UniProtKB - Q02086 (SP2_HUMAN)

BLAST

>sp|Q02086|SP2_HUMAN Transcription factor Sp2 OS=Homo sapiens OX=9606 GN=SP2 PE=1 SV=3
MSDPQTSMAATAAVSPSDYLQPAASTTQDSQPSPLALLAATCSKIGPPAVEAAVTPPAPP
QPTPRKLVPIKPAPLPLSPGKNSFGILSSKGNILQIQGSQLSASYPGGQLVFAIQNPTMI
NKGTRSNANIQYQAVPQIQASNSQTIQVQPNLTNQIQIIPGTNQAIITPSPSSHKPVPIK
PAPIQKSSTTTTPVQSGANVVKLTGGGGNVTLTLPVNNLVNASDTGAPTQLLTESPPTPL
SKTNKKARKKSLPASQPPVAVAEQVETVLIETTADNIIQAGNNLLIVQSPGGGQPAVVQQ
VQVVPPKAEQQQVVQIPQQALRVVQAASATLPTVPQKPSQNFQIQAAEPTPTQVYIRTPS
GEVQTVLVQDSPPATAAATSNTTCSSPASRAPHLSGTSKKHSAAILRKERPLPKIAPAGS
IISLNAAQLAAAAQAMQTININGVQVQGVPVTITNTGGQQQLTVQNVSGNNLTISGLSPT
QIQLQMEQALAGETQPGEKRRRMACTCPNCKDGEKRSGEQGKKKHVCHIPDCGKTFRKTS
LLRAHVRLHTGERPFVCNWFFCGKRFTRSDELQRHARTHTGDKRFECAQCQKRFMRSDHL
TKHYKTHLVTKNL

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History
Entry version 170 (10 Oct 2018)
Sequence version 3 (12 Dec 2006)
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Protein

Transcription factor Sp2

Gene

SP2

Organism

Homo sapiens (Human)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites.

Regions

Feature key	Position(s)	DescriptionActions	Length
Zinc fingerⁱ	525 – 549	C2H2-type 1PROSITE-ProRule annotationAdd BLAST	25
Zinc fingerⁱ	555 – 579	C2H2-type 2PROSITE-ProRule annotationAdd BLAST	25
Zinc fingerⁱ	585 – 607	C2H2-type 3PROSITE-ProRule annotationAdd BLAST	23

GO - Molecular functionⁱ

histone deacetylase binding
Source: BHF-UCL
Inferred from physical interactionⁱ
- 17827154
metal ion binding Source: UniProtKB-KW
RNA polymerase II proximal promoter sequence-specific DNA binding
Source: NTNU_SB
Inferred from direct assayⁱ
- 10744779
RNA polymerase II transcription factor activity, sequence-specific DNA binding Source: NTNU_SB
transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
Source: NTNU_SB
Inferred from direct assayⁱ
- 10744779

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

immune response
Source: ProtInc
Traceable author statementⁱ
- 1341900
multicellular organism growth Source: InterPro
negative regulation of transcription by RNA polymerase II
Source: NTNU_SB
Inferred from direct assayⁱ
- 10744779
regulation of transcription by RNA polymerase II
Source: ProtInc
Traceable author statementⁱ
- 1341900
transcription, DNA-templated Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Activator, DNA-binding
Biological process	Transcription, Transcription regulation
Ligand	Metal-binding, Zinc

Enzyme and pathway databases

SignaLinkⁱ	Q02086
SIGNORⁱ	Q02086

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Transcription factor Sp2
Gene namesⁱ	Name:SP2 Synonyms:KIAA0048
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 17

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000167182.12
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:11207 SP2
MIMⁱ	601801 gene
neXtProtⁱ	NX_Q02086

Keywords - Cellular componentⁱ

Nucleus

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	6668
Open Targets More...OpenTargetsⁱ	ENSG00000167182
PharmGKBⁱ	PA36044

Polymorphism and mutation databases

BioMutaⁱ	SP2
DMDMⁱ	119370531

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000047140	1 – 613	Transcription factor Sp2Add BLAST		613

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Modified residueⁱ	78	PhosphoserineCombined sources		1

Keywords - PTMⁱ

Phosphoprotein

Proteomic databases

EPDⁱ	Q02086
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q02086
PaxDbⁱ	Q02086
PeptideAtlas More...PeptideAtlasⁱ	Q02086
PRIDEⁱ	Q02086
ProteomicsDBⁱ	58047 58048 [Q02086-2]

PTM databases

iPTMnetⁱ	Q02086
PhosphoSitePlusⁱ	Q02086

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000167182 Expressed in 217 organ(s), highest expression level in heart left ventricle
CleanExⁱ	HS_SP2
ExpressionAtlasⁱ	Q02086 baseline and differential
Genevisibleⁱ	Q02086 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	CAB010245 HPA003357

HPAⁱ

CAB010245
HPA003357

Interactionⁱ

Binary interactionsⁱ

With	Entry	#Exp.	IntAct
BANP	Q8N9N5	4	EBI-8651703,EBI-744695
FHL2	Q14192	3	EBI-8651703,EBI-701903
MCM7	P33993	3	EBI-8651703,EBI-355924

GO - Molecular functionⁱ

histone deacetylase binding
Source: BHF-UCL
Inferred from physical interactionⁱ
- 17827154

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	112551, 14 interactors
IntActⁱ	Q02086, 8 interactors
Molecular INTeraction database More...MINTⁱ	Q02086
STRINGⁱ	9606.ENSP00000365931

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q02086
SMRⁱ	Q02086
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the Sp1 C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature key	Position(s)	DescriptionActions	Length
Zinc fingerⁱ	525 – 549	C2H2-type 1PROSITE-ProRule annotationAdd BLAST	25
Zinc fingerⁱ	555 – 579	C2H2-type 2PROSITE-ProRule annotationAdd BLAST	25
Zinc fingerⁱ	585 – 607	C2H2-type 3PROSITE-ProRule annotationAdd BLAST	23

Keywords - Domainⁱ

Repeat, Zinc-finger

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118984
HOGENOMⁱ	HOG000234295
HOVERGENⁱ	HBG008933
InParanoidⁱ	Q02086
KEGG Orthology (KO) More...KOⁱ	K09192
OMAⁱ	KRRMACT
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0HX6
PhylomeDBⁱ	Q02086
TreeFamⁱ	TF350150

Family and domain databases

InterProⁱ	View protein in InterPro IPR030451 SP2_TF IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
PANTHERⁱ	PTHR23235:SF1 PTHR23235:SF1, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 3 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 3 hits
SUPFAMⁱ	SSF57667 SSF57667, 3 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 3 hits PS50157 ZINC_FINGER_C2H2_2, 3 hits

Sequences (2+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 2 described isoforms and 5 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: Q02086-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MSDPQTSMAA TAAVSPSDYL QPAASTTQDS QPSPLALLAA TCSKIGPPAV 
        60         70         80         90        100
EAAVTPPAPP QPTPRKLVPI KPAPLPLSPG KNSFGILSSK GNILQIQGSQ 
       110        120        130        140        150
LSASYPGGQL VFAIQNPTMI NKGTRSNANI QYQAVPQIQA SNSQTIQVQP 
       160        170        180        190        200
NLTNQIQIIP GTNQAIITPS PSSHKPVPIK PAPIQKSSTT TTPVQSGANV 
       210        220        230        240        250
VKLTGGGGNV TLTLPVNNLV NASDTGAPTQ LLTESPPTPL SKTNKKARKK 
       260        270        280        290        300
SLPASQPPVA VAEQVETVLI ETTADNIIQA GNNLLIVQSP GGGQPAVVQQ 
       310        320        330        340        350
VQVVPPKAEQ QQVVQIPQQA LRVVQAASAT LPTVPQKPSQ NFQIQAAEPT 
       360        370        380        390        400
PTQVYIRTPS GEVQTVLVQD SPPATAAATS NTTCSSPASR APHLSGTSKK 
       410        420        430        440        450
HSAAILRKER PLPKIAPAGS IISLNAAQLA AAAQAMQTIN INGVQVQGVP 
       460        470        480        490        500
VTITNTGGQQ QLTVQNVSGN NLTISGLSPT QIQLQMEQAL AGETQPGEKR 
       510        520        530        540        550
RRMACTCPNC KDGEKRSGEQ GKKKHVCHIP DCGKTFRKTS LLRAHVRLHT 
       560        570        580        590        600
GERPFVCNWF FCGKRFTRSD ELQRHARTHT GDKRFECAQC QKRFMRSDHL 
       610 
TKHYKTHLVT KNL

Length:613

Mass (Da):64,900

Last modified:December 12, 2006 - v3

Checksum:ⁱDEE6BFCAE3405793

Isoform 2 (identifier: Q02086-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-7: Missing.

« Hide

        10         20         30         40         50
MAATAAVSPS DYLQPAASTT QDSQPSPLAL LAATCSKIGP PAVEAAVTPP 
        60         70         80         90        100
APPQPTPRKL VPIKPAPLPL SPGKNSFGIL SSKGNILQIQ GSQLSASYPG 
       110        120        130        140        150
GQLVFAIQNP TMINKGTRSN ANIQYQAVPQ IQASNSQTIQ VQPNLTNQIQ 
       160        170        180        190        200
IIPGTNQAII TPSPSSHKPV PIKPAPIQKS STTTTPVQSG ANVVKLTGGG 
       210        220        230        240        250
GNVTLTLPVN NLVNASDTGA PTQLLTESPP TPLSKTNKKA RKKSLPASQP 
       260        270        280        290        300
PVAVAEQVET VLIETTADNI IQAGNNLLIV QSPGGGQPAV VQQVQVVPPK 
       310        320        330        340        350
AEQQQVVQIP QQALRVVQAA SATLPTVPQK PSQNFQIQAA EPTPTQVYIR 
       360        370        380        390        400
TPSGEVQTVL VQDSPPATAA ATSNTTCSSP ASRAPHLSGT SKKHSAAILR 
       410        420        430        440        450
KERPLPKIAP AGSIISLNAA QLAAAAQAMQ TININGVQVQ GVPVTITNTG 
       460        470        480        490        500
GQQQLTVQNV SGNNLTISGL SPTQIQLQME QALAGETQPG EKRRRMACTC 
       510        520        530        540        550
PNCKDGEKRS GEQGKKKHVC HIPDCGKTFR KTSLLRAHVR LHTGERPFVC 
       560        570        580        590        600
NWFFCGKRFT RSDELQRHAR THTGDKRFEC AQCQKRFMRS DHLTKHYKTH 

LVTKNL

Show »

Length:606

Mass (Da):64,153

Checksum:ⁱA27C6D460D36E186

Computationally mapped potential isoform sequencesⁱ

There are 5 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

Q9BRW5	Q9BRW5_HUMAN	SP2 protein SP2 protein (Transcription factor Sp2)	SP2	249	Annotation score:
A0A1B0GVH1	A0A1B0GVH1_HUMAN	Transcription factor Sp2 Transcription factor Sp2	SP2	97	Annotation score:
A0A1B0GV29	A0A1B0GV29_HUMAN	Transcription factor Sp2 Transcription factor Sp2	SP2	53	Annotation score:
A0A1B0GTK3	A0A1B0GTK3_HUMAN	Transcription factor Sp2 Transcription factor Sp2	SP2	43	Annotation score:
A0A286YFJ7	A0A286YFJ7_HUMAN	Transcription factor Sp2 Transcription factor Sp2	SP2	88	Annotation score:

Sequence cautionⁱ

The sequence AAH16680 differs from that shown. Reason: Erroneous initiation.Curated

The sequence AAH33814 differs from that shown. Reason: Erroneous initiation.Curated

The sequence BAA05923 differs from that shown. Reason: Erroneous initiation.Curated

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_022021	1 – 7	Missing in isoform 2. 1 Publication		7

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	D28588 mRNA Translation: BAA05923.2 Different initiation. AC018521 Genomic DNA No translation available. CH471109 Genomic DNA Translation: EAW94785.1 BC016680 mRNA Translation: AAH16680.1 Different initiation. BC033814 mRNA Translation: AAH33814.1 Different initiation. M97190 mRNA Translation: AAA36629.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS11521.2 [Q02086-1]
PIRⁱ	A44489
NCBI Reference Sequences More...RefSeqⁱ	NP_003101.3, NM_003110.5 [Q02086-1]
UniGeneⁱ	Hs.514276

Genome annotation databases

Ensemblⁱ	ENST00000376741; ENSP00000365931; ENSG00000167182 [Q02086-1]
GeneIDⁱ	6668
KEGGⁱ	hsa:6668
UCSC genome browser More...UCSCⁱ	uc002imk.3 human [Q02086-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q02086	SP2 isoform 1		PONAB		613	UniRef100_Q02086
Sp2 transcription factor		GORGO		613
Q02086-2	Uncharacterized protein		PONAB		606	UniRef100_K7EV25
UPI0005D03EBC		HUMAN		717

Protein	Similar proteins		Species	Score	Length	Source
Q02086	Transcription factor Sp2		BOVIN		613	UniRef90_Q02086
Transcription factor Sp2		MOUSE		612
SP2 isoform 1		PONAB		613
Sp2 transcription factor		GORGO		613
Uncharacterized protein		ICTTR		615
+174
Q02086-2	Sp2 transcription factor		CANLF		624	UniRef90_J9NRJ6
Uncharacterized protein		PAPAN		676
Uncharacterized protein		MACMU		673
Uncharacterized protein		RHIRO		664
Uncharacterized protein		MACFA		637
+60

Protein	Similar proteins		Species	Score	Length	Source
Q02086	Transcription factor Sp2		BOVIN		613	UniRef50_Q02086
Transcription factor Sp2		MOUSE		612
SP2 isoform 1		PONAB		613
Sp2 transcription factor		GORGO		613
Uncharacterized protein		AOTNA		615
+408

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	D28588 mRNA Translation: BAA05923.2 Different initiation. AC018521 Genomic DNA No translation available. CH471109 Genomic DNA Translation: EAW94785.1 BC016680 mRNA Translation: AAH16680.1 Different initiation. BC033814 mRNA Translation: AAH33814.1 Different initiation. M97190 mRNA Translation: AAA36629.1
CCDSⁱ	CCDS11521.2 [Q02086-1]
PIRⁱ	A44489
RefSeqⁱ	NP_003101.3, NM_003110.5 [Q02086-1]
UniGeneⁱ	Hs.514276

3D structure databases

ProteinModelPortalⁱ	Q02086
SMRⁱ	Q02086
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	112551, 14 interactors
IntActⁱ	Q02086, 8 interactors
MINTⁱ	Q02086
STRINGⁱ	9606.ENSP00000365931

PTM databases

iPTMnetⁱ	Q02086
PhosphoSitePlusⁱ	Q02086

Polymorphism and mutation databases

BioMutaⁱ	SP2
DMDMⁱ	119370531

Proteomic databases

EPDⁱ	Q02086
MaxQBⁱ	Q02086
PaxDbⁱ	Q02086
PeptideAtlasⁱ	Q02086
PRIDEⁱ	Q02086
ProteomicsDBⁱ	58047 58048 [Q02086-2]

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	6668
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000376741; ENSP00000365931; ENSG00000167182 [Q02086-1]
GeneIDⁱ	6668
KEGGⁱ	hsa:6668
UCSCⁱ	uc002imk.3 human [Q02086-1]

Organism-specific databases

CTDⁱ	6668
DisGeNETⁱ	6668
EuPathDBⁱ	HostDB:ENSG00000167182.12
GeneCardsⁱ	SP2
HGNCⁱ	HGNC:11207 SP2
HPAⁱ	CAB010245 HPA003357
MIMⁱ	601801 gene
neXtProtⁱ	NX_Q02086
OpenTargetsⁱ	ENSG00000167182
PharmGKBⁱ	PA36044
HUGEⁱ	Search...
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
GeneTreeⁱ	ENSGT00760000118984
HOGENOMⁱ	HOG000234295
HOVERGENⁱ	HBG008933
InParanoidⁱ	Q02086
KOⁱ	K09192
OMAⁱ	KRRMACT
OrthoDBⁱ	EOG091G0HX6
PhylomeDBⁱ	Q02086
TreeFamⁱ	TF350150

Enzyme and pathway databases

SignaLinkⁱ	Q02086
SIGNORⁱ	Q02086

Miscellaneous databases

ChiTaRSⁱ	SP2 human
GeneWikiⁱ	Sp2_transcription_factor
GenomeRNAiⁱ	6668
Protein Ontology More...PROⁱ	PR:Q02086
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000167182 Expressed in 217 organ(s), highest expression level in heart left ventricle
CleanExⁱ	HS_SP2
ExpressionAtlasⁱ	Q02086 baseline and differential
Genevisibleⁱ	Q02086 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR030451 SP2_TF IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
PANTHERⁱ	PTHR23235:SF1 PTHR23235:SF1, 1 hit
Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 3 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 3 hits
SUPFAMⁱ	SSF57667 SSF57667, 3 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 3 hits PS50157 ZINC_FINGER_C2H2_2, 3 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	SP2_HUMAN
Accessionⁱ	Q02086Primary (citable) accession number: Q02086 Secondary accession number(s): A6NK74
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
	Last sequence update:	December 12, 2006
	Last modified:	October 10, 2018
	This is version 170 of the entry and version 3 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human chromosome 17
Human chromosome 17: entries, gene names and cross-references to MIM
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q02086 (SP2_HUMAN)

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Transcription factor Sp2

SP2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Keywords - Domaini

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Sequence cautionⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ