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Entry version 105 (12 Aug 2020)
Sequence version 2 (01 Nov 1995)
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Protein

Ferrioxamine receptor

Gene

foxA

Organism
Yersinia enterocolitica
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Ferrioxamine binding and uptake, in association with the TonB protein.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionReceptor
Biological processIon transport, Iron transport, Transport
LigandIron

Protein family/group databases

Transport Classification Database

More...
TCDBi
1.B.14.1.17, the outer membrane receptor (omr) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ferrioxamine receptor
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:foxA
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiYersinia enterocolitica
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri630 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeYersinia

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei29 – 37Beta strandedSequence analysis9
Transmembranei65 – 73Beta strandedSequence analysis9
Transmembranei91 – 99Beta strandedSequence analysis9
Transmembranei106 – 114Beta strandedSequence analysis9
Transmembranei137 – 145Beta strandedSequence analysis9
Transmembranei152 – 160Beta strandedSequence analysis9
Transmembranei180 – 188Beta strandedSequence analysis9
Transmembranei194 – 202Beta strandedSequence analysis9
Transmembranei208 – 216Beta strandedSequence analysis9
Transmembranei259 – 267Beta strandedSequence analysis9
Transmembranei271 – 279Beta strandedSequence analysis9
Transmembranei293 – 301Beta strandedSequence analysis9
Transmembranei309 – 317Beta strandedSequence analysis9
Transmembranei353 – 361Beta strandedSequence analysis9
Transmembranei370 – 378Beta strandedSequence analysis9
Transmembranei427 – 435Beta strandedSequence analysis9
Transmembranei443 – 451Beta strandedSequence analysis9
Transmembranei476 – 484Beta strandedSequence analysis9
Transmembranei491 – 499Beta strandedSequence analysis9
Transmembranei517 – 525Beta strandedSequence analysis9
Transmembranei531 – 539Beta strandedSequence analysis9
Transmembranei555 – 563Beta strandedSequence analysis9
Transmembranei567 – 575Beta strandedSequence analysis9
Transmembranei579 – 587Beta strandedSequence analysis9
Transmembranei610 – 618Beta strandedSequence analysis9
Transmembranei624 – 632Beta strandedSequence analysis9
Transmembranei649 – 657Beta strandedSequence analysis9
Transmembranei671 – 679Beta strandedSequence analysis9
Transmembranei684 – 692Beta strandedSequence analysis9
Transmembranei702 – 710Beta strandedSequence analysis9

Keywords - Cellular componenti

Cell outer membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 26Sequence analysisAdd BLAST26
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000003475527 – 710Ferrioxamine receptorAdd BLAST684

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
1443113.LC20_04880

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q01674

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi28 – 35TonB box8
Motifi693 – 710TonB C-terminal boxAdd BLAST18

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TonB-dependent receptor family.Curated

Keywords - Domaini

Signal, TonB box, Transmembrane, Transmembrane beta strand

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG4774, Bacteria

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.170.130.10, 1 hit
2.40.170.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012910, Plug_dom
IPR037066, Plug_dom_sf
IPR039423, TonB-dep_rcpt
IPR000531, TonB-dep_rcpt_b-brl
IPR036942, TonB_rcpt_b-brl_sf
IPR010917, TonB_rcpt_CS
IPR010105, TonB_sidphr_rcpt

The PANTHER Classification System

More...
PANTHERi
PTHR32552, PTHR32552, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07715, Plug, 1 hit
PF00593, TonB_dep_Rec, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01783, TonB-siderophor, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00430, TONB_DEPENDENT_REC_1, 1 hit
PS01156, TONB_DEPENDENT_REC_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q01674-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFSAFIIKRS AILCSLAMFI PLASIADDTI EVTAKAGHEA DLPTSGYTAT
60 70 80 90 100
TTKGATKTDQ PLILTAQSVS VVTRQQMDDQ NVATVNQALN YTPGVFTGFS
110 120 130 140 150
GGATRYDTVA LRGFHGGDVN NTFLDGLRLL SDGGSYNVLQ VDPWFLERID
160 170 180 190 200
VIKGPSSALY GQSIPGGVVM MTSKRPQFTS EGHFRLTAGN NNTQVAAFDY
210 220 230 240 250
TDAISEHWAF RLTGITRNSD TMYDHQREER YAIAPSLLWQ PDENTSLLLR
260 270 280 290 300
ANLQKDPSGG YHSAVPADGS IYGQKLSRGF FDGESNHNVF KRWQQIYSYE
310 320 330 340 350
FSHKFDDVWS FRQNASYTHS NTQLEQVYQG GWNSDRTLMN RYYSGEDSSL
360 370 380 390 400
NAFAVDNQLE ADLRTAAVKH KVLLGVDFQK FRNNLRSDSA YATPLNPYTG
410 420 430 440 450
VSGGSTLYSD YLLTTPGINT SYLSRRYEQS GVYLQDEMTL DNWHLNLSGR
460 470 480 490 500
YDRMKTENIN NTANSTDERT DNHASGRASL LYSFDSGISP YVSYSQAITP
510 520 530 540 550
SLFPDAQQKL LKPMTSEQYE VGIIYQPPGS TSLYSAALYD LTQNDVANRA
560 570 580 590 600
VPATYYVPAG KVNSQGLELE ARSQISDRLS VIAGYTYNRV KFKDAIDGND
610 620 630 640 650
GNTPVLAPSN MASLWAQYEA GYGINVGAGI RYIGKQWADD ANTLRVPSYT
660 670 680 690 700
LGDASVRADL GTWAASLKGA FVQLNVNNIA DKKYVAACYS TSYCYWGAER
710
SVQATVGYDF
Length:710
Mass (Da):78,383
Last modified:November 1, 1995 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i82EB6EC1546900B8
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X60447 Genomic DNA Translation: CAA42975.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S22673

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X60447 Genomic DNA Translation: CAA42975.1
PIRiS22673

3D structure databases

SMRiQ01674
ModBaseiSearch...

Protein-protein interaction databases

STRINGi1443113.LC20_04880

Protein family/group databases

TCDBi1.B.14.1.17, the outer membrane receptor (omr) family

Phylogenomic databases

eggNOGiCOG4774, Bacteria

Family and domain databases

Gene3Di2.170.130.10, 1 hit
2.40.170.20, 1 hit
InterProiView protein in InterPro
IPR012910, Plug_dom
IPR037066, Plug_dom_sf
IPR039423, TonB-dep_rcpt
IPR000531, TonB-dep_rcpt_b-brl
IPR036942, TonB_rcpt_b-brl_sf
IPR010917, TonB_rcpt_CS
IPR010105, TonB_sidphr_rcpt
PANTHERiPTHR32552, PTHR32552, 1 hit
PfamiView protein in Pfam
PF07715, Plug, 1 hit
PF00593, TonB_dep_Rec, 1 hit
TIGRFAMsiTIGR01783, TonB-siderophor, 1 hit
PROSITEiView protein in PROSITE
PS00430, TONB_DEPENDENT_REC_1, 1 hit
PS01156, TONB_DEPENDENT_REC_2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFOXA_YEREN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q01674
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: November 1, 1995
Last modified: August 12, 2020
This is version 105 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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