UniProtKB - P9WQ65 (AMT_MYCTU)
Protein
Probable ammonia channel
Gene
amt
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Functioni
Involved in the uptake of ammonia.By similarity
GO - Molecular functioni
- ammonium transmembrane transporter activity Source: GO_Central
GO - Biological processi
- nitrogen utilization Source: GO_Central
Keywordsi
Biological process | Ammonia transport, Transport |
Enzyme and pathway databases
BioCyci | MTBH37RV:G185E-7172-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Probable ammonia channelAlternative name(s): Ammonia transporter |
Gene namesi | Name:amt Ordered Locus Names:Rv2920c ORF Names:MTCY338.09c |
Organismi | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Taxonomic identifieri | 83332 [NCBI] |
Taxonomic lineagei | Bacteria › Actinobacteria › Corynebacteriales › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex › |
Proteomesi |
|
Organism-specific databases
TubercuListi | Rv2920c |
Subcellular locationi
- Cell membrane Curated; Multi-pass membrane protein Curated
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 16 – 36 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 53 – 73 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 121 – 141 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 150 – 170 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 192 – 212 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 229 – 249 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 257 – 277 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 290 – 310 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 312 – 332 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 344 – 364 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 394 – 414 | HelicalSequence analysisAdd BLAST | 21 |
GO - Cellular componenti
- integral component of plasma membrane Source: GO_Central
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000139758 | 1 – 477 | Probable ammonia channelAdd BLAST | 477 |
Proteomic databases
PaxDbi | P9WQ65 |
PRIDEi | P9WQ65 |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG4105BZU Bacteria ENOG410XNMH LUCA |
KOi | K03320 |
OMAi | AVMACWN |
PhylomeDBi | P9WQ65 |
Family and domain databases
Gene3Di | 1.10.3430.10, 1 hit |
InterProi | View protein in InterPro IPR029020 Ammonium/urea_transptr IPR001905 Ammonium_transpt IPR018047 Ammonium_transpt_CS IPR024041 NH4_transpt_AmtB-like_dom |
Pfami | View protein in Pfam PF00909 Ammonium_transp, 1 hit |
TIGRFAMsi | TIGR00836 amt, 1 hit |
PROSITEi | View protein in PROSITE PS01219 AMMONIUM_TRANSP, 1 hit |
i Sequence
Sequence statusi: Complete.
P9WQ65-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDQFPIMGVP DGGDTAWMLV SSALVLLMTP GLAFFYGGMV RSKSVLNMIM
60 70 80 90 100
MSISAMGVVT VLWALYGYSI AFGDDVGNIA GNPSQYWGLK GLIGVNAVAA
110 120 130 140 150
DPSTQTAAVN IPLAGTLPAT VFVAFQLMFA IITVALISGA VADRLKFGAW
160 170 180 190 200
LLFAGLWATF VYFPVAHWVF AFDGFAAEHG GWIANKLHAI DFAGGTAVHI
210 220 230 240 250
NAGVAALMLA IVLGKRRGWP ATLFRPHNLP FVMLGAALLW FGWYGFNAGS
260 270 280 290 300
ATTANGVAGA TFVTTTIATA AAMLGWLLTE RVRDGKATTL GAASGIVAGL
310 320 330 340 350
VAITPSCSSV NVLGALAVGV SAGVLCALAV GLKFKLGFDD SLDVVGVHLV
360 370 380 390 400
GGLVGTLLVG LLAAPEAPAI NGVAGVSKGL FYGGGFAQLE RQALGACSVL
410 420 430 440 450
VYSGIITLIL ALILKFTIGL RLDAEQESTG IDEAEHAESG YDFAVASGSV
460 470
LPPRVTVEDS RNGIQERIGQ KVEAEPK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL123456 Genomic DNA Translation: CCP45722.1 |
PIRi | H70747 |
RefSeqi | NP_217436.1, NC_000962.3 WP_003899540.1, NZ_NVQJ01000006.1 |
Genome annotation databases
EnsemblBacteriai | CCP45722; CCP45722; Rv2920c |
GeneIDi | 887683 |
KEGGi | mtu:Rv2920c mtv:RVBD_2920c |
PATRICi | fig|83332.111.peg.3249 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL123456 Genomic DNA Translation: CCP45722.1 |
PIRi | H70747 |
RefSeqi | NP_217436.1, NC_000962.3 WP_003899540.1, NZ_NVQJ01000006.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 83332.Rv2920c |
Proteomic databases
PaxDbi | P9WQ65 |
PRIDEi | P9WQ65 |
Genome annotation databases
EnsemblBacteriai | CCP45722; CCP45722; Rv2920c |
GeneIDi | 887683 |
KEGGi | mtu:Rv2920c mtv:RVBD_2920c |
PATRICi | fig|83332.111.peg.3249 |
Organism-specific databases
TubercuListi | Rv2920c |
Phylogenomic databases
eggNOGi | ENOG4105BZU Bacteria ENOG410XNMH LUCA |
KOi | K03320 |
OMAi | AVMACWN |
PhylomeDBi | P9WQ65 |
Enzyme and pathway databases
BioCyci | MTBH37RV:G185E-7172-MONOMER |
Family and domain databases
Gene3Di | 1.10.3430.10, 1 hit |
InterProi | View protein in InterPro IPR029020 Ammonium/urea_transptr IPR001905 Ammonium_transpt IPR018047 Ammonium_transpt_CS IPR024041 NH4_transpt_AmtB-like_dom |
Pfami | View protein in Pfam PF00909 Ammonium_transp, 1 hit |
TIGRFAMsi | TIGR00836 amt, 1 hit |
PROSITEi | View protein in PROSITE PS01219 AMMONIUM_TRANSP, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | AMT_MYCTU | |
Accessioni | P9WQ65Primary (citable) accession number: P9WQ65 Secondary accession number(s): L0TDY4, P63519, Q10968 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 16, 2014 |
Last sequence update: | April 16, 2014 | |
Last modified: | November 13, 2019 | |
This is version 35 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Complete proteome, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - Mycobacterium tuberculosis strains ATCC 25618 / H37Rv and CDC 1551 / Oshkosh
Mycobacterium tuberculosis strains ATCC 25618 / H37Rv and CDC 1551 / Oshkosh: entries and gene names