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Protein

Arsenical resistance operon repressor

Gene

arsR

Organism
Staphylococcus xylosus
Status
Reviewed-Annotation score: -Protein predictedi

Functioni

Transcriptional repressor for the ars operon. ArsR is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsR is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenate (As(V)).

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi32 – 51H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding, Repressor
Biological processArsenical resistance, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Arsenical resistance operon repressor
Gene namesi
Name:arsR
Encoded oniPlasmid pSX2670 Publication
OrganismiStaphylococcus xylosus
Taxonomic identifieri1288 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001606151 – 104Arsenical resistance operon repressorAdd BLAST104

Structurei

3D structure databases

ProteinModelPortaliQ01256
SMRiQ01256
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 92HTH arsR-typePROSITE-ProRule annotationAdd BLAST92

Family and domain databases

CDDicd00090 HTH_ARSR, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR011991 ArsR-like_HTH
IPR018334 ArsR_HTH
IPR001845 HTH_ArsR_DNA-bd_dom
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF01022 HTH_5, 1 hit
PRINTSiPR00778 HTHARSR
SMARTiView protein in SMART
SM00418 HTH_ARSR, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS00846 HTH_ARSR_1, 1 hit
PS50987 HTH_ARSR_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q01256-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSYKELSTIL KVLSDPSRLE ILDLLSCGEL CACDLLEHFQ FSQPTLSHHM
60 70 80 90 100
KSLVDNELVT TRKNGNKHMY QLNHEFLDYI NQNLDIINTS DQGCACKNMK

SGEC
Length:104
Mass (Da):11,866
Last modified:April 1, 1993 - v1
Checksum:i17B68444B7B344A7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M80565 Genomic DNA Translation: AAA27587.1
PIRiA41902

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M80565 Genomic DNA Translation: AAA27587.1
PIRiA41902

3D structure databases

ProteinModelPortaliQ01256
SMRiQ01256
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

CDDicd00090 HTH_ARSR, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR011991 ArsR-like_HTH
IPR018334 ArsR_HTH
IPR001845 HTH_ArsR_DNA-bd_dom
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF01022 HTH_5, 1 hit
PRINTSiPR00778 HTHARSR
SMARTiView protein in SMART
SM00418 HTH_ARSR, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS00846 HTH_ARSR_1, 1 hit
PS50987 HTH_ARSR_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiARSR_STAXY
AccessioniPrimary (citable) accession number: Q01256
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 1, 1993
Last sequence update: April 1, 1993
Last modified: September 12, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Plasmid
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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