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Protein

Lactococcin-A transport/processing ATP-binding protein LcnC

Gene

lcnC

Organism
Lactococcus lactis subsp. lactis (Streptococcus lactis)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in the export process of the bacteriocin lactococcin A.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei17PROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi515 – 522ATPPROSITE-ProRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protease, Thiol protease
Biological processBacteriocin transport, Protein transport, Transport
LigandATP-binding, Nucleotide-binding

Protein family/group databases

MEROPSiC39.001
TCDBi3.A.1.112.3 the atp-binding cassette (abc) superfamily

Names & Taxonomyi

Protein namesi
Recommended name:
Lactococcin-A transport/processing ATP-binding protein LcnC (EC:3.4.22.-)
Gene namesi
Name:lcnC
Encoded oniPlasmid pNP20 Publication
OrganismiLactococcus lactis subsp. lactis (Streptococcus lactis)
Taxonomic identifieri1360 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeLactococcus

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei167 – 187HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei197 – 217HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei237 – 257HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei282 – 302HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei307 – 327HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei396 – 416HelicalPROSITE-ProRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000923991 – 715Lactococcin-A transport/processing ATP-binding protein LcnCAdd BLAST715

Structurei

3D structure databases

ProteinModelPortaliQ00564
SMRiQ00564
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 138Peptidase C39PROSITE-ProRule annotationAdd BLAST128
Domaini168 – 450ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST283
Domaini482 – 715ABC transporterPROSITE-ProRule annotationAdd BLAST234

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Family and domain databases

Gene3Di1.20.1560.10, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase
IPR005897 Pept_C39_ABC_bacteriocin
IPR005074 Peptidase_C39
PfamiView protein in Pfam
PF00664 ABC_membrane, 1 hit
PF00005 ABC_tran, 1 hit
PF03412 Peptidase_C39, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
SSF90123 SSF90123, 1 hit
TIGRFAMsiTIGR01193 bacteriocin_ABC, 1 hit
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 1 hit
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit
PS50990 PEPTIDASE_C39, 1 hit

Sequencei

Sequence statusi: Complete.

Q00564-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFKKKNYTS QVDEMDCGCA ALSMILKSYG TEKSLASLRL LAGTTIEGTS
60 70 80 90 100
ALGIKKAAEI LEFSVQALRT DASLFEMKNA PYPFIAHVIK DQKYPHYYVI
110 120 130 140 150
TGANKNSVFI ADPDPTIKMT KLSKEAFLSE WTGISLFLST TPSYHPTKEK
160 170 180 190 200
ASSLLSFIPI ITRQKKVILN IVIASFIVTL INILGSYYLQ SMIDSYIPNA
210 220 230 240 250
LMGTLGIISV GLLLTYIIQQ VLEFAKAFLL NVLSQRLAID VILSYIRHIF
260 270 280 290 300
QLPMSFFSTR RTGEITSRFS DASSILDAIA STILSLFLDL TIVVMTGLIL
310 320 330 340 350
GLQNMQLFLL VLLAIPLYIV VIIIFTPLFE KQNHEVMQTN AVLNSSIIED
360 370 380 390 400
INGIETIKAL ASEQERYQKI DYEFASYLKK AFTLQKSEAI QGLIKAIIQL
410 420 430 440 450
TLSVTILWFG ATLVISQKIT LGQLITFNAL LSYFTNPITN IINLQTKLQK
460 470 480 490 500
ARVANERLNE VYLVPSEFEE KKTELSLSHF NLNMSDISYQ YGFGRKVLSE
510 520 530 540 550
IELSIKENEK LTIVGMSGSG KSTLVKLLVN FFQPTSGTIT LGGIDLQQFD
560 570 580 590 600
KHQLRRLINY LPQQPYIFTG SILDNLLLGA NENASQEEIL KAVELAEIRA
610 620 630 640 650
DIEQMQLGYQ TELSSDASSL SGGQKQRIAL ARALLSPAKI LILDEATSNL
660 670 680 690 700
DMITEKKILK NLLPLDKTII FIAHRLSVAE MSHRIIVVDQ GKVIESGSHV
710
DLLAQNGFYE QLYHN
Length:715
Mass (Da):79,810
Last modified:April 1, 1993 - v1
Checksum:iEF3717ECB0F5B0C4
GO

Sequence cautioni

The sequence AAA92854 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M90969 Genomic DNA Translation: AAA92852.1 Sequence problems.
M90969 Genomic DNA Translation: AAA92854.1 Different initiation.
PIRiB43943

Similar proteinsi

Entry informationi

Entry nameiLCNC_LACLL
AccessioniPrimary (citable) accession number: Q00564
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 1, 1993
Last sequence update: April 1, 1993
Last modified: October 25, 2017
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Plasmid

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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