UniProtKB - Q01835 (P60_LISGR)
Protein
Probable endopeptidase p60
Gene
iap
Organism
Listeria grayi (Listeria murrayi)
Status
Functioni
This major extracellular protein may be involved in the invasion of non-professional phagocytic cells by Listeria.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 423 | NucleophilePROSITE-ProRule annotation | 1 | |
Active sitei | 473 | Proton acceptorPROSITE-ProRule annotation | 1 | |
Active sitei | 485 | PROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- cysteine-type peptidase activity Source: UniProtKB-KW
Keywordsi
Molecular function | Hydrolase, Protease, Thiol protease |
Names & Taxonomyi
Protein namesi | Recommended name: Probable endopeptidase p60 (EC:3.4.-.-)Alternative name(s): Invasion-associated protein p60 |
Gene namesi | Name:iap |
Organismi | Listeria grayi (Listeria murrayi) |
Taxonomic identifieri | 1641 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Bacillales › Listeriaceae › Listeria |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 27 | By similarityAdd BLAST | 27 | |
ChainiPRO_0000019757 | 28 – 511 | Probable endopeptidase p60Add BLAST | 484 |
Proteomic databases
PRIDEi | Q01835 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 28 – 71 | LysM 1PROSITE-ProRule annotationAdd BLAST | 44 | |
Domaini | 78 – 142 | SH3bPROSITE-ProRule annotationAdd BLAST | 65 | |
Domaini | 175 – 218 | LysM 2PROSITE-ProRule annotationAdd BLAST | 44 | |
Domaini | 297 – 341 | LysM 3PROSITE-ProRule annotationAdd BLAST | 45 | |
Domaini | 393 – 511 | NlpC/P60PROSITE-ProRule annotationAdd BLAST | 119 |
Domaini
LysM domains are thought to be involved in peptidoglycan binding.
Sequence similaritiesi
Keywords - Domaini
Repeat, SignalFamily and domain databases
CDDi | cd00118, LysM, 3 hits |
Gene3Di | 3.10.350.10, 3 hits |
InterProi | View protein in InterPro IPR018392, LysM_dom IPR036779, LysM_dom_sf IPR000064, NLP_P60_dom IPR038765, Papain-like_cys_pep_sf IPR003646, SH3-like_bac-type |
Pfami | View protein in Pfam PF01476, LysM, 3 hits PF00877, NLPC_P60, 1 hit PF08239, SH3_3, 1 hit |
SMARTi | View protein in SMART SM00257, LysM, 3 hits SM00287, SH3b, 1 hit |
SUPFAMi | SSF54001, SSF54001, 1 hit |
PROSITEi | View protein in PROSITE PS51782, LYSM, 3 hits PS51935, NLPC_P60, 1 hit PS51781, SH3B, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q01835-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNMKKATIVS AAGIAVTAFA APSVVSANTV VVASGDTLWG IASKTGTTVD
60 70 80 90 100
QLKQLNKLDS DRIVPGQKLT IKEVAAQKVE KSVSATWLNV RHAPDANEKI
110 120 130 140 150
LTSLKGRTVV KVESSEANGW NKISFDNGKT GYVNGKYLSD AKVAAPVVTK
160 170 180 190 200
AVTHKAEAKV AATSTHAVKV DTNASTYKVK SGDTIWALSV KYGVPVQKLI
210 220 230 240 250
EWNNLSSSSI YVGQTIAVKE AAAKAAPTTV KQAAPAKVAP KQEVKQTAPA
260 270 280 290 300
KQEQAKPAAK ETVKPAVSKP KAATPAPTAK PAVEQKASTP AVDTNAATYK
310 320 330 340 350
VQNGDSLGKI ASLFKVSVAD LTNWNNLNAT ITIYAGQELS VKASAAKPKP
360 370 380 390 400
AAPAKPAVSK PATSTPAKVT PTNTTNNSTP TTNVNNNTSQ SSSASFSALY
410 420 430 440 450
AEAKKHLGKP YTWGARGPST FDCSGFTSYV FNQVGLSLSG NSATQYANST
460 470 480 490 500
KISESQAQPG DLVFFNYGSG IAHVGIYIGG GQMIDAQDNG VSIDNIHGNG
510
WGQYLVGFGR V
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M80352 Genomic DNA Translation: AAA25285.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M80352 Genomic DNA Translation: AAA25285.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PRIDEi | Q01835 |
Family and domain databases
CDDi | cd00118, LysM, 3 hits |
Gene3Di | 3.10.350.10, 3 hits |
InterProi | View protein in InterPro IPR018392, LysM_dom IPR036779, LysM_dom_sf IPR000064, NLP_P60_dom IPR038765, Papain-like_cys_pep_sf IPR003646, SH3-like_bac-type |
Pfami | View protein in Pfam PF01476, LysM, 3 hits PF00877, NLPC_P60, 1 hit PF08239, SH3_3, 1 hit |
SMARTi | View protein in SMART SM00257, LysM, 3 hits SM00287, SH3b, 1 hit |
SUPFAMi | SSF54001, SSF54001, 1 hit |
PROSITEi | View protein in PROSITE PS51782, LYSM, 3 hits PS51935, NLPC_P60, 1 hit PS51781, SH3B, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | P60_LISGR | |
Accessioni | Q01835Primary (citable) accession number: Q01835 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 1, 1993 |
Last sequence update: | April 1, 1993 | |
Last modified: | December 2, 2020 | |
This is version 84 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Documents
- SIMILARITY comments
Index of protein domains and families - Peptidase families
Classification of peptidase families and list of entries