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UniProtKB - Q01464 (MIND_BACSU)
Protein
Septum site-determining protein MinD
Gene
minD
Organism
Bacillus subtilis (strain 168)
Status
Functioni
ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings (By similarity).
By similarityRegions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 11 – 18 | ATPBy similarity | 8 |
GO - Molecular functioni
- ATP binding Source: GO_Central
- ATP hydrolysis activity Source: GO_Central
GO - Biological processi
- division septum assembly Source: UniProtKB-KW
- negative regulation of cell division Source: GO_Central
Keywordsi
Biological process | Cell cycle, Cell division, Septation |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
BioCyci | BSUB:BSU27990-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Septum site-determining protein MinDAlternative name(s): Cell division inhibitor MinD |
Gene namesi | Name:minD Synonyms:divIVB Ordered Locus Names:BSU27990 |
Organismi | Bacillus subtilis (strain 168) |
Taxonomic identifieri | 224308 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
Cytosol
- cytosol Source: GO_Central
Plasma Membrane
- cytoplasmic side of plasma membrane Source: GO_Central
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000201964 | 1 – 268 | Septum site-determining protein MinDAdd BLAST | 268 |
Proteomic databases
jPOSTi | Q01464 |
PaxDbi | Q01464 |
PRIDEi | Q01464 |
Interactioni
Subunit structurei
Interacts with MinC and FtsZ (By similarity).
Interacts with MinJ.
By similarity2 PublicationsBinary interactionsi
Protein-protein interaction databases
IntActi | Q01464, 8 interactors |
MINTi | Q01464 |
STRINGi | 224308.BSU27990 |
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
eggNOGi | COG2894, Bacteria |
InParanoidi | Q01464 |
OMAi | CESAKAY |
PhylomeDBi | Q01464 |
Family and domain databases
Gene3Di | 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR002586, CobQ/CobB/MinD/ParA_Nub-bd_dom IPR010223, MinD IPR025501, MinD_FleN IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF01656, CbiA, 1 hit |
PIRSFi | PIRSF003092, MinD, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR01968, minD_bact, 1 hit |
i Sequence
Sequence statusi: Complete.
Q01464-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGEAIVITSG KGGVGKTTTS ANLGTALAIL GKRVCLVDTD IGLRNLDVVM
60 70 80 90 100
GLENRIIYDL VDVVEGRCKM HQALVKDKRF DDLLYLMPAA QTSDKTAVAP
110 120 130 140 150
EQIKNMVQEL KQEFDYVIID CPAGIEQGYK NAVSGADKAI VVTTPEISAV
160 170 180 190 200
RDADRIIGLL EQEENIEPPR LVVNRIRNHL MKNGDTMDID EIVQHLSIDL
210 220 230 240 250
LGIVADDDEV IKASNHGEPI AMDPKNRASI AYRNIARRIL GESVPLQVLE
260
EQNKGMMAKI KSFFGVRS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M95582 Genomic DNA Translation: AAA22609.1 Z15113 Genomic DNA Translation: CAA78818.1 M96343 Genomic DNA Translation: AAA22401.1 AL009126 Genomic DNA Translation: CAB14759.1 |
PIRi | S31205, G45239 |
RefSeqi | NP_390677.1, NC_000964.3 WP_004398624.1, NZ_JNCM01000036.1 |
Genome annotation databases
EnsemblBacteriai | CAB14759; CAB14759; BSU_27990 |
GeneIDi | 937499 |
KEGGi | bsu:BSU27990 |
PATRICi | fig|224308.179.peg.3041 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M95582 Genomic DNA Translation: AAA22609.1 Z15113 Genomic DNA Translation: CAA78818.1 M96343 Genomic DNA Translation: AAA22401.1 AL009126 Genomic DNA Translation: CAB14759.1 |
PIRi | S31205, G45239 |
RefSeqi | NP_390677.1, NC_000964.3 WP_004398624.1, NZ_JNCM01000036.1 |
3D structure databases
AlphaFoldDBi | Q01464 |
SMRi | Q01464 |
ModBasei | Search... |
Protein-protein interaction databases
IntActi | Q01464, 8 interactors |
MINTi | Q01464 |
STRINGi | 224308.BSU27990 |
Proteomic databases
jPOSTi | Q01464 |
PaxDbi | Q01464 |
PRIDEi | Q01464 |
Genome annotation databases
EnsemblBacteriai | CAB14759; CAB14759; BSU_27990 |
GeneIDi | 937499 |
KEGGi | bsu:BSU27990 |
PATRICi | fig|224308.179.peg.3041 |
Phylogenomic databases
eggNOGi | COG2894, Bacteria |
InParanoidi | Q01464 |
OMAi | CESAKAY |
PhylomeDBi | Q01464 |
Enzyme and pathway databases
BioCyci | BSUB:BSU27990-MONOMER |
Family and domain databases
Gene3Di | 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR002586, CobQ/CobB/MinD/ParA_Nub-bd_dom IPR010223, MinD IPR025501, MinD_FleN IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF01656, CbiA, 1 hit |
PIRSFi | PIRSF003092, MinD, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR01968, minD_bact, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | MIND_BACSU | |
Accessioni | Q01464Primary (citable) accession number: Q01464 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 1, 1993 |
Last sequence update: | July 1, 1993 | |
Last modified: | May 25, 2022 | |
This is version 142 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families