Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 165 (05 Jun 2019)
Sequence version 4 (06 Jul 2016)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein

Protein couch potato

Gene

cpo

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a role in the development or function of the peripheral nervous system by regulating the processing of nervous system-specific transcripts.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • mRNA binding Source: FlyBase

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein, RNA-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein couch potato
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:cpo
ORF Names:CG43738
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0263995 cpo

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Mutations cause hypoactive behavior in adults.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000815201 – 606Protein couch potatoAdd BLAST606

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q01617

PRoteomics IDEntifications database

More...
PRIDEi
Q01617

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in neural precursors and their daughter cells in the embryonic peripheral nervous system. Less abundant in a number of glial cells in the peripheral and central nervous systems and also present at low levels in the developing gut.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0263995 Expressed in 39 organ(s), highest expression level in antenna

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q01617 DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
69919, 8 interactors

Protein interaction database and analysis system

More...
IntActi
Q01617, 1 interactor

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0303307

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q01617

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati91 – 9515
Repeati109 – 11325
Repeati114 – 11835
Repeati122 – 12645
Repeati128 – 13255
Repeati134 – 13865
Repeati159 – 16375
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini442 – 524RRMPROSITE-ProRule annotationAdd BLAST83

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni91 – 1647 X 5 AA approximate repeats of P-V-S-V-PAdd BLAST74

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi81 – 105Nuclear localization signalAdd BLAST25

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi11 – 22Poly-AlaAdd BLAST12
Compositional biasi56 – 59Poly-Ser4
Compositional biasi140 – 184His-richAdd BLAST45
Compositional biasi185 – 285Gln-richAdd BLAST101
Compositional biasi290 – 296Poly-Ser7
Compositional biasi308 – 392Ala-richAdd BLAST85
Compositional biasi402 – 410Poly-Ser9
Compositional biasi571 – 606Ala-richAdd BLAST36

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1457 Eukaryota
ENOG410XSBT LUCA

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q01617

Family and domain databases

Conserved Domains Database

More...
CDDi
cd12684 RRM_cpo, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.70.330, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR034788 Cpo_RRM
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00076 RRM_1, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00360 RRM, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54928 SSF54928, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50102 RRM, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q01617-4) [UniParc]FASTAAdd to basket
Also known as: NImported, UImported, YImported

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MLGSHHQLLI AATAAAAAAA AAEPQLQLQH LLPAAPTTPA VISNPINSIG
60 70 80 90 100
PINQISSSSH PSNNNQQAVF EKAITISSIA IKRRPTLPQT PASAPQVLSP
110 120 130 140 150
SPKRQCAAAV SVLPVTVPVP VPVSVPLPVS VPVPVSVKGH PISHTHQIAH
160 170 180 190 200
THQISHSHPI SHPHHHQLSF AHPTQFAAAV AAHHQQQQQQ QAQQQQQAVQ
210 220 230 240 250
QQQQQAVQQQ QVAYAVAASP QLQQQQQQQQ HRLAQFNQAA AAALLNQHLQ
260 270 280 290 300
QQHQAQQQQH QAQQQSLAHY GGYQLHRYAP QQQQQHILLS SGSSSSKHNS
310 320 330 340 350
NNNSNTSAGA ASAAVPIATS VAAVPTTGGS LPDSPAHESH SHESNSATAS
360 370 380 390 400
APTTPSPAGS VTSAAPTATA TAAAAGSAAA TAAATGTPAT SAVSDSNNNL
410 420 430 440 450
NSSSSSNSNS NAIMENQMAL APLGLSQSMD SVNTASNEEE VRTLFVSGLP
460 470 480 490 500
MDAKPRELYL LFRAYEGYEG SLLKVTSKNG KTASPVGFVT FHTRAGAEAA
510 520 530 540 550
KQDLQGVRFD PDMPQTIRLE FAKSNTKVSK PKPQPNTATT ASHPALMHPL
560 570 580 590 600
TGHLGGPFFP GGPELWHHPL AYSAAAAAEL PGAAALQHAT LVHPALHPQV

PVRSYL
Note: No experimental confirmation available.
Length:606
Mass (Da):63,296
Last modified:July 6, 2016 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB27A0F7F0E774FCE
GO
Isoform 2 (identifier: Q01617-6) [UniParc]FASTAAdd to basket
Also known as: TImported, VImported

The sequence of this isoform differs from the canonical sequence as follows:
     505-505: Q → QQ

Note: No experimental confirmation available.
Show »
Length:607
Mass (Da):63,424
Checksum:iE872AE6E903C30E9
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0B4KGD8A0A0B4KGD8_DROME
Couch potato, isoform W
cpo 1824, 3603, 5339, 6015, BcDNA:AT31405
606Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0B4KGV8A0A0B4KGV8_DROME
Couch potato, isoform O
cpo 1824, 3603, 5339, 6015, BcDNA:AT31405
748Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0B4KHP4A0A0B4KHP4_DROME
Couch potato, isoform P
cpo 1824, 3603, 5339, 6015, BcDNA:AT31405
841Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0B4KHB6A0A0B4KHB6_DROME
Couch potato, isoform Q
cpo 1824, 3603, 5339, 6015, BcDNA:AT31405
762Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAF55483 differs from that shown. Reason: Erroneous gene model prediction. Stop codon readthrough.Curated
The sequence AAM76197 differs from that shown. Unusual initiator. The initiator methionine is coded by a non-canonical CTC leucine codon.Curated
The sequence AAM76197 differs from that shown. Reason: Erroneous translation. Wrong choice of frame.Curated
The sequence AAN71324 differs from that shown. Unusual initiator. The initiator methionine is coded by a non-canonical CTC leucine codon.Curated
The sequence AAN71324 differs from that shown. Reason: Frameshift at positions 111 and 181.Curated
The sequence AAN71324 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence AAX52960 differs from that shown. Reason: Erroneous gene model prediction. Stop codon readthrough.Curated
The sequence CAA78663 differs from that shown. Unusual initiator. The initiator methionine is coded by a non-canonical CTC leucine codon.Curated
The sequence CAA78663 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAA78664 differs from that shown. Unusual initiator. The initiator methionine is coded by a non-canonical CTC leucine codon.Curated
The sequence CAA78664 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAA78696 differs from that shown. Unusual initiator. The initiator methionine is coded by a non-canonical CTC leucine codon.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti14A → D in CAA78663 (PubMed:1427076).Curated1
Sequence conflicti14A → D in CAA78664 (PubMed:1427076).Curated1
Sequence conflicti14A → D in CAA78696 (PubMed:1427076).Curated1
Sequence conflicti169S → T in CAA78663 (PubMed:1427076).Curated1
Sequence conflicti169S → T in CAA78664 (PubMed:1427076).Curated1
Sequence conflicti169S → T in CAA78696 (PubMed:1427076).Curated1
Sequence conflicti302N → T in CAA78663 (PubMed:1427076).Curated1
Sequence conflicti302N → T in CAA78664 (PubMed:1427076).Curated1
Sequence conflicti302N → T in CAA78696 (PubMed:1427076).Curated1
Sequence conflicti310A → G in CAA78663 (PubMed:1427076).Curated1
Sequence conflicti310A → G in CAA78664 (PubMed:1427076).Curated1
Sequence conflicti310A → G in CAA78696 (PubMed:1427076).Curated1
Sequence conflicti587 – 588QH → HS in CAA78696 (PubMed:1427076).Curated2

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural varianti347A → V in strain: DPF; induces a high-diapause phenotype. 1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_058445505Q → QQ in isoform 2. 1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
Z14311 Genomic DNA Translation: CAA78663.1 Sequence problems.
Z14312 Genomic DNA Translation: CAA78664.1 Sequence problems.
Z14974 Genomic DNA Translation: CAA78696.1 Sequence problems.
AE014297 Genomic DNA Translation: AAF55483.6 Sequence problems.
AE014297 Genomic DNA Translation: AAF55484.6
AE014297 Genomic DNA Translation: AAF55485.6
AE014297 Genomic DNA Translation: AAN13754.5
AE014297 Genomic DNA Translation: AAX52960.2 Sequence problems.
AE014297 Genomic DNA Translation: AAX52961.2
AE014297 Genomic DNA Translation: ACZ94936.2
AY129455 mRNA Translation: AAM76197.1 Sequence problems.
BT001569 mRNA Translation: AAN71324.1 Frameshift.

Protein sequence database of the Protein Information Resource

More...
PIRi
A46230
S24761

NCBI Reference Sequences

More...
RefSeqi
NP_001014631.3, NM_001014631.3 [Q01617-6]
NP_001014632.3, NM_001014632.4
NP_001163640.2, NM_001170169.3 [Q01617-6]
NP_001262691.1, NM_001275762.1 [Q01617-4]
NP_001262692.1, NM_001275763.1 [Q01617-4]
NP_524844.6, NM_080105.4 [Q01617-4]
NP_732282.6, NM_169781.4
NP_732283.5, NM_169782.3 [Q01617-4]
NP_732284.5, NM_169783.4 [Q01617-4]

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
45840

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG43738

UCSC genome browser

More...
UCSCi
CG31243-RB d. melanogaster
CG31243-RG d. melanogaster
CG31243-RH d. melanogaster

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z14311 Genomic DNA Translation: CAA78663.1 Sequence problems.
Z14312 Genomic DNA Translation: CAA78664.1 Sequence problems.
Z14974 Genomic DNA Translation: CAA78696.1 Sequence problems.
AE014297 Genomic DNA Translation: AAF55483.6 Sequence problems.
AE014297 Genomic DNA Translation: AAF55484.6
AE014297 Genomic DNA Translation: AAF55485.6
AE014297 Genomic DNA Translation: AAN13754.5
AE014297 Genomic DNA Translation: AAX52960.2 Sequence problems.
AE014297 Genomic DNA Translation: AAX52961.2
AE014297 Genomic DNA Translation: ACZ94936.2
AY129455 mRNA Translation: AAM76197.1 Sequence problems.
BT001569 mRNA Translation: AAN71324.1 Frameshift.
PIRiA46230
S24761
RefSeqiNP_001014631.3, NM_001014631.3 [Q01617-6]
NP_001014632.3, NM_001014632.4
NP_001163640.2, NM_001170169.3 [Q01617-6]
NP_001262691.1, NM_001275762.1 [Q01617-4]
NP_001262692.1, NM_001275763.1 [Q01617-4]
NP_524844.6, NM_080105.4 [Q01617-4]
NP_732282.6, NM_169781.4
NP_732283.5, NM_169782.3 [Q01617-4]
NP_732284.5, NM_169783.4 [Q01617-4]

3D structure databases

SMRiQ01617
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi69919, 8 interactors
IntActiQ01617, 1 interactor
STRINGi7227.FBpp0303307

Proteomic databases

PaxDbiQ01617
PRIDEiQ01617

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi45840
KEGGidme:Dmel_CG43738
UCSCiCG31243-RB d. melanogaster
CG31243-RG d. melanogaster
CG31243-RH d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
130749
FlyBaseiFBgn0263995 cpo

Phylogenomic databases

eggNOGiKOG1457 Eukaryota
ENOG410XSBT LUCA
InParanoidiQ01617

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
cpo fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
45840

Protein Ontology

More...
PROi
PR:Q01617

Gene expression databases

BgeeiFBgn0263995 Expressed in 39 organ(s), highest expression level in antenna
GenevisibleiQ01617 DM

Family and domain databases

CDDicd12684 RRM_cpo, 1 hit
Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR034788 Cpo_RRM
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PfamiView protein in Pfam
PF00076 RRM_1, 1 hit
SMARTiView protein in SMART
SM00360 RRM, 1 hit
SUPFAMiSSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCPO_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q01617
Secondary accession number(s): A4V319
, E1JIN7, Q59DW5, Q59DW6, Q8IGV9, Q8MQI9, Q9VED9, Q9VEE1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: July 6, 2016
Last modified: June 5, 2019
This is version 165 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again