UniProtKB - P9WN79 (GLPD2_MYCTU)
Protein
Glycerol-3-phosphate dehydrogenase 2
Gene
glpD2
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Functioni
Catalytic activityi
- EC:1.1.5.3
Cofactori
FADBy similarity
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 37 – 65 | FADBy similarityAdd BLAST | 29 |
GO - Molecular functioni
- glycerol-3-phosphate dehydrogenase (quinone) activity Source: GO_Central
- sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity Source: UniProtKB-EC
GO - Biological processi
- glycerol-3-phosphate catabolic process Source: GO_Central
- glycerol metabolic process Source: UniProtKB-KW
Keywordsi
Molecular function | Oxidoreductase |
Biological process | Glycerol metabolism |
Ligand | FAD, Flavoprotein |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:glpD2 Ordered Locus Names:Rv3302c ORF Names:MTCI418A.04c, MTV016.01c |
Organismi | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Taxonomic identifieri | 83332 [NCBI] |
Taxonomic lineagei | Bacteria › Actinobacteria › Corynebacteriales › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex › |
Proteomesi |
|
Organism-specific databases
TubercuListi | Rv3302c |
Subcellular locationi
Cytoplasm and Cytosol
- Cytoplasm By similarity
Plasma Membrane
- plasma membrane Source: MTBBASE
Other locations
- glycerol-3-phosphate dehydrogenase complex Source: InterPro
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000126102 | 1 – 585 | Glycerol-3-phosphate dehydrogenase 2Add BLAST | 585 |
Proteomic databases
PaxDbi | P9WN79 |
Family & Domainsi
Sequence similaritiesi
Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.Curated
Phylogenomic databases
eggNOGi | COG0578, Bacteria |
OMAi | AHGFSKT |
PhylomeDBi | P9WN79 |
Family and domain databases
Gene3Di | 1.10.8.870, 1 hit 3.50.50.60, 1 hit |
InterProi | View protein in InterPro IPR031656, DAO_C IPR038299, DAO_C_sf IPR006076, FAD-dep_OxRdtase IPR036188, FAD/NAD-bd_sf IPR000447, G3P_DH_FAD-dep |
PANTHERi | PTHR11985, PTHR11985, 1 hit |
Pfami | View protein in Pfam PF01266, DAO, 1 hit PF16901, DAO_C, 1 hit |
PRINTSi | PR01001, FADG3PDH |
SUPFAMi | SSF51905, SSF51905, 1 hit |
PROSITEi | View protein in PROSITE PS00977, FAD_G3PDH_1, 1 hit PS00978, FAD_G3PDH_2, 1 hit |
i Sequence
Sequence statusi: Complete.
P9WN79-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSNPIQAPDG GQGWPAAALG PAQRAVAWKR LGTEQFDVVV IGGGVVGSGC
60 70 80 90 100
ALDAATRGLK VALVEARDLA SGTSSRSSKM FHGGLRYLEQ LEFGLVREAL
110 120 130 140 150
YERELSLTTL APHLVKPLPF LFPLTKRWWE RPYIAAGIFL YDRLGGAKSV
160 170 180 190 200
PAQRHFTRAG ALRLSPGLKR SSLIGGIRYY DTVVDDARHT MTVARTAAHY
210 220 230 240 250
GAVVRCSTQV VALLREGDRV IGVGVRDSEN GAVAEVRGHV VVNATGVWTD
260 270 280 290 300
EIQALSKQRG RFQVRASKGV HVVVPRDRIV SDVAMILRTE KSVMFVIPWG
310 320 330 340 350
SHWIIGTTDT DWNLDLAHPA ATKADIDYIL GTVNAVLATP LTHADIDGVY
360 370 380 390 400
AGLRPLLAGE SDDTSKLSRE HAVAVPAAGL VAIAGGKYTT YRVMAADAID
410 420 430 440 450
AAVQFIPARV APSITEKVSL LGADGYFALV NQAEHVGALQ GLHPYRVRHL
460 470 480 490 500
LDRYGSLISD VLAMAASDPS LLSPITEAPG YLKVEAAYAA AAEGALHLED
510 520 530 540 550
ILARRMRISI EYPHRGVDCA REVAEVVAPV LGWTAADIDR EVANYMARVE
560 570 580
AEVLSQAQPD DVSADMLRAS APEARAEILE PVPLD
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL123456 Genomic DNA Translation: CCP46121.1 |
PIRi | H70533 |
RefSeqi | NP_217819.1, NC_000962.3 WP_003417217.1, NZ_NVQJ01000003.1 |
Genome annotation databases
GeneIDi | 887211 |
KEGGi | mtu:Rv3302c |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL123456 Genomic DNA Translation: CCP46121.1 |
PIRi | H70533 |
RefSeqi | NP_217819.1, NC_000962.3 WP_003417217.1, NZ_NVQJ01000003.1 |
3D structure databases
SMRi | P9WN79 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 83332.Rv3302c |
Proteomic databases
PaxDbi | P9WN79 |
Genome annotation databases
GeneIDi | 887211 |
KEGGi | mtu:Rv3302c |
Organism-specific databases
TubercuListi | Rv3302c |
Phylogenomic databases
eggNOGi | COG0578, Bacteria |
OMAi | AHGFSKT |
PhylomeDBi | P9WN79 |
Family and domain databases
Gene3Di | 1.10.8.870, 1 hit 3.50.50.60, 1 hit |
InterProi | View protein in InterPro IPR031656, DAO_C IPR038299, DAO_C_sf IPR006076, FAD-dep_OxRdtase IPR036188, FAD/NAD-bd_sf IPR000447, G3P_DH_FAD-dep |
PANTHERi | PTHR11985, PTHR11985, 1 hit |
Pfami | View protein in Pfam PF01266, DAO, 1 hit PF16901, DAO_C, 1 hit |
PRINTSi | PR01001, FADG3PDH |
SUPFAMi | SSF51905, SSF51905, 1 hit |
PROSITEi | View protein in PROSITE PS00977, FAD_G3PDH_1, 1 hit PS00978, FAD_G3PDH_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | GLPD2_MYCTU | |
Accessioni | P9WN79Primary (citable) accession number: P9WN79 Secondary accession number(s): L0TDR3, O07168, P64184 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 16, 2014 |
Last sequence update: | April 16, 2014 | |
Last modified: | April 7, 2021 | |
This is version 37 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families