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UniProtKB - Q00177 (XYNC_EMENI)
Protein
Endo-1,4-beta-xylanase C
Gene
xlnC
Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Status
Functioni
Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
2 PublicationsCatalytic activityi
- Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans. EC:3.2.1.8
pH dependencei
Optimum pH is 4.9.1 Publication
Temperature dependencei
Optimum temperature is 52 degrees Celsius.1 Publication
: xylan degradation Pathwayi
This protein is involved in the pathway xylan degradation, which is part of Glycan degradation.View all proteins of this organism that are known to be involved in the pathway xylan degradation and in Glycan degradation.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 154 | Proton donorBy similarity | 1 | |
Active sitei | 262 | NucleophileBy similarity | 1 |
GO - Molecular functioni
- endo-1,4-beta-xylanase activity Source: UniProtKB
GO - Biological processi
- xylan catabolic process Source: UniProtKB
Keywordsi
Molecular function | Glycosidase, Hydrolase |
Biological process | Carbohydrate metabolism, Polysaccharide degradation, Xylan degradation |
Enzyme and pathway databases
BRENDAi | 3.2.1.8, 517 |
UniPathwayi | UPA00114 |
Protein family/group databases
CAZyi | GH10, Glycoside Hydrolase Family 10 |
Names & Taxonomyi
Protein namesi | Recommended name: Endo-1,4-beta-xylanase C (EC:3.2.1.8)Short name: Xylanase C Alternative name(s): 1,4-beta-D-xylan xylanohydrolase C 34 kDa xylanase Xylanase X34 |
Gene namesi | Name:xlnC ORF Names:AN1818 |
Organismi | Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) |
Taxonomic identifieri | 227321 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Aspergillaceae › Aspergillus › Aspergillus subgen. Nidulantes › |
Proteomesi |
|
Subcellular locationi
Extracellular region or secreted
Extracellular region or secreted
- extracellular region Source: UniProtKB-SubCell
Keywords - Cellular componenti
SecretedPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 24 | By similarityAdd BLAST | 24 | |
ChainiPRO_0000007974 | 25 – 327 | Endo-1,4-beta-xylanase CAdd BLAST | 303 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 25 | Pyrrolidone carboxylic acidBy similarity | 1 | |
Disulfide bondi | 280 ↔ 286 | 1 Publication |
Keywords - PTMi
Disulfide bond, Pyrrolidone carboxylic acidExpressioni
Inductioni
Expressed in presence of xylan and repressed by glucose.1 Publication
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | Q00177 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q00177 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 44 – 325 | GH10PROSITE-ProRule annotationAdd BLAST | 282 |
Sequence similaritiesi
Belongs to the glycosyl hydrolase 10 (cellulase F) family.Curated
Keywords - Domaini
SignalPhylogenomic databases
eggNOGi | ENOG502QSCW, Eukaryota |
HOGENOMi | CLU_020161_2_0_1 |
InParanoidi | Q00177 |
OrthoDBi | 829814at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR044846, GH10 IPR001000, GH10_dom IPR017853, Glycoside_hydrolase_SF |
PANTHERi | PTHR31490, PTHR31490, 1 hit |
Pfami | View protein in Pfam PF00331, Glyco_hydro_10, 1 hit |
PRINTSi | PR00134, GLHYDRLASE10 |
SMARTi | View protein in SMART SM00633, Glyco_10, 1 hit |
SUPFAMi | SSF51445, SSF51445, 1 hit |
PROSITEi | View protein in PROSITE PS51760, GH10_2, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q00177-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVHLKTLAGS AVFASLATAA VLPRQSASLN DLFVAAGKSY FGTCSDQALL
60 70 80 90 100
QNSQNEAIVA SQFGVITPEN SMKWDALEPS QGNFGWSGAD YLVDYATQHN
110 120 130 140 150
KKVRGHTLVW HSQLPSWVSS IGDANTLRSV MTNHINEVVG RYKGKIMHWD
160 170 180 190 200
VVNEIFNEDG TFRNSVFYNL LGEDFVRIAF ETARAADPDA KLYINDYNLD
210 220 230 240 250
SASYAKTQAM ASYVKKWLAE GVPIDGIGSQ AHYSSSHWSS TEAAGALSSL
260 270 280 290 300
ANTGVSEVAI TELDIAGAAS SDYLNLLNAC LNEQKCVGIT VWGVSDKDSW
310 320
RASDSPLLFD GNYQPKDAYN AIVNALS
Sequence cautioni
The sequence CBF85620 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence EAA64983 differs from that shown. Reason: Erroneous gene model prediction.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z49894 Genomic DNA Translation: CAA90075.1 DQ490475 mRNA Translation: ABF50851.1 AACD01000029 Genomic DNA Translation: EAA64983.1 Sequence problems. BN001307 Genomic DNA Translation: CBF85620.1 Sequence problems. |
PIRi | JC5034 |
RefSeqi | XP_659422.1, XM_654330.1 |
Genome annotation databases
EnsemblFungii | EAA64983; EAA64983; AN1818.2 |
GeneIDi | 2874673 |
KEGGi | ani:AN1818.2 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z49894 Genomic DNA Translation: CAA90075.1 DQ490475 mRNA Translation: ABF50851.1 AACD01000029 Genomic DNA Translation: EAA64983.1 Sequence problems. BN001307 Genomic DNA Translation: CBF85620.1 Sequence problems. |
PIRi | JC5034 |
RefSeqi | XP_659422.1, XM_654330.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1TA3 | X-ray | 1.70 | B | 25-327 | [»] | |
SMRi | Q00177 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 227321.Q00177 |
Protein family/group databases
CAZyi | GH10, Glycoside Hydrolase Family 10 |
Genome annotation databases
EnsemblFungii | EAA64983; EAA64983; AN1818.2 |
GeneIDi | 2874673 |
KEGGi | ani:AN1818.2 |
Phylogenomic databases
eggNOGi | ENOG502QSCW, Eukaryota |
HOGENOMi | CLU_020161_2_0_1 |
InParanoidi | Q00177 |
OrthoDBi | 829814at2759 |
Enzyme and pathway databases
UniPathwayi | UPA00114 |
BRENDAi | 3.2.1.8, 517 |
Miscellaneous databases
EvolutionaryTracei | Q00177 |
Family and domain databases
InterProi | View protein in InterPro IPR044846, GH10 IPR001000, GH10_dom IPR017853, Glycoside_hydrolase_SF |
PANTHERi | PTHR31490, PTHR31490, 1 hit |
Pfami | View protein in Pfam PF00331, Glyco_hydro_10, 1 hit |
PRINTSi | PR00134, GLHYDRLASE10 |
SMARTi | View protein in SMART SM00633, Glyco_10, 1 hit |
SUPFAMi | SSF51445, SSF51445, 1 hit |
PROSITEi | View protein in PROSITE PS51760, GH10_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | XYNC_EMENI | |
Accessioni | Q00177Primary (citable) accession number: Q00177 Secondary accession number(s): C8VPM8, Q1HFU9, Q5BCB2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 15, 1998 |
Last sequence update: | November 1, 1996 | |
Last modified: | February 23, 2022 | |
This is version 134 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Glycosyl hydrolases
Classification of glycosyl hydrolase families and list of entries - PATHWAY comments
Index of metabolic and biosynthesis pathways - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families