UniProtKB - Q00985 (ACCO1_MALDO)
Protein
1-aminocyclopropane-1-carboxylate oxidase 1
Gene
N/A
Organism
Malus domestica (Apple) (Pyrus malus)
Status
Functioni
Catalytic activityi
- 1-aminocyclopropane-1-carboxylate + L-ascorbate + O2 = CO2 + ethene + 2 H2O + hydrogen cyanide + L-dehydroascorbateEC:1.14.17.4
Cofactori
: ethylene biosynthesis via S-adenosyl-L-methionine Pathwayi
This protein is involved in step 2 of the subpathway that synthesizes ethylene from S-adenosyl-L-methionine.Proteins known to be involved in the 2 steps of the subpathway in this organism are:
- 1-aminocyclopropane-1-carboxylate synthase (ACS-1)
- 1-aminocyclopropane-1-carboxylate oxidase 2 (ACO2), 1-aminocyclopropane-1-carboxylate oxidase 1
View all proteins of this organism that are known to be involved in the subpathway that synthesizes ethylene from S-adenosyl-L-methionine, the pathway ethylene biosynthesis via S-adenosyl-L-methionine and in Alkene biosynthesis.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 177 | IronPROSITE-ProRule annotation | 1 | |
Metal bindingi | 179 | IronPROSITE-ProRule annotation | 1 | |
Metal bindingi | 234 | IronPROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- 1-aminocyclopropane-1-carboxylate oxidase activity Source: UniProtKB-EC
- L-ascorbic acid binding Source: UniProtKB-KW
- metal ion binding Source: UniProtKB-KW
GO - Biological processi
- ethylene biosynthetic process Source: UniProtKB-UniPathway
- fruit ripening Source: UniProtKB-KW
Keywordsi
Molecular function | Oxidoreductase |
Biological process | Ethylene biosynthesis, Fruit ripening |
Ligand | Iron, Metal-binding, Vitamin C |
Enzyme and pathway databases
BioCyci | MetaCyc:MONOMER-16249 |
BRENDAi | 1.14.17.4, 3165 |
SABIO-RKi | Q00985 |
UniPathwayi | UPA00384;UER00563 |
Names & Taxonomyi
Protein namesi | Recommended name: 1-aminocyclopropane-1-carboxylate oxidase 1 (EC:1.14.17.4)Short name: ACC oxidase 1 Alternative name(s): Ethylene-forming enzyme Short name: EFE PAE12 Protein AP4 |
Organismi | Malus domestica (Apple) (Pyrus malus) |
Taxonomic identifieri | 3750 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › fabids › Rosales › Rosaceae › Amygdaloideae › Maleae › Malus |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000067265 | 1 – 314 | 1-aminocyclopropane-1-carboxylate oxidase 1Add BLAST | 314 |
Proteomic databases
PRIDEi | Q00985 |
Expressioni
Developmental stagei
Expressed during fruit ripening.
Inductioni
By ethylene and wounding.
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 153 – 253 | Fe2OG dioxygenasePROSITE-ProRule annotationAdd BLAST | 101 |
Sequence similaritiesi
Belongs to the iron/ascorbate-dependent oxidoreductase family.Curated
Family and domain databases
Gene3Di | 2.60.120.330, 1 hit |
InterProi | View protein in InterPro IPR026992, DIOX_N IPR027443, IPNS-like IPR005123, Oxoglu/Fe-dep_dioxygenase |
Pfami | View protein in Pfam PF03171, 2OG-FeII_Oxy, 1 hit PF14226, DIOX_N, 1 hit |
PROSITEi | View protein in PROSITE PS51471, FE2OG_OXY, 1 hit |
i Sequence
Sequence statusi: Complete.
Q00985-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MATFPVVDLS LVNGEERAAT LEKINDACEN WGFFELVNHG MSTELLDTVE
60 70 80 90 100
KMTKDHYKKT MEQRFKEMVA AKGLDDVQSE IHDLDWESTF FLRHLPSSNI
110 120 130 140 150
SEIPDLEEEY RKTMKEFAVE LEKLAEKLLD LLCENLGLEK GYLKKVFYGS
160 170 180 190 200
KGPNFGTKVS NYPPCPKPDL IKGLRAHSDA GGIILLFQDD KVSGLQLLKD
210 220 230 240 250
GEWVDVPPMH HSIVINLGDQ IEVITNGKYK SVMHRVIAQS DGTRMSIASF
260 270 280 290 300
YNPGNDSFIS PAPAVLEKKT EDAPTYPKFV FDDYMKLYSG LKFQAKEPRF
310
EAMKAKESTP VATA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X61390 mRNA Translation: CAA43662.1 M81794 mRNA Translation: AAA33412.1 Y14005 Genomic DNA Translation: CAA74328.1 AF030859 Genomic DNA Translation: AAC36461.1 |
PIRi | S22513 |
Genome annotation databases
EnsemblPlantsi | mRNA:MD10G0280000; mRNA:MD10G0280000; MD10G0280000 |
Gramenei | mRNA:MD10G0280000; mRNA:MD10G0280000; MD10G0280000 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X61390 mRNA Translation: CAA43662.1 M81794 mRNA Translation: AAA33412.1 Y14005 Genomic DNA Translation: CAA74328.1 AF030859 Genomic DNA Translation: AAC36461.1 |
PIRi | S22513 |
3D structure databases
SMRi | Q00985 |
ModBasei | Search... |
Chemistry databases
BindingDBi | Q00985 |
Proteomic databases
PRIDEi | Q00985 |
Genome annotation databases
EnsemblPlantsi | mRNA:MD10G0280000; mRNA:MD10G0280000; MD10G0280000 |
Gramenei | mRNA:MD10G0280000; mRNA:MD10G0280000; MD10G0280000 |
Enzyme and pathway databases
UniPathwayi | UPA00384;UER00563 |
BioCyci | MetaCyc:MONOMER-16249 |
BRENDAi | 1.14.17.4, 3165 |
SABIO-RKi | Q00985 |
Family and domain databases
Gene3Di | 2.60.120.330, 1 hit |
InterProi | View protein in InterPro IPR026992, DIOX_N IPR027443, IPNS-like IPR005123, Oxoglu/Fe-dep_dioxygenase |
Pfami | View protein in Pfam PF03171, 2OG-FeII_Oxy, 1 hit PF14226, DIOX_N, 1 hit |
PROSITEi | View protein in PROSITE PS51471, FE2OG_OXY, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ACCO1_MALDO | |
Accessioni | Q00985Primary (citable) accession number: Q00985 Secondary accession number(s): O24063 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 1, 1993 |
Last sequence update: | April 1, 1993 | |
Last modified: | October 7, 2020 | |
This is version 102 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Direct protein sequencingDocuments
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families