UniProtKB - P9WMW3 (Y2581_MYCTU)
Protein
Uncharacterized protein Rv2581c
Gene
Rv2581c
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Functioni
Cofactori
Zn2+By similarityNote: Binds 2 Zn2+ ions per subunit.By similarity
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 57 | Zinc 1; via tele nitrogenBy similarity | 1 | |
Metal bindingi | 59 | Zinc 1; via pros nitrogenBy similarity | 1 | |
Metal bindingi | 61 | Zinc 2By similarity | 1 | |
Metal bindingi | 62 | Zinc 2; via tele nitrogenBy similarity | 1 | |
Metal bindingi | 138 | Zinc 1; via tele nitrogenBy similarity | 1 | |
Metal bindingi | 162 | Zinc 1By similarity | 1 | |
Metal bindingi | 162 | Zinc 2By similarity | 1 | |
Metal bindingi | 203 | Zinc 2; via tele nitrogenBy similarity | 1 |
GO - Molecular functioni
- hydrolase activity Source: UniProtKB-KW
- metal ion binding Source: UniProtKB-KW
Keywordsi
Molecular function | Hydrolase |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Ordered Locus Names:Rv2581c ORF Names:MTCY227.20 |
Organismi | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Taxonomic identifieri | 83332 [NCBI] |
Taxonomic lineagei | Bacteria › Actinobacteria › Corynebacteriales › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex › |
Proteomesi |
|
Organism-specific databases
TubercuListi | Rv2581c |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000192361 | 1 – 224 | Uncharacterized protein Rv2581cAdd BLAST | 224 |
Proteomic databases
PaxDbi | P9WMW3 |
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
eggNOGi | COG0491, Bacteria |
OMAi | GAWGTNC |
PhylomeDBi | P9WMW3 |
Family and domain databases
Gene3Di | 3.60.15.10, 1 hit |
InterProi | View protein in InterPro IPR001279, Metallo-B-lactamas IPR036866, RibonucZ/Hydroxyglut_hydro |
Pfami | View protein in Pfam PF00753, Lactamase_B, 1 hit |
SMARTi | View protein in SMART SM00849, Lactamase_B, 1 hit |
SUPFAMi | SSF56281, SSF56281, 1 hit |
i Sequence
Sequence statusi: Complete.
P9WMW3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLITGFPAGL LACNCYVLAE RPGTDAVIVD PGQGAMGTLR RILDKNRLTP
60 70 80 90 100
AAVLLTHGHI DHIWSAQKVS DTFGCPTYVH PADRFMLTDP IYGLGPRIAQ
110 120 130 140 150
LVAGAFFREP KQVVELDRDG DKIDLGGISV NIDHTPGHTR GSVVFRVLQA
160 170 180 190 200
TNNDKDIVFT GDTLFERAIG RTDLAGGSGR DLLRSIVDKL LVLDDSTVVL
210 220
PGHGNSTTIG AERRFNPFLE GLSR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL123456 Genomic DNA Translation: CCP45377.1 |
PIRi | D70725 |
RefSeqi | NP_217097.1, NC_000962.3 WP_003413366.1, NZ_NVQJ01000023.1 |
Genome annotation databases
EnsemblBacteriai | CCP45377; CCP45377; Rv2581c |
GeneIDi | 45426583 888217 |
KEGGi | mtu:Rv2581c |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL123456 Genomic DNA Translation: CCP45377.1 |
PIRi | D70725 |
RefSeqi | NP_217097.1, NC_000962.3 WP_003413366.1, NZ_NVQJ01000023.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 83332.Rv2581c |
Proteomic databases
PaxDbi | P9WMW3 |
Genome annotation databases
EnsemblBacteriai | CCP45377; CCP45377; Rv2581c |
GeneIDi | 45426583 888217 |
KEGGi | mtu:Rv2581c |
Organism-specific databases
TubercuListi | Rv2581c |
Phylogenomic databases
eggNOGi | COG0491, Bacteria |
OMAi | GAWGTNC |
PhylomeDBi | P9WMW3 |
Family and domain databases
Gene3Di | 3.60.15.10, 1 hit |
InterProi | View protein in InterPro IPR001279, Metallo-B-lactamas IPR036866, RibonucZ/Hydroxyglut_hydro |
Pfami | View protein in Pfam PF00753, Lactamase_B, 1 hit |
SMARTi | View protein in SMART SM00849, Lactamase_B, 1 hit |
SUPFAMi | SSF56281, SSF56281, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Y2581_MYCTU | |
Accessioni | P9WMW3Primary (citable) accession number: P9WMW3 Secondary accession number(s): L0TCZ9, P64261, Q50640 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 16, 2014 |
Last sequence update: | April 16, 2014 | |
Last modified: | February 10, 2021 | |
This is version 35 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families