule annotationAdd BLAST103
Domaini803 – 900Fibronectin type-III 5PROSITE-ProRule annotationAdd BLAST98
Domaini899 – 995Ig-like C2-type 3Add BLAST97
Domaini1002 – 1115Ig-like C2-type 4Add BLAST114
Domaini1118 – 1204Ig-like C2-type 5Add BLAST87
Domaini1225 – 1322Ig-like C2-type 6Add BLAST98
Domaini1333 – 1422Ig-like C2-type 7Add BLAST90

Keywords - Domaini

Immunoglobulin domain, Repeat

Phylogenomic databases

eggNOGiENOG410IJ5G Eukaryota
ENOG410ZSRR LUCA
HOGENOMiHOG000293283
HOVERGENiHBG004977
PhylomeDBiQ02173

Family and domain databases

CDDicd00063 FN3, 5 hits
Gene3Di2.60.40.10, 12 hits
InterProiView protein in InterPro
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2
PfamiView protein in Pfam
PF00041 fn3, 5 hits
PF07679 I-set, 3 hits
SMARTiView protein in SMART
SM00060 FN3, 5 hits
SM00409 IG, 5 hits
SM00408 IGc2, 4 hits
SUPFAMiSSF48726 SSF48726, 7 hits
SSF49265 SSF49265, 3 hits
PROSITEiView protein in PROSITE
PS50853 FN3, 5 hits
PS50835 IG_LIKE, 4 hits

Sequencei

Sequence statusi: Complete.

Q02173-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSVAVPFYQ RRHKHFDQSY RNIQTRYVLE EYAARKAASR QAAHYESTGL
60 70 80 90 100
GKTTCRLCAR RARSLAHEAM QESRKRTHEQ KSHASDEKRI KFASELSSLE
110 120 130 140 150
REIHMARHHA REQLDRLAIQ RMVEENMALE RHVVEEKISR APEILVRLRS
160 170 180 190 200
HTVWEKMSVR LCFTVQGFPS PVVQWYKNEE LITPASDPAK YSVENKYGVH
210 220 230 240 250
VLHINRADFD DSATYSAVAT NIHGQASTNC AVVVRRFRES EEPHPAGIMP
260 270 280 290 300
FHLPLSYDVC FTHFDVQFLE KFGVTFATEG ETLTLKCSVL VTPELKRLRP
310 320 330 340 350
RAEWYRDDVL IKDSKWTKLY FGEGQAALSF THLNKDDEGL YTLRMVTKGG
360 370 380 390 400
VNECSAFLFV RDADALIAGA PGAPMDVKCH DANRDYVIVT WKPPNTTSQN
410 420 430 440 450
PVIGYFVDKC EVGLENWVQC NDAPVKICKY PVTGLYEGRS YIFRVRAVNS
460 470 480 490 500
AGISRPSRVS EPVAALDPVD LERTQTVHVD EGRKIVISKD DLEGDIQIPG
510 520 530 540 550
PPTNVHASEI SKTYVVLSWD PPVPRGREPL TYFIEKSMVG SGSWQRVNAQ
560 570 580 590 600
VAVKSPRYAV FDLAEGKPYV FRVLSANKHG ISDPSEITEP IQPQDIVVVP
610 620 630 640 650
SAPGRVVATR NTKTSVVVQW DKPKHEENLY GYYIDYSVVG SNQWEPANHK
660 670 680 690 700
PINYNRFVVH GLETGEQYIF RVKAVNAVGF SENSQESEAI KVQAALTCPS
710 720 730 740 750
YPHGITLLNC DGHSMTLGWK APKYSGGSPI LGYYIDKREA NHKNWHEVNS
760 770 780 790 800
SVISRTIYTV EDLTEDAFYE FKIAAANVVG IGHPSDPSEH FKCKAWTMPE
810 820 830 840 850
PGPAYDLTVC EVRNTSLVLL WKAPVYEGKS PITGYLVDYK EVDTEDWITA
860 870 880 890 900
NEKPTSHRYF KVTDLHQGHT YVFKVRAVND AGVGKSSEIS EPVFVEASPG
910 920 930 940 950
TKEIFSGVDE EGNIYLGFEC KEATDASHFL WGKSYEEIED SDKFKIETKG
960 970 980 990 1000
DHSKLYFKHP DKSDLGTYCI SVSDTDGVSS SFVLDEEELE RLMTLSNEIK
1010 1020 1030 1040 1050
NPTIPLKSEL AYEVLDKGEV RFWIQAESLS PNSTYRFVIN DKEVENGDRH
1060 1070 1080 1090 1100
KISCDHSNGI IEMVMDKFTI DNEGTYTVQI QDGKAKNQSS LVLIGDAFKA
1110 1120 1130 1140 1150
ILAESELQRK EFLRKQGPHF SEFLYWEVTE ECEVLLACKI ANTKKETVFK
1160 1170 1180 1190 1200
WYRNGSGIDV DEAPDLQKGE CHLTVPKLSR KDEGVYKATL SDDRGHDVST
1210 1220 1230 1240 1250
LELSGKVYND IILALSRVSG KTASPLKILC TEEGIRLQCF LKYYNEEMKV
1260 1270 1280 1290 1300
TWSHRESKIS SGEKMKIGGG EDVAWLQITE PTEKDKGNYT FEIFSDKESF
1310 1320 1330 1340 1350
KRTLDLSGQA FDDALTEFQR LKAAAFAEKN RGKVIGGLPD VVTIMDGKTL
1360 1370 1380 1390 1400
NLTCTVFGNP DPEVVWFKND KALELNEHYL VSLEQGKYAS LTIKGVTSED
1410 1420 1430 1440 1450
SGKYSIYVKN KYGGETVDVT VSVYRHGEKI PEVNQGQLAK PRLIPPSSST
Length:1,450
Mass (Da):163,401
Last modified:June 1, 1994 - v1
Checksum:iE313C7D39FE6CAC7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D11474 mRNA Translation: BAA02033.1
PIRiA44027
RefSeqiNP_990466.1, NM_205135.1
UniGeneiGga.4216

Genome annotation databases

GeneIDi396034
KEGGigga:396034

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D11474 mRNA Translation: BAA02033.1
PIRiA44027
RefSeqiNP_990466.1, NM_205135.1
UniGeneiGga.4216

3D structure databases

ProteinModelPortaliQ02173
SMRiQ02173
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000026310

Proteomic databases

PaxDbiQ02173
PRIDEiQ02173

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi396034
KEGGigga:396034

Organism-specific databases

CTDi9172

Phylogenomic databases

eggNOGiENOG410IJ5G Eukaryota
ENOG410ZSRR LUCA
HOGENOMiHOG000293283
HOVERGENiHBG004977
PhylomeDBiQ02173

Miscellaneous databases

PROiPR:Q02173

Family and domain databases

CDDicd00063 FN3, 5 hits
Gene3Di2.60.40.10, 12 hits
InterProiView protein in InterPro
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2
PfamiView protein in Pfam
PF00041 fn3, 5 hits
PF07679 I-set, 3 hits
SMARTiView protein in SMART
SM00060 FN3, 5 hits
SM00409 IG, 5 hits
SM00408 IGc2, 4 hits
SUPFAMiSSF48726 SSF48726, 7 hits
SSF49265 SSF49265, 3 hits
PROSITEiView protein in PROSITE
PS50853 FN3, 5 hits
PS50835 IG_LIKE, 4 hits
ProtoNetiSearch...

Entry informationi

Entry nameiMPSF_CHICK
AccessioniPrimary (citable) accession number: Q02173
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: November 7, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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