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UniProtKB - P9WPE3 (CINAL_MYCTU)

Entry version 26 (18 Sep 2019)
Sequence version 1 (16 Apr 2014)
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Protein

CinA-like protein

Gene

cinA

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Reviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		MTBH37RV:G185E-6098-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
CinA-like proteinUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:cinAUniRule annotation
Ordered Locus Names:Rv1901
ORF Names:MTCY180.17c
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83332 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Actinobacteria › Corynebacteriales › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001584 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

Organism-specific databases

Mycobacterium tuberculosis strain H37Rv genome database

More...TubercuListi		Rv1901

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

Complete GO annotation on QuickGO ...

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001567701 – 430CinA-like proteinAdd BLAST430

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P9WPE3

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		83332.Rv1901

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P9WPE3

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CinA family.UniRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG4105CEV Bacteria
COG1058 LUCA
COG1546 LUCA

KEGG Orthology (KO)

More...KOi		K03742

Identification of Orthologs from Complete Genome Data

More...OMAi		PGVPYEM

Database for complete collections of gene phylogenies

More...PhylomeDBi		P9WPE3

Family and domain databases

Conserved Domains Database

More...CDDi		cd00885 cinA, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.40.980.10, 1 hit
3.90.950.20, 1 hit

HAMAP database of protein families

More...HAMAPi		MF_00226_B CinA_B, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR036653 CinA-like_C
IPR008136 CinA_C
IPR008135 Competence-induced_CinA
IPR036425 MoaB/Mog-like_dom_sf
IPR001453 MoaB/Mog_dom

Pfam protein domain database

More...Pfami		View protein in Pfam
PF02464 CinA, 1 hit
PF00994 MoCF_biosynth, 1 hit

PIRSF; a whole-protein classification database

More...PIRSFi		PIRSF006728 CinA, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00852 MoCF_biosynth, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF142433 SSF142433, 1 hit
SSF53218 SSF53218, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR00200 cinA_nterm, 1 hit
TIGR00199 PncC_domain, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P9WPE3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAVSARAGIV ITGTEVLTGR VQDRNGPWIA DRLLELGVEL AHITICGDRP 
        60         70         80         90        100
ADIEAQLRFM AEQGVDLIVT SGGLGPTADD MTVEVVARYC GRELVLDDEL 
       110        120        130        140        150
ENRIANILKK LMGRNPAIEP ANFDSIRAAN RKQAMIPAGS QVIDPVGTAP 
       160        170        180        190        200
GLVVPGRPAV MVLPGPPREL QPIWSKAIQT APVQDAIAGR TTYRQETIRI 
       210        220        230        240        250
FGLPESSLAD TLRDAEAAIP GFDLVEITTC LRRGEIEMVT RFEPNAAQVY 
       260        270        280        290        300
TQLARLLRDR HGHQVYSEDG ASVDELVAKL LTGRRIATAE SCTAGLLAAR 
       310        320        330        340        350
LTDRPGSSKY VAGAVVAYSN EAKAQLLGVD PALIEAHGAV SEPVAQAMAA 
       360        370        380        390        400
GALQGFGADT ATAITGIAGP SGGTPEKPVG TVCFTVLLDD GRTTTRTVRL 
       410        420        430
PGNRSDIRER STTVAMHLLR RTLSGIPGSP
Length:430
Mass (Da):45,512
Last modified:April 16, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC0E479CDD8C2C182
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AL123456 Genomic DNA Translation: CCP44668.1

Protein sequence database of the Protein Information Resource

More...PIRi		B70518

NCBI Reference Sequences

More...RefSeqi		NP_216417.1, NC_000962.3
WP_003900426.1, NZ_NVQJ01000034.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		CCP44668; CCP44668; Rv1901

Database of genes from NCBI RefSeq genomes

More...GeneIDi		885149

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mtu:Rv1901
mtv:RVBD_1901

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL123456 Genomic DNA Translation: CCP44668.1
PIRiB70518
RefSeqiNP_216417.1, NC_000962.3
WP_003900426.1, NZ_NVQJ01000034.1

3D structure databases

SMRiP9WPE3
ModBaseiSearch...

Protein-protein interaction databases

STRINGi83332.Rv1901

Proteomic databases

PaxDbiP9WPE3

Genome annotation databases

EnsemblBacteriaiCCP44668; CCP44668; Rv1901
GeneIDi885149
KEGGimtu:Rv1901
mtv:RVBD_1901

Organism-specific databases

TubercuListiRv1901

Phylogenomic databases

eggNOGiENOG4105CEV Bacteria
COG1058 LUCA
COG1546 LUCA
KOiK03742
OMAiPGVPYEM
PhylomeDBiP9WPE3

Enzyme and pathway databases

BioCyciMTBH37RV:G185E-6098-MONOMER

Family and domain databases

CDDicd00885 cinA, 1 hit
Gene3Di3.40.980.10, 1 hit
3.90.950.20, 1 hit
HAMAPiMF_00226_B CinA_B, 1 hit
InterProiView protein in InterPro
IPR036653 CinA-like_C
IPR008136 CinA_C
IPR008135 Competence-induced_CinA
IPR036425 MoaB/Mog-like_dom_sf
IPR001453 MoaB/Mog_dom
PfamiView protein in Pfam
PF02464 CinA, 1 hit
PF00994 MoCF_biosynth, 1 hit
PIRSFiPIRSF006728 CinA, 1 hit
SMARTiView protein in SMART
SM00852 MoCF_biosynth, 1 hit
SUPFAMiSSF142433 SSF142433, 1 hit
SSF53218 SSF53218, 1 hit
TIGRFAMsiTIGR00200 cinA_nterm, 1 hit
TIGR00199 PncC_domain, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCINAL_MYCTU
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P9WPE3
Secondary accession number(s): L0T877, O07731, P63775
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 16, 2014
Last sequence update: April 16, 2014
Last modified: September 18, 2019
This is version 26 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Mycobacterium tuberculosis strains ATCC 25618 / H37Rv and CDC 1551 / Oshkosh
    Mycobacterium tuberculosis strains ATCC 25618 / H37Rv and CDC 1551 / Oshkosh: entries and gene names
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