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1 to 25 of 25  Show
  1. 1
    "Amplification and direct sequencing of a cDNA encoding human cytosolic 3-hydroxy-3-methylglutaryl-coenzyme A synthase."
    Russ A.P., Ruzicka V., Maerz W., Appelhans H., Gross W.
    Biochim. Biophys. Acta 1132:329-331(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Category: Sequences.
    Tissue: Fibroblast.
    Source: UniProtKB/Swiss-Prot (reviewed).
  2. 2
    "Human cytoplasmic 3-hydroxy-3-methylglutaryl coenzyme A synthase: expression, purification, and characterization of recombinant wild-type and Cys129 mutant enzymes."
    Rokosz L.L., Boulton D.A., Butkiewicz E.A., Sanyal G., Cueto M.A., Lachance P.A., Hermes J.D.
    Arch. Biochem. Biophys. 312:1-13(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], CHARACTERIZATION, MUTAGENESIS.
    Category: Pathology & Biotech, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  3. 3
    "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
    Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S., Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y., Phelan M., Farmer A.
    Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  4. 4
    "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Category: Sequences.
    Tissue: Placenta.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 12931 other entries.

  5. 5
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  6. 6
    "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Category: Sequences.
    Tissue: Lung.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 50474 other entries.

  7. 7
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-476 AND SER-495, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: PTM / Processing, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 8731 other entries.

  8. 8
    "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 5365 and mapped to 17 other entries.

  9. 9
    "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-495, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: PTM / Processing, Sequences.
    Tissue: Leukemic T-cell.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 5550 other entries.

  10. 10
    "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
    Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M.
    Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-46 AND LYS-273, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: PTM / Processing, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 3089 other entries.

  11. 11
    "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-495, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: PTM / Processing, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 7260 and mapped to 5 other entries.

  12. 12
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 18101 other entries.

  13. 13
    "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-4 AND SER-495, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: PTM / Processing, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 5561 other entries.

  14. 14
    "Toward a comprehensive characterization of a human cancer cell phosphoproteome."
    Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J., Mohammed S.
    J. Proteome Res. 12:260-271(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-4; SER-495 AND SER-516, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: PTM / Processing, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 13321 other entries.

  15. 15
    "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
    Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.
    J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-495, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: PTM / Processing, Sequences.
    Tissue: Liver.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 11541 other entries.

  16. 16
    "Crystal structures of human HMG-CoA synthase isoforms provide insights into inherited ketogenesis disorders and inhibitor design."
    Shafqat N., Turnbull A., Zschocke J., Oppermann U., Yue W.W.
    J. Mol. Biol. 398:497-506(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 16-470 OF HOMODIMER IN COMPLEX WITH COENZYME A, SUBSTRATE-BINDING SITES, REGION, SUBUNIT.
    Category: Function, Interaction, Structure, Family & Domains.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 4 other entries.

  17. 17
    "Transcriptional activities of nuclear SREBP-1a, -1c, and -2 to different target promoters of lipogenic and cholesterogenic genes."
    Amemiya-Kudo M., Shimano H., Hasty A.H., Yahagi N., Yoshikawa T., Matsuzaka T., Okazaki H., Tamura Y., Iizuka Y., Ohashi K., Osuga J., Harada K., Gotoda T., Sato R., Kimura S., Ishibashi S., Yamada N.
    J. Lipid Res. 43:1220-1235(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: PathwayImported.
    Source: Reactome:R-HSA-191329.

    This publication is mapped to 26 other entries.

  18. 18
    Category: Interaction.
    Source: IntAct:Q01581.

    This publication is mapped to 1880 other entries.

  19. 19
    "Covalent capture of kinase-specific phosphopeptides reveals Cdk1-cyclin B substrates."
    Blethrow J.D., Glavy J.S., Morgan D.O., Shokat K.M.
    Proc. Natl. Acad. Sci. U.S.A. 105:1442-1447(2008) [PubMed] [Europe PMC] [Abstract]
    Category: PTM / Processing.
    Source: PhosphoSitePlus:Q01581.

    This publication is mapped to 67 other entries.

  20. 20
    "Polymorphisms in the estrogen receptor 1 and vitamin C and matrix metalloproteinase gene families are associated with susceptibility to lymphoma."
    Skibola C.F., Bracci P.M., Halperin E., Nieters A., Hubbard A., Paynter R.A., Skibola D.R., Agana L., Becker N., Tressler P., Forrest M.S., Sankararaman S., Conde L., Holly E.A., Smith M.T.
    PLoS ONE 3:e2816-e2816(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Observational study of gene-disease association. (HuGE Navigator)Imported.
    Source: GeneRIF:3157.

    This publication is mapped to 2528 other entries.

  21. 21
    "Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations."
    Lu Y., Dolle M.E., Imholz S., van 't Slot R., Verschuren W.M., Wijmenga C., Feskens E.J., Boer J.M.
    J. Lipid Res. 49:2582-2589(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech.
    Annotation: Not Associated with METABOLIC: plasma HDL cholesterol (HDL-C) levels.Imported, Observational study of gene-disease association. (HuGE Navigator)Imported.
    Source: GAD:581015, GeneRIF:3157.

    This publication is mapped to 1520 other entries.

  22. 22
    "Transcriptional regulation of HMG-CoA synthase and HMG-CoA reductase genes by human ACBP."
    Vock C., Doring F., Nitz I.
    Cell. Physiol. Biochem. 22:515-524(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: ACBP is a transcriptional regulator of the HMGCS1 and HMGCR genes encoding rate-limiting enzymes of cholesterol synthesis pathway.Imported, PathwayImported.
    Source: Reactome:R-HSA-191329, GeneRIF:3157.

    This publication is mapped to 31 other entries.

  23. 23
    "The human-bacterial pathogen protein interaction networks of Bacillus anthracis, Francisella tularensis, and Yersinia pestis."
    Dyer M.D., Neff C., Dufford M., Rivera C.G., Shattuck D., Bassaganya-Riera J., Murali T.M., Sobral B.W.
    PLoS ONE 5:e12089-e12089(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Source: IntAct:Q01581.

    This publication is mapped to 4924 other entries.

  24. 24
    "Inhibition of HCV replication by oxysterol-binding protein-related protein 4 (ORP4) through interaction with HCV NS5B and alteration of lipid droplet formation."
    Park I.W., Ndjomou J., Wen Y., Liu Z., Ridgway N.D., Kao C.C., He J.J.
    PLoS ONE 8:e75648-e75648(2013) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Source: IntAct:Q01581.

    This publication is mapped to 7 other entries.

  25. 25
    "HMG-CoA synthase 1 is a synthetic lethal partner of BRAFV600E in human cancers."
    Zhao L., Fan J., Xia S., Pan Y., Liu S., Qian G., Qian Z., Kang H.B., Arbiser J.L., Pollack B.P., Kudchadkar R.R., Lawson D.H., Rossi M., Abdel-Wahab O., Merghoub T., Khoury H.J., Khuri F.R., Boise L.H.
    Lin R.
    J. Biol. Chem. 292:10142-10152(2017) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Data suggest that HMGCS1 (HMG-CoA synthase 1) signals through ketogenesis/acetoacetate to promote cell proliferation and BRAF(V600E)-dependent MEK1 activation in BRAF(V600E)-positive melanoma and colon cancer cells; HMGCS1 co-localizes with HMGCL (HMG-CoA lyase) and BRAF(V600E) in cytosol of melanoma and colon cancer cells. (BRAF = proto-oncogene protein B-raf)Imported.
    Source: GeneRIF:3157.

    This publication is mapped to 11 other entries.

1 to 25 of 25  Show
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