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UniProtKB - Q00994 (BEX3_HUMAN)

Protein

Protein BEX3

Gene

BEX3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.By similarity

Miscellaneous

Binds transition metals.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

View the complete GO annotation on QuickGO ...

GO - Biological processi

View the complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processApoptosis
LigandMetal-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-205025 NADE modulates death signalling

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein BEX3Curated
Alternative name(s):
Brain-expressed X-linked protein 3Imported
Nerve growth factor receptor-associated protein 1
Ovarian granulosa cell 13.0 kDa protein HGR74
p75NTR-associated cell death executor
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:BEX3Imported
Synonyms:DXS6984E, NADE, NGFRAP1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		HostDB:ENSG00000166681.13

Human Gene Nomenclature Database

More...HGNCi		HGNC:13388 BEX3

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		300361 gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q00994

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		27018

Open Targets

More...OpenTargetsi		ENSG00000166681

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA31616

Polymorphism and mutation databases

Domain mapping of disease mutations (DMDM)

More...DMDMi		547642

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000966881 – 111Protein BEX3Add BLAST111

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Ubiquitinated. Degraded by the proteasome (By similarity).By similarity

Keywords - PTMi

Ubl conjugation

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q00994

PeptideAtlas

More...PeptideAtlasi		Q00994

PRoteomics IDEntifications database

More...PRIDEi		Q00994

ProteomicsDB human proteome resource

More...ProteomicsDBi		57900

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000166681 Expressed in 242 organ(s), highest expression level in cerebellar vermis

CleanEx database of gene expression profiles

More...CleanExi		HS_NGFRAP1

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q00994 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA018886

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Self-associates. Binds to the DEATH domain of p75NTR/NGFR. Interacts with 14-3-3 epsilon (YWHAE). Interacts with DIABLO/SMAC.By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		117956, 19 interactors

Protein interaction database and analysis system

More...IntActi		Q00994, 34 interactors

Molecular INTeraction database

More...MINTi		Q00994

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000299872

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...ProteinModelPortali		Q00994

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q00994

Database of comparative protein structure models

More...ModBasei		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni68 – 111Interaction with 14-3-3 epsilonBy similarityAdd BLAST44
Regioni68 – 93Interaction with p75NTR/NGFRBy similarityAdd BLAST26

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi77 – 87Nuclear export signalBy similarityAdd BLAST11

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The nuclear export signal is required for export from the nucleus and the interactions with itself and p75NTR/NGFR.By similarity

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the BEX family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG410JCIT Eukaryota
ENOG41113TP LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00940000153412

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000236300

The HOVERGEN Database of Homologous Vertebrate Genes

More...HOVERGENi		HBG080240

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q00994

KEGG Orthology (KO)

More...KOi		K12465

Identification of Orthologs from Complete Genome Data

More...OMAi		PMQNREE

Database of Orthologous Groups

More...OrthoDBi		EOG091G146U

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q00994

TreeFam database of animal gene trees

More...TreeFami		TF337909

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR007623 BEX
IPR021156 TF_A-like/BEX

Pfam protein domain database

More...Pfami		View protein in Pfam
PF04538 BEX, 1 hit

PIRSF; a whole-protein classification database

More...PIRSFi		PIRSF008633 BEX, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q00994-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MANIHQENEE MEQPMQNGEE DRPLGGGEGH QPAGNRRGQA RRLAPNFRWA 
        60         70         80         90        100
IPNRQINDGM GGDGDDMEIF MEEMREIRRK LRELQLRNCL RILMGELSNH 
       110 
HDHHDEFCLM P
Length:111
Mass (Da):12,959
Last modified:June 1, 1994 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i29AA0573282C933E
GO
Isoform 2 (identifier: Q00994-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-10: Missing.

Note: No experimental confirmation available.
Show »
Length:101
Mass (Da):11,762
Checksum:iED263FF37D8E838F
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0463431 – 10Missing in isoform 2. 1 Publication10

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
M38188 mRNA Translation: AAA63232.1
AF187064 mRNA Translation: AAF75129.1
AY833562 mRNA Translation: AAX40680.1
AK315371 mRNA Translation: BAG37764.1
EL953547 Genomic DNA No translation available.
AL606763 Genomic DNA No translation available.
CH471190 Genomic DNA Translation: EAW54710.1
CH471190 Genomic DNA Translation: EAW54712.1
BC003190 mRNA Translation: AAH03190.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS14508.1 [Q00994-1]
CCDS14509.1 [Q00994-2]

Protein sequence database of the Protein Information Resource

More...PIRi		C35826

NCBI Reference Sequences

More...RefSeqi		NP_055195.1, NM_014380.2 [Q00994-1]
NP_996798.1, NM_206915.2 [Q00994-1]
NP_996800.1, NM_206917.2 [Q00994-2]

UniGene gene-oriented nucleotide sequence clusters

More...UniGenei		Hs.448588

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000361298; ENSP00000354843; ENSG00000166681 [Q00994-2]
ENST00000372634; ENSP00000361717; ENSG00000166681 [Q00994-2]
ENST00000372635; ENSP00000361718; ENSG00000166681 [Q00994-1]
ENST00000372645; ENSP00000361728; ENSG00000166681 [Q00994-1]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		27018

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:27018

UCSC genome browser

More...UCSCi		uc004ekh.5 human [Q00994-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M38188 mRNA Translation: AAA63232.1
AF187064 mRNA Translation: AAF75129.1
AY833562 mRNA Translation: AAX40680.1
AK315371 mRNA Translation: BAG37764.1
EL953547 Genomic DNA No translation available.
AL606763 Genomic DNA No translation available.
CH471190 Genomic DNA Translation: EAW54710.1
CH471190 Genomic DNA Translation: EAW54712.1
BC003190 mRNA Translation: AAH03190.1
CCDSiCCDS14508.1 [Q00994-1]
CCDS14509.1 [Q00994-2]
PIRiC35826
RefSeqiNP_055195.1, NM_014380.2 [Q00994-1]
NP_996798.1, NM_206915.2 [Q00994-1]
NP_996800.1, NM_206917.2 [Q00994-2]
UniGeneiHs.448588

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1SA6model-A1-111[»]
ProteinModelPortaliQ00994
SMRiQ00994
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi117956, 19 interactors
IntActiQ00994, 34 interactors
MINTiQ00994
STRINGi9606.ENSP00000299872

Polymorphism and mutation databases

DMDMi547642

Proteomic databases

PaxDbiQ00994
PeptideAtlasiQ00994
PRIDEiQ00994
ProteomicsDBi57900

Protocols and materials databases

The DNASU plasmid repository

More...DNASUi		27018
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000361298; ENSP00000354843; ENSG00000166681 [Q00994-2]
ENST00000372634; ENSP00000361717; ENSG00000166681 [Q00994-2]
ENST00000372635; ENSP00000361718; ENSG00000166681 [Q00994-1]
ENST00000372645; ENSP00000361728; ENSG00000166681 [Q00994-1]
GeneIDi27018
KEGGihsa:27018
UCSCiuc004ekh.5 human [Q00994-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		27018
DisGeNETi27018
EuPathDBiHostDB:ENSG00000166681.13

GeneCards: human genes, protein and diseases

More...GeneCardsi		BEX3
HGNCiHGNC:13388 BEX3
HPAiHPA018886
MIMi300361 gene
neXtProtiNX_Q00994
OpenTargetsiENSG00000166681
PharmGKBiPA31616

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG410JCIT Eukaryota
ENOG41113TP LUCA
GeneTreeiENSGT00940000153412
HOGENOMiHOG000236300
HOVERGENiHBG080240
InParanoidiQ00994
KOiK12465
OMAiPMQNREE
OrthoDBiEOG091G146U
PhylomeDBiQ00994
TreeFamiTF337909

Enzyme and pathway databases

ReactomeiR-HSA-205025 NADE modulates death signalling

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		BEX3 human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		NGFRAP1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		27018

Protein Ontology

More...PROi		PR:Q00994

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000166681 Expressed in 242 organ(s), highest expression level in cerebellar vermis
CleanExiHS_NGFRAP1
GenevisibleiQ00994 HS

Family and domain databases

InterProiView protein in InterPro
IPR007623 BEX
IPR021156 TF_A-like/BEX
PfamiView protein in Pfam
PF04538 BEX, 1 hit
PIRSFiPIRSF008633 BEX, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiBEX3_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q00994
Secondary accession number(s): B2RD17
, D3DXA3, Q5JQT4, Q5JQT5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: December 5, 2018
This is version 160 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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