UniProtKB - P9WN80 (GLPD1_MYCTO)
Protein
Glycerol-3-phosphate dehydrogenase 1
Gene
glpD1
Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Status
Functioni
Catalytic activityi
- EC:1.1.5.3
Cofactori
FADBy similarity
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 28 – 56 | FADBy similarityAdd BLAST | 29 |
GO - Molecular functioni
- sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity Source: UniProtKB-EC
GO - Biological processi
- glycerol-3-phosphate metabolic process Source: InterPro
- glycerol metabolic process Source: UniProtKB-KW
Keywordsi
Molecular function | Oxidoreductase |
Biological process | Glycerol metabolism |
Ligand | FAD, Flavoprotein |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:glpD1 Synonyms:glpD Ordered Locus Names:MT2309 |
Organismi | Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) |
Taxonomic identifieri | 83331 [NCBI] |
Taxonomic lineagei | Bacteria › Actinobacteria › Corynebacteriales › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex › |
Proteomesi |
|
Subcellular locationi
Cytoplasm and Cytosol
- Cytoplasm By similarity
Other locations
- glycerol-3-phosphate dehydrogenase complex Source: InterPro
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000427173 | 1 – 516 | Glycerol-3-phosphate dehydrogenase 1Add BLAST | 516 |
Family & Domainsi
Sequence similaritiesi
Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.Curated
Phylogenomic databases
HOGENOMi | CLU_015740_5_1_11 |
Family and domain databases
Gene3Di | 1.10.8.870, 1 hit 3.50.50.60, 1 hit |
InterProi | View protein in InterPro IPR031656, DAO_C IPR038299, DAO_C_sf IPR006076, FAD-dep_OxRdtase IPR036188, FAD/NAD-bd_sf IPR000447, G3P_DH_FAD-dep |
PANTHERi | PTHR11985, PTHR11985, 1 hit |
Pfami | View protein in Pfam PF01266, DAO, 1 hit PF16901, DAO_C, 1 hit |
PRINTSi | PR01001, FADG3PDH |
SUPFAMi | SSF51905, SSF51905, 1 hit |
PROSITEi | View protein in PROSITE PS00977, FAD_G3PDH_1, 1 hit PS00978, FAD_G3PDH_2, 1 hit |
i Sequence
Sequence statusi: Complete.
P9WN80-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLMPHSAALN AARRSADLTA LADGGALDVI VIGGGITGVG IALDAATRGL
60 70 80 90 100
TVALVEKHDL AFGTSRWSSK LVHGGLRYLA SGNVGIARRS AVERGILMTR
110 120 130 140 150
NAPHLVHAMP QLVPLLPSMG HTKRALVRAG FLAGDALRVL AGTPAATLPR
160 170 180 190 200
SRRIPASRVV EIAPTVRRDG LDGGLLAYDG QLIDDARLVM AVARTAAQHG
210 220 230 240 250
ARILTYVGAS NVTGTSVELT DRRTRQSFAL SARAVINAAG VWAGEIDPSL
260 270 280 290 300
RLRPSRGTHL VFDAKSFANP TAALTIPIPG ELNRFVFAMP EQLGRIYLGL
310 320 330 340 350
TDEDAPGPIP DVPQPSSEEI TFLLDTVNTA LGTAVGTKDV IGAYAGLRPL
360 370 380 390 400
IDTGGAGVQG RTADVSRDHA VFESPSGVIS VVGGKLTEYR YMAEDVLNRA
410 420 430 440 450
ITLRHLRAAK CRTRNLPLIG APANPGPAPG SGAGLPESLV ARYGAEAANV
460 470 480 490 500
AAAATCERPT EPVADGIDVT RAEFEYAVTH EGALDVDDIL DRRTRIGLVP
510
RDRERVVAVA KEFLSR
Sequence cautioni
The sequence AAK46593 differs from that shown. Reason: Erroneous initiation.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE000516 Genomic DNA Translation: AAK46593.1 Different initiation. |
PIRi | E70779 |
RefSeqi | WP_003411591.1, NZ_KK341227.1 |
Genome annotation databases
EnsemblBacteriai | AAK46593; AAK46593; MT2309 |
KEGGi | mtc:MT2309 |
PATRICi | fig|83331.31.peg.2486 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE000516 Genomic DNA Translation: AAK46593.1 Different initiation. |
PIRi | E70779 |
RefSeqi | WP_003411591.1, NZ_KK341227.1 |
3D structure databases
SMRi | P9WN80 |
ModBasei | Search... |
Genome annotation databases
EnsemblBacteriai | AAK46593; AAK46593; MT2309 |
KEGGi | mtc:MT2309 |
PATRICi | fig|83331.31.peg.2486 |
Phylogenomic databases
HOGENOMi | CLU_015740_5_1_11 |
Family and domain databases
Gene3Di | 1.10.8.870, 1 hit 3.50.50.60, 1 hit |
InterProi | View protein in InterPro IPR031656, DAO_C IPR038299, DAO_C_sf IPR006076, FAD-dep_OxRdtase IPR036188, FAD/NAD-bd_sf IPR000447, G3P_DH_FAD-dep |
PANTHERi | PTHR11985, PTHR11985, 1 hit |
Pfami | View protein in Pfam PF01266, DAO, 1 hit PF16901, DAO_C, 1 hit |
PRINTSi | PR01001, FADG3PDH |
SUPFAMi | SSF51905, SSF51905, 1 hit |
PROSITEi | View protein in PROSITE PS00977, FAD_G3PDH_1, 1 hit PS00978, FAD_G3PDH_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | GLPD1_MYCTO | |
Accessioni | P9WN80Primary (citable) accession number: P9WN80 Secondary accession number(s): L0T922, P64182, Q10502 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 16, 2014 |
Last sequence update: | April 16, 2014 | |
Last modified: | February 10, 2021 | |
This is version 35 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |