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Entry version 112 (02 Jun 2021)
Sequence version 1 (14 Nov 2006)
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Protein

ADP-ribosylation factor 6

Gene

ARF6

Organism
Sus scrofa (Pig)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton remodeling (By similarity).

Required for normal completion of mitotic cytokinesis (By similarity).

Plays a role in the reorganization of the actin cytoskeleton and the formation of stress fibers (By similarity).

Involved in the regulation of dendritic spine development, contributing to the regulation of dendritic branching and filopodia extension (By similarity).

Plays an important role in membrane trafficking, during junctional remodeling and epithelial polarization. Regulates surface levels of adherens junction proteins such as CDH1 (By similarity).

Required for NTRK1 sorting to the recycling pathway from early endosomes (By similarity).

By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

Activation is generally mediated by a guanine exchange factor (GEF), while inactivation through hydrolysis of bound GTP is catalyzed by a GTPase activating protein (GAP). Activated by ASAP3. Inactivated by ACAP1 and ACAP2 (By similarity). Activated by NGF via NTRK1 (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi20 – 27GTPBy similarity8
Nucleotide bindingi63 – 67GTPBy similarity5
Nucleotide bindingi122 – 125GTPBy similarity4

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processDifferentiation, Neurogenesis, Protein transport, Transport
LigandGTP-binding, Nucleotide-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-SSC-8854214, TBC/RABGAPs
R-SSC-8875656, MET receptor recycling

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ADP-ribosylation factor 6
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ARF6
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSus scrofa (Pig)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9823 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaArtiodactylaSuinaSuidaeSus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000314985 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1
  • UP000008227 Componenti: Chromosome 1

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...
VGNCi
VGNC:85448, ARF6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cell membrane, Cell projection, Cytoplasm, Endosome, Golgi apparatus, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedBy similarity
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002896592 – 175ADP-ribosylation factor 6Add BLAST174

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position(s) and the type of covalently attached lipid group(s).<p><a href='/help/lipid' target='_top'>More...</a></p>Lipidationi2N-myristoyl glycineBy similarity1

Keywords - PTMi

Lipoprotein, Myristate

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q007T5

PeptideAtlas

More...
PeptideAtlasi
Q007T5

PRoteomics IDEntifications database

More...
PRIDEi
Q007T5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSSSCG00000005012, Expressed in spleen and 47 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q007T5, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q007T5, SS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts (when activated) with GGA1, GGA2 and GGA3; the interaction is required for proper subcellular location of GGA1, GGA2 and GGA3 (By similarity).

Interacts with PIP5K1C.

Interacts with USP6 (via Rab-GAP TBC domain).

Interacts with RAB11FIP3 and RAB11FIP4.

Interacts with HERC1.

Interacts with ARHGAP21.

Interacts with ASAP3; the interaction is stabilized by calcium ions.

Interacts with NCS1/FREQ at the plasma membrane.

Interacts with TBC1D24.

Interacts with ECPAS.

Interacts with MICALL1.

Interacts with SPAG9 homodimers, forming heterotetramers.

Interacts with CYTH3 (By similarity).

Interacts with ASAP2 (By similarity).

Interacts with UACA (By similarity).

Interacts with KIF23, forming heterodimers and heterotetramers (By similarity).

Interacts with C9orf72 (By similarity).

Interacts (GTP-bound form) with TJAP1/PILT (By similarity).

By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9823.ENSSSCP00000005391

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q007T5

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the small GTPase superfamily. Arf family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0071, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156593

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_040729_9_4_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q007T5

Identification of Orthologs from Complete Genome Data

More...
OMAi
IQDREMK

Database of Orthologous Groups

More...
OrthoDBi
1362554at2759

TreeFam database of animal gene trees

More...
TreeFami
TF300808

Family and domain databases

Conserved Domains Database

More...
CDDi
cd04149, Arf6, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR041838, Arf6
IPR027417, P-loop_NTPase
IPR005225, Small_GTP-bd_dom
IPR006689, Small_GTPase_ARF/SAR

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00025, Arf, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00328, SAR1GTPBP

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00231, small_GTP, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51417, ARF, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q007T5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGKVLSKIFG NKEMRILMLG LDAAGKTTIL YKLKLGQSVT TIPTVGFNVE
60 70 80 90 100
TVTYKNVKFN VWDVGGQDKI RPLWRHYYTG TQGLIFVVDC ADRDRIDEAR
110 120 130 140 150
QELHRIINDR EMRDAIILIF ANKQDLPDAM KPHEIQEKLG LTRIRDRNWY
160 170
VQPSCATSGD GLYEGLTWLT SNYKS
Length:175
Mass (Da):20,082
Last modified:November 14, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i49E38E59AEA52B98
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DQ915493 mRNA Translation: ABJ09398.1

NCBI Reference Sequences

More...
RefSeqi
NP_001072145.1, NM_001078677.1
XP_005659996.1, XM_005659939.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSSSCT00000005528; ENSSSCP00000005391; ENSSSCG00000005012
ENSSSCT00000058177; ENSSSCP00000058854; ENSSSCG00000005012
ENSSSCT00000074052; ENSSSCP00000064421; ENSSSCG00000005012
ENSSSCT00005032868; ENSSSCP00005020040; ENSSSCG00005020845
ENSSSCT00005032906; ENSSSCP00005020061; ENSSSCG00005020845
ENSSSCT00015036207; ENSSSCP00015014421; ENSSSCG00015027240
ENSSSCT00015036246; ENSSSCP00015014438; ENSSSCG00015027240
ENSSSCT00015036282; ENSSSCP00015014456; ENSSSCG00015027240
ENSSSCT00025105859; ENSSSCP00025047388; ENSSSCG00025076444
ENSSSCT00025105874; ENSSSCP00025047400; ENSSSCG00025076444
ENSSSCT00025105884; ENSSSCP00025047408; ENSSSCG00025076444
ENSSSCT00030094340; ENSSSCP00030043491; ENSSSCG00030067449
ENSSSCT00030094368; ENSSSCP00030043503; ENSSSCG00030067449
ENSSSCT00030094386; ENSSSCP00030043509; ENSSSCG00030067449
ENSSSCT00035025265; ENSSSCP00035009549; ENSSSCG00035019495
ENSSSCT00035025273; ENSSSCP00035009551; ENSSSCG00035019495
ENSSSCT00035025274; ENSSSCP00035009552; ENSSSCG00035019495
ENSSSCT00040084027; ENSSSCP00040036622; ENSSSCG00040061728
ENSSSCT00040084060; ENSSSCP00040036638; ENSSSCG00040061728
ENSSSCT00040084096; ENSSSCP00040036659; ENSSSCG00040061728
ENSSSCT00045014781; ENSSSCP00045010256; ENSSSCG00045008747
ENSSSCT00045014803; ENSSSCP00045010272; ENSSSCG00045008747
ENSSSCT00045014827; ENSSSCP00045010290; ENSSSCG00045008747
ENSSSCT00050098190; ENSSSCP00050042385; ENSSSCG00050071942
ENSSSCT00050098196; ENSSSCP00050042389; ENSSSCG00050071942
ENSSSCT00050098202; ENSSSCP00050042391; ENSSSCG00050071942
ENSSSCT00055021488; ENSSSCP00055017025; ENSSSCG00055010938
ENSSSCT00055021515; ENSSSCP00055017047; ENSSSCG00055010938
ENSSSCT00055021529; ENSSSCP00055017057; ENSSSCG00055010938
ENSSSCT00060010997; ENSSSCP00060004061; ENSSSCG00060008590
ENSSSCT00060011000; ENSSSCP00060004063; ENSSSCG00060008590
ENSSSCT00060011003; ENSSSCP00060004065; ENSSSCG00060008590
ENSSSCT00065083268; ENSSSCP00065036298; ENSSSCG00065060772
ENSSSCT00065083279; ENSSSCP00065036304; ENSSSCG00065060772
ENSSSCT00065083291; ENSSSCP00065036311; ENSSSCG00065060772
ENSSSCT00070001826; ENSSSCP00070001520; ENSSSCG00070000951
ENSSSCT00070001832; ENSSSCP00070001526; ENSSSCG00070000951
ENSSSCT00070001838; ENSSSCP00070001532; ENSSSCG00070000951

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
780425

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ssc:780425

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ915493 mRNA Translation: ABJ09398.1
RefSeqiNP_001072145.1, NM_001078677.1
XP_005659996.1, XM_005659939.2

3D structure databases

SMRiQ007T5
ModBaseiSearch...

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000005391

Proteomic databases

PaxDbiQ007T5
PeptideAtlasiQ007T5
PRIDEiQ007T5

Genome annotation databases

EnsembliENSSSCT00000005528; ENSSSCP00000005391; ENSSSCG00000005012
ENSSSCT00000058177; ENSSSCP00000058854; ENSSSCG00000005012
ENSSSCT00000074052; ENSSSCP00000064421; ENSSSCG00000005012
ENSSSCT00005032868; ENSSSCP00005020040; ENSSSCG00005020845
ENSSSCT00005032906; ENSSSCP00005020061; ENSSSCG00005020845
ENSSSCT00015036207; ENSSSCP00015014421; ENSSSCG00015027240
ENSSSCT00015036246; ENSSSCP00015014438; ENSSSCG00015027240
ENSSSCT00015036282; ENSSSCP00015014456; ENSSSCG00015027240
ENSSSCT00025105859; ENSSSCP00025047388; ENSSSCG00025076444
ENSSSCT00025105874; ENSSSCP00025047400; ENSSSCG00025076444
ENSSSCT00025105884; ENSSSCP00025047408; ENSSSCG00025076444
ENSSSCT00030094340; ENSSSCP00030043491; ENSSSCG00030067449
ENSSSCT00030094368; ENSSSCP00030043503; ENSSSCG00030067449
ENSSSCT00030094386; ENSSSCP00030043509; ENSSSCG00030067449
ENSSSCT00035025265; ENSSSCP00035009549; ENSSSCG00035019495
ENSSSCT00035025273; ENSSSCP00035009551; ENSSSCG00035019495
ENSSSCT00035025274; ENSSSCP00035009552; ENSSSCG00035019495
ENSSSCT00040084027; ENSSSCP00040036622; ENSSSCG00040061728
ENSSSCT00040084060; ENSSSCP00040036638; ENSSSCG00040061728
ENSSSCT00040084096; ENSSSCP00040036659; ENSSSCG00040061728
ENSSSCT00045014781; ENSSSCP00045010256; ENSSSCG00045008747
ENSSSCT00045014803; ENSSSCP00045010272; ENSSSCG00045008747
ENSSSCT00045014827; ENSSSCP00045010290; ENSSSCG00045008747
ENSSSCT00050098190; ENSSSCP00050042385; ENSSSCG00050071942
ENSSSCT00050098196; ENSSSCP00050042389; ENSSSCG00050071942
ENSSSCT00050098202; ENSSSCP00050042391; ENSSSCG00050071942
ENSSSCT00055021488; ENSSSCP00055017025; ENSSSCG00055010938
ENSSSCT00055021515; ENSSSCP00055017047; ENSSSCG00055010938
ENSSSCT00055021529; ENSSSCP00055017057; ENSSSCG00055010938
ENSSSCT00060010997; ENSSSCP00060004061; ENSSSCG00060008590
ENSSSCT00060011000; ENSSSCP00060004063; ENSSSCG00060008590
ENSSSCT00060011003; ENSSSCP00060004065; ENSSSCG00060008590
ENSSSCT00065083268; ENSSSCP00065036298; ENSSSCG00065060772
ENSSSCT00065083279; ENSSSCP00065036304; ENSSSCG00065060772
ENSSSCT00065083291; ENSSSCP00065036311; ENSSSCG00065060772
ENSSSCT00070001826; ENSSSCP00070001520; ENSSSCG00070000951
ENSSSCT00070001832; ENSSSCP00070001526; ENSSSCG00070000951
ENSSSCT00070001838; ENSSSCP00070001532; ENSSSCG00070000951
GeneIDi780425
KEGGissc:780425

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
382
VGNCiVGNC:85448, ARF6

Phylogenomic databases

eggNOGiKOG0071, Eukaryota
GeneTreeiENSGT00940000156593
HOGENOMiCLU_040729_9_4_1
InParanoidiQ007T5
OMAiIQDREMK
OrthoDBi1362554at2759
TreeFamiTF300808

Enzyme and pathway databases

ReactomeiR-SSC-8854214, TBC/RABGAPs
R-SSC-8875656, MET receptor recycling

Gene expression databases

BgeeiENSSSCG00000005012, Expressed in spleen and 47 other tissues
ExpressionAtlasiQ007T5, baseline and differential
GenevisibleiQ007T5, SS

Family and domain databases

CDDicd04149, Arf6, 1 hit
InterProiView protein in InterPro
IPR041838, Arf6
IPR027417, P-loop_NTPase
IPR005225, Small_GTP-bd_dom
IPR006689, Small_GTPase_ARF/SAR
PfamiView protein in Pfam
PF00025, Arf, 1 hit
PRINTSiPR00328, SAR1GTPBP
SUPFAMiSSF52540, SSF52540, 1 hit
TIGRFAMsiTIGR00231, small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51417, ARF, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiARF6_PIG
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q007T5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: November 14, 2006
Last modified: June 2, 2021
This is version 112 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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