UniProtKB - P9WMW3 (Y2581_MYCTU)
Protein
Uncharacterized protein Rv2581c
Gene
Rv2581c
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Functioni
Cofactori
Zn2+By similarityNote: Binds 2 Zn2+ ions per subunit.By similarity
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 57 | Zinc 1; via tele nitrogenBy similarity | 1 | |
Metal bindingi | 59 | Zinc 1; via pros nitrogenBy similarity | 1 | |
Metal bindingi | 61 | Zinc 2By similarity | 1 | |
Metal bindingi | 62 | Zinc 2; via tele nitrogenBy similarity | 1 | |
Metal bindingi | 138 | Zinc 1; via tele nitrogenBy similarity | 1 | |
Metal bindingi | 162 | Zinc 1By similarity | 1 | |
Metal bindingi | 162 | Zinc 2By similarity | 1 | |
Metal bindingi | 203 | Zinc 2; via tele nitrogenBy similarity | 1 |
GO - Molecular functioni
- hydrolase activity Source: UniProtKB-KW
- metal ion binding Source: UniProtKB-KW
Keywordsi
Molecular function | Hydrolase |
Ligand | Metal-binding, Zinc |
Enzyme and pathway databases
BioCyci | MTBH37RV:G185E-6823-MONOMER |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Ordered Locus Names:Rv2581c ORF Names:MTCY227.20 |
Organismi | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Taxonomic identifieri | 83332 [NCBI] |
Taxonomic lineagei | Bacteria › Actinobacteria › Corynebacteriales › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex › |
Proteomesi |
|
Organism-specific databases
TubercuListi | Rv2581c |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000192361 | 1 – 224 | Uncharacterized protein Rv2581cAdd BLAST | 224 |
Proteomic databases
PaxDbi | P9WMW3 |
PRIDEi | P9WMW3 |
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
eggNOGi | ENOG4107VMB Bacteria ENOG4110GCR LUCA |
KOi | K01069 |
OMAi | GAWGTNC |
PhylomeDBi | P9WMW3 |
Family and domain databases
Gene3Di | 3.60.15.10, 1 hit |
InterProi | View protein in InterPro IPR001279 Metallo-B-lactamas IPR036866 RibonucZ/Hydroxyglut_hydro |
Pfami | View protein in Pfam PF00753 Lactamase_B, 1 hit |
SMARTi | View protein in SMART SM00849 Lactamase_B, 1 hit |
SUPFAMi | SSF56281 SSF56281, 1 hit |
i Sequence
Sequence statusi: Complete.
P9WMW3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLITGFPAGL LACNCYVLAE RPGTDAVIVD PGQGAMGTLR RILDKNRLTP
60 70 80 90 100
AAVLLTHGHI DHIWSAQKVS DTFGCPTYVH PADRFMLTDP IYGLGPRIAQ
110 120 130 140 150
LVAGAFFREP KQVVELDRDG DKIDLGGISV NIDHTPGHTR GSVVFRVLQA
160 170 180 190 200
TNNDKDIVFT GDTLFERAIG RTDLAGGSGR DLLRSIVDKL LVLDDSTVVL
210 220
PGHGNSTTIG AERRFNPFLE GLSR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL123456 Genomic DNA Translation: CCP45377.1 |
PIRi | D70725 |
RefSeqi | NP_217097.1, NC_000962.3 WP_003413366.1, NZ_NVQJ01000023.1 |
Genome annotation databases
EnsemblBacteriai | CCP45377; CCP45377; Rv2581c |
GeneIDi | 888217 |
KEGGi | mtu:Rv2581c mtv:RVBD_2581c |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL123456 Genomic DNA Translation: CCP45377.1 |
PIRi | D70725 |
RefSeqi | NP_217097.1, NC_000962.3 WP_003413366.1, NZ_NVQJ01000023.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 83332.Rv2581c |
Proteomic databases
PaxDbi | P9WMW3 |
PRIDEi | P9WMW3 |
Genome annotation databases
EnsemblBacteriai | CCP45377; CCP45377; Rv2581c |
GeneIDi | 888217 |
KEGGi | mtu:Rv2581c mtv:RVBD_2581c |
Organism-specific databases
TubercuListi | Rv2581c |
Phylogenomic databases
eggNOGi | ENOG4107VMB Bacteria ENOG4110GCR LUCA |
KOi | K01069 |
OMAi | GAWGTNC |
PhylomeDBi | P9WMW3 |
Enzyme and pathway databases
BioCyci | MTBH37RV:G185E-6823-MONOMER |
Family and domain databases
Gene3Di | 3.60.15.10, 1 hit |
InterProi | View protein in InterPro IPR001279 Metallo-B-lactamas IPR036866 RibonucZ/Hydroxyglut_hydro |
Pfami | View protein in Pfam PF00753 Lactamase_B, 1 hit |
SMARTi | View protein in SMART SM00849 Lactamase_B, 1 hit |
SUPFAMi | SSF56281 SSF56281, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Y2581_MYCTU | |
Accessioni | P9WMW3Primary (citable) accession number: P9WMW3 Secondary accession number(s): L0TCZ9, P64261, Q50640 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 16, 2014 |
Last sequence update: | April 16, 2014 | |
Last modified: | October 16, 2019 | |
This is version 30 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Complete proteome, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - Mycobacterium tuberculosis strains ATCC 25618 / H37Rv and CDC 1551 / Oshkosh
Mycobacterium tuberculosis strains ATCC 25618 / H37Rv and CDC 1551 / Oshkosh: entries and gene names