UniProtKB - Q00944 (FAK1_CHICK)
Focal adhesion kinase 1
PTK2
Functioni
Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development, embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart development. Regulates axon growth and neuronal cell migration, axon branching and synapse formation; required for normal development of the nervous system. Plays a role in osteogenesis and differentiation of osteoblasts. Functions in integrin signal transduction, but also in signaling downstream of numerous growth factor receptors, G-protein coupled receptors (GPCR), ephrin receptors, netrin receptors and LDL receptors. Forms multisubunit signaling complexes with SRC and SRC family members upon activation; this leads to the phosphorylation of additional tyrosine residues, creating binding sites for scaffold proteins, effectors and substrates. Regulates numerous signaling pathways. Promotes activation of phosphatidylinositol 3-kinase and the AKT1 signaling cascade. Promotes activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling cascade. Promotes localized and transient activation of guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs), and thereby modulates the activity of Rho family GTPases. Signaling via CAS family members mediates activation of RAC1. Regulates P53/TP53 activity and stability. Phosphorylates SRC; this increases SRC kinase activity. Isoform 2 (FRNK) does not contain a kinase domain and inhibits PTK2/FAK1 phosphorylation and signaling.
6 PublicationsCatalytic activityi
- EC:2.7.10.2PROSITE-ProRule annotation
Activity regulationi
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 454 | ATPCurated | 1 | |
Active sitei | 546 | Proton acceptorPROSITE-ProRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 428 – 434 | ATPCurated | 7 | |
Nucleotide bindingi | 500 – 502 | ATPCurated | 3 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- calcium-dependent cysteine-type endopeptidase activity Source: AgBase
- identical protein binding Source: IntAct
- integrin binding Source: AgBase
- non-membrane spanning protein tyrosine kinase activity Source: GO_Central
- protease binding Source: AgBase
- protein serine/threonine/tyrosine kinase activity Source: RHEA
- protein tyrosine kinase activity Source: AgBase
- signaling receptor binding Source: GO_Central
GO - Biological processi
- actin filament organization Source: AgBase
- angiogenesis Source: GO_Central
- angiogenesis involved in wound healing Source: AgBase
- cell differentiation Source: GO_Central
- epidermal growth factor receptor signaling pathway Source: GO_Central
- innate immune response Source: GO_Central
- negative regulation of anoikis Source: AgBase
- negative regulation of cell-substrate adhesion Source: AgBase
- negative regulation of protein autophosphorylation Source: AgBase
- positive regulation of cell migration Source: GO_Central
- positive regulation of cell population proliferation Source: AgBase
- positive regulation of focal adhesion assembly Source: AgBase
- positive regulation of protein binding Source: AgBase
- positive regulation of protein tyrosine kinase activity Source: AgBase
- positive regulation of substrate-dependent cell migration, cell attachment to substrate Source: AgBase
- protein autophosphorylation Source: AgBase
- protein phosphorylation Source: GO_Central
- radial glia-guided pyramidal neuron migration Source: GO_Central
- regulation of cell adhesion Source: GO_Central
- response to muscle stretch Source: AgBase
- response to pH Source: AgBase
- signal complex assembly Source: InterPro
- transmembrane receptor protein tyrosine kinase signaling pathway Source: GO_Central
- wound healing, spreading of cells Source: AgBase
Keywordsi
Molecular function | Developmental protein, Kinase, Transferase, Tyrosine-protein kinase |
Biological process | Angiogenesis |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
BRENDAi | 2.7.10.2, 1306 |
Reactomei | R-GGA-111465, Apoptotic cleavage of cellular proteins R-GGA-2029482, Regulation of actin dynamics for phagocytic cup formation R-GGA-354192, Integrin signaling R-GGA-354194, GRB2:SOS provides linkage to MAPK signaling for Integrins R-GGA-372708, p130Cas linkage to MAPK signaling for integrins R-GGA-3928662, EPHB-mediated forward signaling R-GGA-418885, DCC mediated attractive signaling R-GGA-4420097, VEGFA-VEGFR2 Pathway R-GGA-5663213, RHO GTPases Activate WASPs and WAVEs R-GGA-8874081, MET activates PTK2 signaling R-GGA-9009391, Extra-nuclear estrogen signaling |
Names & Taxonomyi
Protein namesi | Recommended name: Focal adhesion kinase 1 (EC:2.7.10.2)Short name: FADK 1 Alternative name(s): Focal adhesion kinase-related nonkinase Short name: FRNK Short name: p41/p43FRNK Protein-tyrosine kinase 2 p125FAK pp125FAK |
Gene namesi | Name:PTK2 Synonyms:FAK, FAK1 |
Organismi | Gallus gallus (Chicken) |
Taxonomic identifieri | 9031 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Archelosauria › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galloanserae › Galliformes › Phasianidae › Phasianinae › Gallus |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Cell membrane 1 Publication; Peripheral membrane protein 1 Publication; Cytoplasmic side 1 Publication
Cytoskeleton
- cytoskeleton By similarity
- centrosome By similarity
- cilium basal body By similarity
Nucleus
- Nucleus 1 Publication
Other locations
- focal adhesion 1 Publication
- perinuclear region 1 Publication
Note: Constituent of focal adhesions. Detected at microtubules (By similarity).By similarity
Cytoskeleton
- ciliary basal body Source: UniProtKB
Nucleus
- nucleus Source: UniProtKB-SubCell
Plasma Membrane
- extrinsic component of cytoplasmic side of plasma membrane Source: GO_Central
- sarcolemma Source: AgBase
Other locations
- cytoplasm Source: AgBase
- dendritic spine Source: GO_Central
- focal adhesion Source: AgBase
- perinuclear region of cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane, NucleusPathology & Biotechi
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 395 | D → A: Abolishes interaction with PIK3R1. 1 Publication | 1 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000088076 | 1 – 1053 | Focal adhesion kinase 1Add BLAST | 1053 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 397 | Phosphotyrosine; by autocatalysis1 Publication | 1 | |
Modified residuei | 407 | PhosphotyrosineBy similarity | 1 | |
Modified residuei | 576 | Phosphotyrosine; by SRC2 Publications | 1 | |
Modified residuei | 577 | Phosphotyrosine; by SRCBy similarity | 1 | |
Modified residuei | 863 | Phosphotyrosine1 Publication | 1 | |
Modified residuei | 911 | Phosphoserine1 Publication | 1 | |
Modified residuei | 926 | PhosphotyrosineBy similarity | 1 |
Post-translational modificationi
Keywords - PTMi
PhosphoproteinProteomic databases
PaxDbi | Q00944 |
PRIDEi | Q00944 |
PTM databases
iPTMneti | Q00944 |
Expressioni
Gene expression databases
Bgeei | ENSGALG00000016171, Expressed in colon and 13 other tissues |
ExpressionAtlasi | Q00944, baseline and differential |
Interactioni
Subunit structurei
Interacts with ARHGAP26, GRB7, DCC, PIK3R1, PXN and SRC.
Interacts with the ARP2/3 complex.
8 PublicationsBinary interactionsi
Q00944
GO - Molecular functioni
- identical protein binding Source: IntAct
- integrin binding Source: AgBase
- protease binding Source: AgBase
- signaling receptor binding Source: GO_Central
Protein-protein interaction databases
BioGRIDi | 676665, 2 interactors |
ELMi | Q00944 |
IntActi | Q00944, 11 interactors |
STRINGi | 9031.ENSGALP00000026014 |
Structurei
Secondary structure
3D structure databases
AlphaFoldDBi | Q00944 |
BMRBi | Q00944 |
SMRi | Q00944 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q00944 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 35 – 355 | FERMPROSITE-ProRule annotationAdd BLAST | 321 | |
Domaini | 422 – 680 | Protein kinasePROSITE-ProRule annotationAdd BLAST | 259 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 27 | DisorderedSequence analysisAdd BLAST | 27 | |
Regioni | 686 – 741 | DisorderedSequence analysisAdd BLAST | 56 | |
Regioni | 843 – 892 | DisorderedSequence analysisAdd BLAST | 50 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 9 – 23 | Polar residuesSequence analysisAdd BLAST | 15 | |
Compositional biasi | 727 – 741 | Polar residuesSequence analysisAdd BLAST | 15 |
Domaini
Sequence similaritiesi
Phylogenomic databases
eggNOGi | KOG4257, Eukaryota |
GeneTreei | ENSGT00940000155113 |
HOGENOMi | CLU_002646_0_0_1 |
InParanoidi | Q00944 |
OMAi | ELECMFK |
OrthoDBi | 43729at2759 |
PhylomeDBi | Q00944 |
Family and domain databases
CDDi | cd14473, FERM_B-lobe, 1 hit cd13190, FERM_C_FAK1, 1 hit |
DisProti | DP02120 |
Gene3Di | 1.20.80.10, 1 hit 2.30.29.30, 1 hit |
InterProi | View protein in InterPro IPR019749, Band_41_domain IPR041390, FADK_N IPR041784, FAK1/PYK2_FERM_C IPR014352, FERM/acyl-CoA-bd_prot_sf IPR035963, FERM_2 IPR019748, FERM_central IPR000299, FERM_domain IPR036137, Focal_adhe_kin_target_dom_sf IPR005189, Focal_adhesion_kin_target_dom IPR011009, Kinase-like_dom_sf IPR011993, PH-like_dom_sf IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR001245, Ser-Thr/Tyr_kinase_cat_dom IPR008266, Tyr_kinase_AS IPR020635, Tyr_kinase_cat_dom IPR029071, Ubiquitin-like_domsf |
Pfami | View protein in Pfam PF00373, FERM_M, 1 hit PF18038, FERM_N_2, 1 hit PF03623, Focal_AT, 1 hit PF07714, PK_Tyr_Ser-Thr, 1 hit |
PRINTSi | PR00109, TYRKINASE |
SMARTi | View protein in SMART SM00295, B41, 1 hit SM00219, TyrKc, 1 hit |
SUPFAMi | SSF47031, SSF47031, 1 hit SSF54236, SSF54236, 1 hit SSF56112, SSF56112, 1 hit SSF68993, SSF68993, 1 hit |
PROSITEi | View protein in PROSITE PS00661, FERM_2, 1 hit PS50057, FERM_3, 1 hit PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00109, PROTEIN_KINASE_TYR, 1 hit |
s (2+)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative promoter usage. AlignAdd to basketThis entry has 2 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MAAAYLDPNL NHTPSSSAKT HLGTGMERSP GAMERVLKVF HYFENSSEPT
60 70 80 90 100
TWASIIRHGD ATDVRGIIQK IVDCHKVKNV ACYGLRLSHL QSEEVHWLHL
110 120 130 140 150
DMGVSNVREK FELAHPPEEW KYELRIRYLP KGFLNQFTED KPTLNFFYQQ
160 170 180 190 200
VKNDYMLEIA DQVDQEIALK LGCLEIRRSY GEMRGNALEK KSNYEVLEKD
210 220 230 240 250
VGLRRFFPKS LLDSVKAKTL RKLIQQTFRQ FANLNREESI LKFFEILSPV
260 270 280 290 300
YRFDKECFKC ALGSSWIISV ELAIGPEEGI SYLTDKGANP THLADFNQVQ
310 320 330 340 350
TIQYSNSEDK DRKGMLQLKI AGAPEPLTVT APSLTIAENM ADLIDGYCRL
360 370 380 390 400
VNGATQSFII RPQKEGERAL PSIPKLANNE KQGVRSHTVS VSETDDYAEI
410 420 430 440 450
IDEEDTYTMP STRDYEIQRE RIELGRCIGE GQFGDVHQGI YMSPENPAMA
460 470 480 490 500
VAIKTCKNCT SDSVREKFLQ EALTMRQFDH PHIVKLIGVI TENPVWIIME
510 520 530 540 550
LCTLGELRSF LQVRKFSLDL ASLILYAYQL STALAYLESK RFVHRDIAAR
560 570 580 590 600
NVLVSATDCV KLGDFGLSRY MEDSTYYKAS KGKLPIKWMA PESINFRRFT
610 620 630 640 650
SASDVWMFGV CMWEILMHGV KPFQGVKNND VIGRIENGER LPMPPNCPPT
660 670 680 690 700
LYSLMTKCWA YDPSRRPRFT ELKAQLSTIL EEEKLQQEER MRMESRRQVT
710 720 730 740 750
VSWDSGGSDE APPKPSRPGY PSPRSSEGFY PSPQHMVQPN HYQVSGYSGS
760 770 780 790 800
HGIPAMAGSI YPGQASLLDQ TDSWNHRPQE VSAWQPNMED SGTLDVRGMG
810 820 830 840 850
QVLPTHLMEE RLIRQQQEME EDQRWLEKEE RFLVMKPDVR LSRGSIERED
860 870 880 890 900
GGLQGPAGNQ HIYQPVGKPD HAAPPKKPPR PGAPHLGSLA SLNSPVDSYN
910 920 930 940 950
EGVKIKPQEI SPPPTANLDR SNDKVYENVT GLVKAVIEMS SKIQPAPPEE
960 970 980 990 1000
YVPMVKEVGL ALRTLLATVD ESLPVLPAST HREIEMAQKL LNSDLAELIN
1010 1020 1030 1040 1050
KMKLAQQYVM TSLQQEYKKQ MLTAAHALAV DAKNLLDVID QARLKMISQS
RPH
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A3Q2U9D2 | A0A3Q2U9D2_CHICK | Non-specific protein-tyrosine kinas... | PTK2 | 1,102 | Annotation score: | ||
A0A1D5NY34 | A0A1D5NY34_CHICK | Non-specific protein-tyrosine kinas... | PTK2 | 1,085 | Annotation score: | ||
A0A3Q2UBF5 | A0A3Q2UBF5_CHICK | Non-specific protein-tyrosine kinas... | PTK2 | 1,051 | Annotation score: | ||
A0A1L1RJ83 | A0A1L1RJ83_CHICK | Focal adhesion kinase 1 | PTK2 | 359 | Annotation score: |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_042173 | 1 – 692 | Missing in isoform 2. CuratedAdd BLAST | 692 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M86656 mRNA Translation: AAA48765.1 L08402 mRNA Translation: AAA48766.1 |
PIRi | A45388 PC1239 |
RefSeqi | NP_990766.1, NM_205435.1 [Q00944-1] |
Genome annotation databases
Ensembli | ENSGALT00000072414; ENSGALP00000044406; ENSGALG00000031741 [Q00944-1] |
GeneIDi | 396416 |
KEGGi | gga:396416 |
Keywords - Coding sequence diversityi
Alternative promoter usageSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M86656 mRNA Translation: AAA48765.1 L08402 mRNA Translation: AAA48766.1 |
PIRi | A45388 PC1239 |
RefSeqi | NP_990766.1, NM_205435.1 [Q00944-1] |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1KTM | NMR | - | A | 916-1053 | [»] | |
1PV3 | NMR | - | A | 920-1053 | [»] | |
1QVX | NMR | - | A | 920-1053 | [»] | |
2AEH | X-ray | 2.53 | A/B | 31-399 | [»] | |
2AL6 | X-ray | 2.35 | A/B | 31-405 | [»] | |
2J0J | X-ray | 2.80 | A | 31-686 | [»] | |
2J0K | X-ray | 3.00 | A/B | 31-686 | [»] | |
2J0L | X-ray | 2.30 | A | 411-686 | [»] | |
2J0M | X-ray | 2.80 | A | 31-399 | [»] | |
B | 411-686 | [»] | ||||
2JKK | X-ray | 2.00 | A | 411-686 | [»] | |
2JKM | X-ray | 2.31 | A | 411-686 | [»] | |
2JKO | X-ray | 1.65 | A | 411-686 | [»] | |
2JKQ | X-ray | 2.60 | A | 411-686 | [»] | |
2L6F | NMR | - | A | 916-1053 | [»] | |
2L6G | NMR | - | A | 916-1053 | [»] | |
2L6H | NMR | - | A | 916-1053 | [»] | |
3ZDT | X-ray | 3.15 | A/B | 31-405 | [»] | |
4BRX | X-ray | 2.05 | A | 411-686 | [»] | |
4C7T | X-ray | 2.05 | A | 411-686 | [»] | |
4CYE | X-ray | 3.20 | A/B | 31-405 | [»] | |
4D4R | X-ray | 1.55 | A/B | 411-686 | [»] | |
4D4S | X-ray | 2.00 | A/B | 411-686 | [»] | |
4D4V | X-ray | 2.10 | A/B | 411-686 | [»] | |
4D4Y | X-ray | 1.80 | A/B | 411-686 | [»] | |
4D55 | X-ray | 2.30 | A | 411-686 | [»] | |
4D58 | X-ray | 1.95 | A/B | 411-686 | [»] | |
4D5H | X-ray | 1.75 | A/B | 411-686 | [»] | |
4D5K | X-ray | 1.75 | A/B | 411-686 | [»] | |
6CB0 | X-ray | 1.97 | A/B | 31-405 | [»] | |
6GCR | X-ray | 2.30 | A | 411-686 | [»] | |
6GCW | X-ray | 2.00 | A/B | 411-686 | [»] | |
6GCX | X-ray | 1.55 | A | 411-686 | [»] | |
6TY3 | electron microscopy | 6.32 | A/B | 30-686 | [»] | |
6TY4 | electron microscopy | 5.96 | A/B | 30-686 | [»] | |
AlphaFoldDBi | Q00944 | |||||
BMRBi | Q00944 | |||||
SMRi | Q00944 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 676665, 2 interactors |
ELMi | Q00944 |
IntActi | Q00944, 11 interactors |
STRINGi | 9031.ENSGALP00000026014 |
PTM databases
iPTMneti | Q00944 |
Proteomic databases
PaxDbi | Q00944 |
PRIDEi | Q00944 |
Genome annotation databases
Ensembli | ENSGALT00000072414; ENSGALP00000044406; ENSGALG00000031741 [Q00944-1] |
GeneIDi | 396416 |
KEGGi | gga:396416 |
Organism-specific databases
CTDi | 5747 |
Phylogenomic databases
eggNOGi | KOG4257, Eukaryota |
GeneTreei | ENSGT00940000155113 |
HOGENOMi | CLU_002646_0_0_1 |
InParanoidi | Q00944 |
OMAi | ELECMFK |
OrthoDBi | 43729at2759 |
PhylomeDBi | Q00944 |
Enzyme and pathway databases
BRENDAi | 2.7.10.2, 1306 |
Reactomei | R-GGA-111465, Apoptotic cleavage of cellular proteins R-GGA-2029482, Regulation of actin dynamics for phagocytic cup formation R-GGA-354192, Integrin signaling R-GGA-354194, GRB2:SOS provides linkage to MAPK signaling for Integrins R-GGA-372708, p130Cas linkage to MAPK signaling for integrins R-GGA-3928662, EPHB-mediated forward signaling R-GGA-418885, DCC mediated attractive signaling R-GGA-4420097, VEGFA-VEGFR2 Pathway R-GGA-5663213, RHO GTPases Activate WASPs and WAVEs R-GGA-8874081, MET activates PTK2 signaling R-GGA-9009391, Extra-nuclear estrogen signaling |
Miscellaneous databases
EvolutionaryTracei | Q00944 |
PROi | PR:Q00944 |
Gene expression databases
Bgeei | ENSGALG00000016171, Expressed in colon and 13 other tissues |
ExpressionAtlasi | Q00944, baseline and differential |
Family and domain databases
CDDi | cd14473, FERM_B-lobe, 1 hit cd13190, FERM_C_FAK1, 1 hit |
DisProti | DP02120 |
Gene3Di | 1.20.80.10, 1 hit 2.30.29.30, 1 hit |
InterProi | View protein in InterPro IPR019749, Band_41_domain IPR041390, FADK_N IPR041784, FAK1/PYK2_FERM_C IPR014352, FERM/acyl-CoA-bd_prot_sf IPR035963, FERM_2 IPR019748, FERM_central IPR000299, FERM_domain IPR036137, Focal_adhe_kin_target_dom_sf IPR005189, Focal_adhesion_kin_target_dom IPR011009, Kinase-like_dom_sf IPR011993, PH-like_dom_sf IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR001245, Ser-Thr/Tyr_kinase_cat_dom IPR008266, Tyr_kinase_AS IPR020635, Tyr_kinase_cat_dom IPR029071, Ubiquitin-like_domsf |
Pfami | View protein in Pfam PF00373, FERM_M, 1 hit PF18038, FERM_N_2, 1 hit PF03623, Focal_AT, 1 hit PF07714, PK_Tyr_Ser-Thr, 1 hit |
PRINTSi | PR00109, TYRKINASE |
SMARTi | View protein in SMART SM00295, B41, 1 hit SM00219, TyrKc, 1 hit |
SUPFAMi | SSF47031, SSF47031, 1 hit SSF54236, SSF54236, 1 hit SSF56112, SSF56112, 1 hit SSF68993, SSF68993, 1 hit |
PROSITEi | View protein in PROSITE PS00661, FERM_2, 1 hit PS50057, FERM_3, 1 hit PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00109, PROTEIN_KINASE_TYR, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | FAK1_CHICK | |
Accessioni | Q00944Primary (citable) accession number: Q00944 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 1, 1993 |
Last sequence update: | February 1, 1994 | |
Last modified: | May 25, 2022 | |
This is version 202 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families