UniProtKB - P9WQ31 (Y1319_MYCTU)
Protein
Uncharacterized protein Rv1319c
Gene
Rv1319c
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Functioni
GO - Molecular functioni
- adenylate cyclase activity Source: MTBBASE
GO - Biological processi
- cAMP biosynthetic process Source: MTBBASE
- intracellular signal transduction Source: InterPro
Names & Taxonomyi
Protein namesi | Recommended name: Uncharacterized protein Rv1319c |
Gene namesi | Ordered Locus Names:Rv1319c ORF Names:MTCY130.04c |
Organismi | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Taxonomic identifieri | 83332 [NCBI] |
Taxonomic lineagei | Bacteria › Actinobacteria › Corynebacteriales › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex › |
Proteomesi |
|
Organism-specific databases
TubercuListi | Rv1319c |
Subcellular locationi
- Cell membrane Curated; Multi-pass membrane protein Curated
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 63 – 83 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 90 – 110 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 143 – 163 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 168 – 188 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 226 – 246 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 258 – 278 | HelicalSequence analysisAdd BLAST | 21 |
GO - Cellular componenti
- extracellular region Source: MTBBASE
- integral component of membrane Source: UniProtKB-KW
- plasma membrane Source: UniProtKB-SubCell
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000195754 | 1 – 535 | Uncharacterized protein Rv1319cAdd BLAST | 535 |
Proteomic databases
PaxDbi | P9WQ31 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 279 – 330 | HAMPPROSITE-ProRule annotationAdd BLAST | 52 | |
Domaini | 362 – 486 | Guanylate cyclasePROSITE-ProRule annotationAdd BLAST | 125 |
Sequence similaritiesi
Belongs to the adenylyl cyclase class-3 family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG2114, Bacteria COG2972, Bacteria |
OMAi | WITRRTI |
PhylomeDBi | P9WQ31 |
Family and domain databases
CDDi | cd06225, HAMP, 1 hit |
Gene3Di | 3.30.70.1230, 1 hit |
InterProi | View protein in InterPro IPR001054, A/G_cyclase IPR003660, HAMP_dom IPR029787, Nucleotide_cyclase |
Pfami | View protein in Pfam PF00211, Guanylate_cyc, 1 hit PF00672, HAMP, 1 hit |
SMARTi | View protein in SMART SM00044, CYCc, 1 hit SM00304, HAMP, 1 hit |
SUPFAMi | SSF55073, SSF55073, 1 hit |
PROSITEi | View protein in PROSITE PS50125, GUANYLATE_CYCLASE_2, 1 hit PS50885, HAMP, 1 hit |
i Sequence
Sequence statusi: Complete.
P9WQ31-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPAKKTMAQR LGQALETMTR QCGQLPETPA YGSWLLGRVS ESPSRRWVRI
60 70 80 90 100
KRIVTVYIMT ANLTGIVVAL LVVTFAFPVP SIYTDAPWWV TFGVAPAYAT
110 120 130 140 150
LALAIGTYWI TTRIVRASIR WAIEERAPSQ ADGRNTLLLP FRVAAVHLIL
160 170 180 190 200
WDIGGALLAT LYGLANRVFV TIILFSVTIC GVLVATNCYL FTEFALRPVA
210 220 230 240 250
AKALEAGRPP RRFAPGIMGR TMTVWSLGSG VPVTGIATTA LYVLLVHNLT
260 270 280 290 300
ETQLASAVLI LSITTLIFGF LVMWILAWLT AAPVRVVRAA LKRVEQGDLR
310 320 330 340 350
GDLVVFDGTE LGELQRGFNA MVNGLRERER VRDLFGRHVG REVAAAAERE
360 370 380 390 400
RPQLGGEDRH AAVVFVDIVG STQLVDNQPA AHVVKLLNRF FAIVVNEVDR
410 420 430 440 450
HHGLINKFAG DAALAIFGAP NRLDRPEDAA LAAARAIADR LANEMPEVQA
460 470 480 490 500
GIGVAAGQIV AGNVGAKQRF EYTVVGKPVN QAARLCELAK SHPARLLASS
510 520 530
DTLHAASETE RAHWSLGETV TLRGHEQPTR LAVPT
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL123456 Genomic DNA Translation: CCP44076.1 |
PIRi | C70769 |
RefSeqi | NP_215835.1, NC_000962.3 WP_003406867.1, NZ_NVQJ01000059.1 |
Genome annotation databases
EnsemblBacteriai | CCP44076; CCP44076; Rv1319c |
GeneIDi | 23492528 886911 |
KEGGi | mtu:Rv1319c mtv:RVBD_1319c |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL123456 Genomic DNA Translation: CCP44076.1 |
PIRi | C70769 |
RefSeqi | NP_215835.1, NC_000962.3 WP_003406867.1, NZ_NVQJ01000059.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 83332.Rv1319c |
Proteomic databases
PaxDbi | P9WQ31 |
Genome annotation databases
EnsemblBacteriai | CCP44076; CCP44076; Rv1319c |
GeneIDi | 23492528 886911 |
KEGGi | mtu:Rv1319c mtv:RVBD_1319c |
Organism-specific databases
TubercuListi | Rv1319c |
Phylogenomic databases
eggNOGi | COG2114, Bacteria COG2972, Bacteria |
OMAi | WITRRTI |
PhylomeDBi | P9WQ31 |
Family and domain databases
CDDi | cd06225, HAMP, 1 hit |
Gene3Di | 3.30.70.1230, 1 hit |
InterProi | View protein in InterPro IPR001054, A/G_cyclase IPR003660, HAMP_dom IPR029787, Nucleotide_cyclase |
Pfami | View protein in Pfam PF00211, Guanylate_cyc, 1 hit PF00672, HAMP, 1 hit |
SMARTi | View protein in SMART SM00044, CYCc, 1 hit SM00304, HAMP, 1 hit |
SUPFAMi | SSF55073, SSF55073, 1 hit |
PROSITEi | View protein in PROSITE PS50125, GUANYLATE_CYCLASE_2, 1 hit PS50885, HAMP, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Y1319_MYCTU | |
Accessioni | P9WQ31Primary (citable) accession number: P9WQ31 Secondary accession number(s): L0T6A5, P0A4Y2, Q10632 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 16, 2014 |
Last sequence update: | April 16, 2014 | |
Last modified: | December 2, 2020 | |
This is version 34 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families