UniProtKB - P9WPM1 (CP139_MYCTU)
Protein
Putative cytochrome P450 139
Gene
cyp139
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Functioni
Cofactori
hemeBy similarity
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 372 | Iron (heme axial ligand)By similarity | 1 |
GO - Molecular functioni
- heme binding Source: InterPro
- iron ion binding Source: InterPro
- monooxygenase activity Source: UniProtKB-KW
- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Source: InterPro
Keywordsi
Molecular function | Monooxygenase, Oxidoreductase |
Ligand | Heme, Iron, Metal-binding |
Enzyme and pathway databases
BioCyci | MTBH37RV:G185E-5856-MONOMER |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:cyp139 Ordered Locus Names:Rv1666c ORF Names:MTV047.02c |
Organismi | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Taxonomic identifieri | 83332 [NCBI] |
Taxonomic lineagei | Bacteria › Actinobacteria › Corynebacteriales › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex › |
Proteomesi |
|
Organism-specific databases
TubercuListi | Rv1666c |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000052300 | 1 – 430 | Putative cytochrome P450 139Add BLAST | 430 |
Proteomic databases
PaxDbi | P9WPM1 |
Family & Domainsi
Sequence similaritiesi
Belongs to the cytochrome P450 family.Curated
Phylogenomic databases
eggNOGi | ENOG4105JZI Bacteria COG2124 LUCA |
OMAi | PEAIFFH |
PhylomeDBi | P9WPM1 |
Family and domain databases
Gene3Di | 1.10.630.10, 1 hit |
InterProi | View protein in InterPro IPR001128 Cyt_P450 IPR017972 Cyt_P450_CS IPR002403 Cyt_P450_E_grp-IV IPR036396 Cyt_P450_sf |
Pfami | View protein in Pfam PF00067 p450, 1 hit |
PRINTSi | PR00465 EP450IV PR00385 P450 |
SUPFAMi | SSF48264 SSF48264, 1 hit |
PROSITEi | View protein in PROSITE PS00086 CYTOCHROME_P450, 1 hit |
i Sequence
Sequence statusi: Complete.
P9WPM1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRYPLGEALL ALYRWRGPLI NAGVGGHGYT YLLGAEANRF VFANADAFSW
60 70 80 90 100
SQTFESLVPV DGPTALIVSD GADHRRRRSV VAPGLRHHHV QRYVATMVSN
110 120 130 140 150
IDTVIDGWQP GQRLDIYQEL RSAVRRSTAE SLFGQRLAVH SDFLGEQLQP
160 170 180 190 200
LLDLTRRPPQ VMRLQQRVNS PGWRRAMAAR KRIDDLIDAQ IADARTAPRP
210 220 230 240 250
DDHMLTTLIS GCSEEGTTLS DNEIRDSIVS LITAGYETTS GALAWAIYAL
260 270 280 290 300
LTVPGTWESA ASEVARVLGG RVPAADDLSA LTYLNGVVHE TLRLYSPGVI
310 320 330 340 350
SARRVLRDLW FDGHRIRAGR LLIFSAYVTH RLPEIWPEPT EFRPLRWDPN
360 370 380 390 400
AADYRKPAPH EFIPFSGGLH RCIGAVMATT EMTVILARLV ARAMLQLPAQ
410 420 430
RTHRIRAANF AALRPWPGLT VEIRKSAPAQ
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | GQ900520 Genomic DNA Translation: ACX47919.1 AL123456 Genomic DNA Translation: CCP44431.1 |
PIRi | D70985 |
RefSeqi | NP_216182.1, NC_000962.3 WP_003901231.1, NZ_NVQJ01000010.1 |
Genome annotation databases
EnsemblBacteriai | CCP44431; CCP44431; Rv1666c |
GeneIDi | 885528 |
KEGGi | mtu:Rv1666c mtv:RVBD_1666c |
PATRICi | fig|83332.111.peg.1852 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | GQ900520 Genomic DNA Translation: ACX47919.1 AL123456 Genomic DNA Translation: CCP44431.1 |
PIRi | D70985 |
RefSeqi | NP_216182.1, NC_000962.3 WP_003901231.1, NZ_NVQJ01000010.1 |
3D structure databases
SMRi | P9WPM1 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 83332.Rv1666c |
Proteomic databases
PaxDbi | P9WPM1 |
Genome annotation databases
EnsemblBacteriai | CCP44431; CCP44431; Rv1666c |
GeneIDi | 885528 |
KEGGi | mtu:Rv1666c mtv:RVBD_1666c |
PATRICi | fig|83332.111.peg.1852 |
Organism-specific databases
TubercuListi | Rv1666c |
Phylogenomic databases
eggNOGi | ENOG4105JZI Bacteria COG2124 LUCA |
OMAi | PEAIFFH |
PhylomeDBi | P9WPM1 |
Enzyme and pathway databases
BioCyci | MTBH37RV:G185E-5856-MONOMER |
Family and domain databases
Gene3Di | 1.10.630.10, 1 hit |
InterProi | View protein in InterPro IPR001128 Cyt_P450 IPR017972 Cyt_P450_CS IPR002403 Cyt_P450_E_grp-IV IPR036396 Cyt_P450_sf |
Pfami | View protein in Pfam PF00067 p450, 1 hit |
PRINTSi | PR00465 EP450IV PR00385 P450 |
SUPFAMi | SSF48264 SSF48264, 1 hit |
PROSITEi | View protein in PROSITE PS00086 CYTOCHROME_P450, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CP139_MYCTU | |
Accessioni | P9WPM1Primary (citable) accession number: P9WPM1 Secondary accession number(s): D0EW72 P63719 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 16, 2014 |
Last sequence update: | April 16, 2014 | |
Last modified: | October 16, 2019 | |
This is version 38 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Complete proteome, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - Mycobacterium tuberculosis strains ATCC 25618 / H37Rv and CDC 1551 / Oshkosh
Mycobacterium tuberculosis strains ATCC 25618 / H37Rv and CDC 1551 / Oshkosh: entries and gene names