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Entry version 105 (08 May 2019)
Sequence version 2 (20 May 2008)
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Protein

Epithelial cell-transforming sequence 2 oncogene-like

Gene

ECT2L

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May act as a guanine nucleotide exchange factor (GEF).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGuanine-nucleotide releasing factor

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Epithelial cell-transforming sequence 2 oncogene-like
Alternative name(s):
Lung-specific F-box and DH domain-containing protein
Putative guanine nucleotide exchange factor LFDH
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ECT2L
Synonyms:C6orf91, LFDH
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:21118 ECT2L

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q008S8

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
345930

Open Targets

More...
OpenTargetsi
ENSG00000203734

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134893289

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ECT2L

Domain mapping of disease mutations (DMDM)

More...
DMDMi
189046616

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003360751 – 904Epithelial cell-transforming sequence 2 oncogene-likeAdd BLAST904

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q008S8

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q008S8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q008S8

PeptideAtlas

More...
PeptideAtlasi
Q008S8

PRoteomics IDEntifications database

More...
PRIDEi
Q008S8

ProteomicsDB human proteome resource

More...
ProteomicsDBi
57884

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q008S8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q008S8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000203734 Expressed in 72 organ(s), highest expression level in right uterine tube

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q008S8 baseline and differential

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA035488

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
131369, 3 interactors

Protein interaction database and analysis system

More...
IntActi
Q008S8, 3 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000442307

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q008S8

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini75 – 121F-boxAdd BLAST47
Domaini566 – 754DHPROSITE-ProRule annotationAdd BLAST189

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IRSS Eukaryota
ENOG4110R79 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158839

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000067954

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q008S8

Identification of Orthologs from Complete Genome Data

More...
OMAi
CDEEISF

Database of Orthologous Groups

More...
OrthoDBi
1047475at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q008S8

TreeFam database of animal gene trees

More...
TreeFami
TF343796

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00160 RhoGEF, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.900.10, 1 hit
2.30.29.30, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR035899 DBL_dom_sf
IPR000219 DH-domain
IPR025592 DUF4347
IPR036047 F-box-like_dom_sf
IPR001810 F-box_dom
IPR011993 PH-like_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14252 DUF4347, 1 hit
PF12937 F-box-like, 1 hit
PF00621 RhoGEF, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00325 RhoGEF, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48065 SSF48065, 1 hit
SSF81383 SSF81383, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50010 DH_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q008S8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MESFHTRFSA WTPFSNKSLN RQLFQERVAL ISHWFDLWTN KQRQEFLFAI
60 70 80 90 100
FLRCTKSQLR FVQDWFSERM QVAKVDFSTV LPRFISLYIF SFLSPKDLCA
110 120 130 140 150
AAQVSWPWKF LTEQDCLWMP KCVKFGWFLP YTPTDNEYGA WKRHYIACVS
160 170 180 190 200
HLDWLTPREA AATYGTLNEP KTEDEELLER QREKCLRKRI WEKIALRKKE
210 220 230 240 250
LFKVRPPWVS GTCCSSVLKP RCQPRLSQTV RERVGLHEAL EKQLVLTSLE
260 270 280 290 300
TLPKRSNISG SHSYPLLSKK NWHGVHKNDD RSSYALRPHF MLISSRIPAY
310 320 330 340 350
EMVMESVKAG VVSVVYEHSV TLESLLYLIE KALDGQKAQS IGIFSDGDSR
360 370 380 390 400
EINLLQGYKI GVKNLLRPEV RDFWEKLGSY VATEEEGGHV DFFVPLGASE
410 420 430 440 450
AGIEVLSQLS QLTGTFFTAP TGIATGSYQH ILSDWLGSQW GKAPSSIYFC
460 470 480 490 500
ESKLQTWSSF TDFLEETLKT VRKQLYPFFK ELQKSISGRM IGQFMFDTMG
510 520 530 540 550
MTNILNNQDT AQALADGLME LSKEDSERNV VEDNSWDTKS RLSKNDLNFE
560 570 580 590 600
ALINLERILQ KDSAEKRARV VRELLQSERK YVQILEIVRD VYVAPLKAAL
610 620 630 640 650
SSNRAILSAA NIQIIFCDIL QILSLNRQFL DNLRDRLQEW GPAHCVGEIV
660 670 680 690 700
TKFGSQLNTY TNFFNNYPVI LKTIEKCREM IPAFRTFLKR HDKTIVTKML
710 720 730 740 750
SLPELLLYPS RRFEEYLNLL YAVRLHTPAE HVDRGDLTTA IDQIKKYKGY
760 770 780 790 800
IDQMKQNITM KDHLSDIQRI IWGCPTLSEV NRYLIRVQDV AQLHCCDEEI
810 820 830 840 850
SFSLRLYEHI HDLSLFLFND ALLVSSRGTS HTPFERTSKT TYQFIASVAL
860 870 880 890 900
HRLLIENIPD SKYVKNAFIL QGPKYKWICA TEIEDDKFLW LSVLRNAIKS

SMEK
Length:904
Mass (Da):104,880
Last modified:May 20, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCF4AD8C84D94E983
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B7ZBI6B7ZBI6_HUMAN
Epithelial cell-transforming sequen...
ECT2L
77Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence ABI98401 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti60R → S in ABI98401 (Ref. 3) Curated1
Sequence conflicti64D → E in ABI98401 (Ref. 3) Curated1
Sequence conflicti472R → K in ABI98401 (Ref. 3) Curated1
Sequence conflicti641G → D in ABI98401 (Ref. 3) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_051984483Q → H. Corresponds to variant dbSNP:rs12198781Ensembl.1
Natural variantiVAR_043482527E → K. Corresponds to variant dbSNP:rs1529151EnsemblClinVar.1
Natural variantiVAR_043483594A → T. Corresponds to variant dbSNP:rs11968285EnsemblClinVar.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL121834 Genomic DNA No translation available.
BC146884 mRNA Translation: AAI46885.1
DQ904331 mRNA Translation: ABI98401.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS43508.1

NCBI Reference Sequences

More...
RefSeqi
NP_001071174.1, NM_001077706.2
NP_001181966.1, NM_001195037.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000367682; ENSP00000356655; ENSG00000203734
ENST00000423192; ENSP00000387388; ENSG00000203734
ENST00000541398; ENSP00000442307; ENSG00000203734

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
345930

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:345930

UCSC genome browser

More...
UCSCi
uc003qif.2 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL121834 Genomic DNA No translation available.
BC146884 mRNA Translation: AAI46885.1
DQ904331 mRNA Translation: ABI98401.1 Different initiation.
CCDSiCCDS43508.1
RefSeqiNP_001071174.1, NM_001077706.2
NP_001181966.1, NM_001195037.2

3D structure databases

SMRiQ008S8
ModBaseiSearch...

Protein-protein interaction databases

BioGridi131369, 3 interactors
IntActiQ008S8, 3 interactors
STRINGi9606.ENSP00000442307

PTM databases

iPTMnetiQ008S8
PhosphoSitePlusiQ008S8

Polymorphism and mutation databases

BioMutaiECT2L
DMDMi189046616

Proteomic databases

EPDiQ008S8
jPOSTiQ008S8
PaxDbiQ008S8
PeptideAtlasiQ008S8
PRIDEiQ008S8
ProteomicsDBi57884

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000367682; ENSP00000356655; ENSG00000203734
ENST00000423192; ENSP00000387388; ENSG00000203734
ENST00000541398; ENSP00000442307; ENSG00000203734
GeneIDi345930
KEGGihsa:345930
UCSCiuc003qif.2 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
345930
DisGeNETi345930

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ECT2L
HGNCiHGNC:21118 ECT2L
HPAiHPA035488
neXtProtiNX_Q008S8
OpenTargetsiENSG00000203734
PharmGKBiPA134893289

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IRSS Eukaryota
ENOG4110R79 LUCA
GeneTreeiENSGT00940000158839
HOGENOMiHOG000067954
InParanoidiQ008S8
OMAiCDEEISF
OrthoDBi1047475at2759
PhylomeDBiQ008S8
TreeFamiTF343796

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ECT2L human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
ECT2L

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
345930

Protein Ontology

More...
PROi
PR:Q008S8

Gene expression databases

BgeeiENSG00000203734 Expressed in 72 organ(s), highest expression level in right uterine tube
ExpressionAtlasiQ008S8 baseline and differential

Family and domain databases

CDDicd00160 RhoGEF, 1 hit
Gene3Di1.20.900.10, 1 hit
2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR035899 DBL_dom_sf
IPR000219 DH-domain
IPR025592 DUF4347
IPR036047 F-box-like_dom_sf
IPR001810 F-box_dom
IPR011993 PH-like_dom_sf
PfamiView protein in Pfam
PF14252 DUF4347, 1 hit
PF12937 F-box-like, 1 hit
PF00621 RhoGEF, 1 hit
SMARTiView protein in SMART
SM00325 RhoGEF, 1 hit
SUPFAMiSSF48065 SSF48065, 1 hit
SSF81383 SSF81383, 1 hit
PROSITEiView protein in PROSITE
PS50010 DH_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiECT2L_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q008S8
Secondary accession number(s): B2RUV6
, Q5JWK2, Q5JWK3, Q5JWK4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 20, 2008
Last modified: May 8, 2019
This is version 105 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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