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UniProtKB - Q00765 (REEP5_HUMAN)

Entry version 167 (10 Feb 2021)
Sequence version 3 (22 Nov 2005)
Previous versions | rss
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Protein

Receptor expression-enhancing protein 5

Gene

REEP5

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May promote functional cell surface expression of olfactory receptors.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q00765

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-381753, Olfactory Signaling Pathway

SIGNOR Signaling Network Open Resource

More...SIGNORi		Q00765

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Receptor expression-enhancing protein 5
Alternative name(s):
Polyposis locus protein 1
Protein TB2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:REEP5
Synonyms:C5orf18, DP1, TB2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:30077, REEP5

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		125265, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q00765

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000129625.12

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei35 – 55HelicalSequence analysisAdd BLAST21
Transmembranei90 – 110HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		7905

Open Targets

More...OpenTargetsi		ENSG00000129625

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134882361

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q00765, Tbio

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...ChEMBLi		CHEMBL4295797

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		REEP5

Domain mapping of disease mutations (DMDM)

More...DMDMi		82654932

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001018151 – 189Receptor expression-enhancing protein 5Add BLAST189

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q00765

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q00765

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q00765

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q00765

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q00765

PeptideAtlas

More...PeptideAtlasi		Q00765

PRoteomics IDEntifications database

More...PRIDEi		Q00765

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		57872 [Q00765-1]
6755

Consortium for Top Down Proteomics

More...TopDownProteomicsi		Q00765-1 [Q00765-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q00765

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q00765

SwissPalm database of S-palmitoylation events

More...SwissPalmi		Q00765

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in circumvallate papillae and testis.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000129625, Expressed in middle temporal gyrus and 258 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q00765, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q00765, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000129625, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with ATL1 (By similarity).

Interacts with ATL2 (PubMed:19665976).

Interacts with ZFYVE27 (PubMed:23969831).

By similarity2 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		113637, 105 interactors

CORUM comprehensive resource of mammalian protein complexes

More...CORUMi		Q00765

Protein interaction database and analysis system

More...IntActi		Q00765, 90 interactors

Molecular INTeraction database

More...MINTi		Q00765

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000368959

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q00765, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the DP1 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1725, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000157873

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q00765

Identification of Orthologs from Complete Genome Data

More...OMAi		LYYFPWY

Database of Orthologous Groups

More...OrthoDBi		1473891at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q00765

TreeFam database of animal gene trees

More...TreeFami		TF314913

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR004345, TB2_DP1_HVA22

The PANTHER Classification System

More...PANTHERi		PTHR12300, PTHR12300, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF03134, TB2_DP1_HVA22, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q00765-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSAAMRERFD RFLHEKNCMT DLLAKLEAKT GVNRSFIALG VIGLVALYLV 
        60         70         80         90        100
FGYGASLLCN LIGFGYPAYI SIKAIESPNK EDDTQWLTYW VVYGVFSIAE 
       110        120        130        140        150
FFSDIFLSWF PFYYMLKCGF LLWCMAPSPS NGAELLYKRI IRPFFLKHES 
       160        170        180 
QMDSVVKDLK DKAKETADAI TKEAKKATVN LLGEEKKST
Length:189
Mass (Da):21,493
Last modified:November 22, 2005 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF4E57E500CB7C831
GO
Isoform 2 (identifier: Q00765-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     118-189: CGFLLWCMAP...NLLGEEKKST → VWSGLGFLLPRCLL

Show »
Length:131
Mass (Da):14,997
Checksum:iD6B307C92BDA7E0C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E2QRG8E2QRG8_HUMAN
Receptor expression-enhancing prote...
REEP5
165Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B7Z510B7Z510_HUMAN
Receptor expression-enhancing prote...
REEP5
122Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0Y8J8H0Y8J8_HUMAN
Receptor expression-enhancing prote...
REEP5
145Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B7Z332B7Z332_HUMAN
Receptor expression-enhancing prote...
REEP5
99Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAA60136 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAA66351 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAH65926 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti115M → I in AAA66351 (PubMed:1651562).Curated1
Sequence conflicti163A → S in AAA60136 (PubMed:1678319).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_056633118 – 189CGFLL…EKKST → VWSGLGFLLPRCLL in isoform 2. 1 PublicationAdd BLAST72

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
M73547 mRNA Translation: AAA60136.1 Different initiation.
M74090 mRNA Translation: AAA66351.1 Different initiation.
AY562243 mRNA Translation: AAT70688.1
AK299902 mRNA Translation: BAH13167.1
AC008536 Genomic DNA No translation available.
AC008575 Genomic DNA No translation available.
CH471086 Genomic DNA Translation: EAW48994.1
CH471086 Genomic DNA Translation: EAW48995.1
BC000232 mRNA Translation: AAH00232.2
BC065926 mRNA Translation: AAH65926.1 Different initiation.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS4109.2 [Q00765-1]

Protein sequence database of the Protein Information Resource

More...PIRi		A39658

NCBI Reference Sequences

More...RefSeqi		NP_005660.4, NM_005669.4 [Q00765-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000379638; ENSP00000368959; ENSG00000129625 [Q00765-1]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		7905

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:7905

UCSC genome browser

More...UCSCi		uc003kqe.2, human [Q00765-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M73547 mRNA Translation: AAA60136.1 Different initiation.
M74090 mRNA Translation: AAA66351.1 Different initiation.
AY562243 mRNA Translation: AAT70688.1
AK299902 mRNA Translation: BAH13167.1
AC008536 Genomic DNA No translation available.
AC008575 Genomic DNA No translation available.
CH471086 Genomic DNA Translation: EAW48994.1
CH471086 Genomic DNA Translation: EAW48995.1
BC000232 mRNA Translation: AAH00232.2
BC065926 mRNA Translation: AAH65926.1 Different initiation.
CCDSiCCDS4109.2 [Q00765-1]
PIRiA39658
RefSeqiNP_005660.4, NM_005669.4 [Q00765-1]

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi113637, 105 interactors
CORUMiQ00765
IntActiQ00765, 90 interactors
MINTiQ00765
STRINGi9606.ENSP00000368959

Chemistry databases

ChEMBLiCHEMBL4295797

PTM databases

iPTMnetiQ00765
PhosphoSitePlusiQ00765
SwissPalmiQ00765

Genetic variation databases

BioMutaiREEP5
DMDMi82654932

Proteomic databases

EPDiQ00765
jPOSTiQ00765
MassIVEiQ00765
MaxQBiQ00765
PaxDbiQ00765
PeptideAtlasiQ00765
PRIDEiQ00765
ProteomicsDBi57872 [Q00765-1]
6755
TopDownProteomicsiQ00765-1 [Q00765-1]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		25369, 275 antibodies

The DNASU plasmid repository

More...DNASUi		7905

Genome annotation databases

EnsembliENST00000379638; ENSP00000368959; ENSG00000129625 [Q00765-1]
GeneIDi7905
KEGGihsa:7905
UCSCiuc003kqe.2, human [Q00765-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		7905
DisGeNETi7905

GeneCards: human genes, protein and diseases

More...GeneCardsi		REEP5
HGNCiHGNC:30077, REEP5
HPAiENSG00000129625, Low tissue specificity
MIMi125265, gene
neXtProtiNX_Q00765
OpenTargetsiENSG00000129625
PharmGKBiPA134882361
VEuPathDBiHostDB:ENSG00000129625.12

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1725, Eukaryota
GeneTreeiENSGT00940000157873
InParanoidiQ00765
OMAiLYYFPWY
OrthoDBi1473891at2759
PhylomeDBiQ00765
TreeFamiTF314913

Enzyme and pathway databases

PathwayCommonsiQ00765
ReactomeiR-HSA-381753, Olfactory Signaling Pathway
SIGNORiQ00765

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		7905, 9 hits in 874 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		REEP5, human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		REEP5

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		7905
PharosiQ00765, Tbio

Protein Ontology

More...PROi		PR:Q00765
RNActiQ00765, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000129625, Expressed in middle temporal gyrus and 258 other tissues
ExpressionAtlasiQ00765, baseline and differential
GenevisibleiQ00765, HS

Family and domain databases

InterProiView protein in InterPro
IPR004345, TB2_DP1_HVA22
PANTHERiPTHR12300, PTHR12300, 1 hit
PfamiView protein in Pfam
PF03134, TB2_DP1_HVA22, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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MobiDB: a database of protein disorder and mobility annotations

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiREEP5_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q00765
Secondary accession number(s): B7Z681
, D3DT04, Q04198, Q5QGT0, Q9BWH9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 1, 1993
Last sequence update: November 22, 2005
Last modified: February 10, 2021
This is version 167 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
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