UniProtKB - P9WK33 (Y488_MYCTU)
Protein
Putative amino-acid transporter Rv0488
Gene
Rv0488
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Functioni
GO - Molecular functioni
- arginine transmembrane transporter activity Source: GO_Central
GO - Biological processi
- L-arginine transport Source: GO_Central
Keywordsi
Biological process | Amino-acid transport, Transport |
Enzyme and pathway databases
BioCyci | MTBH37RV:G185E-4617-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Putative amino-acid transporter Rv0488 |
Gene namesi | Ordered Locus Names:Rv0488 ORF Names:MTCY20G9.14 |
Organismi | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Taxonomic identifieri | 83332 [NCBI] |
Taxonomic lineagei | Bacteria › Actinobacteria › Corynebacteriales › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex › |
Proteomesi |
|
Organism-specific databases
TubercuListi | Rv0488 |
Subcellular locationi
- Cell membrane Curated; Multi-pass membrane protein Curated
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 25 – 45 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 57 – 77 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 104 – 124 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 133 – 153 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 169 – 189 | HelicalSequence analysisAdd BLAST | 21 |
GO - Cellular componenti
- integral component of membrane Source: UniProtKB-KW
- plasma membrane Source: GO_Central
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000103692 | 1 – 201 | Putative amino-acid transporter Rv0488Add BLAST | 201 |
Proteomic databases
PaxDbi | P9WK33 |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG4108ZUB Bacteria COG1279 LUCA |
KOi | K06895 |
OMAi | HWWSAGL |
PhylomeDBi | P9WK33 |
Family and domain databases
InterProi | View protein in InterPro IPR001123 LeuE-type IPR004777 Lys/arg_exporter |
PANTHERi | PTHR30086 PTHR30086, 1 hit |
Pfami | View protein in Pfam PF01810 LysE, 1 hit |
TIGRFAMsi | TIGR00948 2a75, 1 hit |
i Sequence
Sequence statusi: Complete.
P9WK33-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MMTLKVAIGP QNAFVLRQGI RREYVLVIVA LCGIADGALI AAGVGGFAAL
60 70 80 90 100
IHAHPNMTLV ARFGGAAFLI GYALLAARNA WRPSGLVPSE SGPAALIGVV
110 120 130 140 150
QMCLVVTFLN PHVYLDTVVL IGALANEESD LRWFFGAGAW AASVVWFAVL
160 170 180 190 200
GFSAGRLQPF FATPAAWRIL DALVAVTMIG VAVVVLVTSP SVPTANVALI
I
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL123456 Genomic DNA Translation: CCP43222.1 |
PIRi | C70744 |
RefSeqi | NP_215002.1, NC_000962.3 WP_003402377.1, NZ_NVQJ01000002.1 |
Genome annotation databases
EnsemblBacteriai | CCP43222; CCP43222; Rv0488 |
GeneIDi | 887171 |
KEGGi | mtu:Rv0488 mtv:RVBD_0488 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL123456 Genomic DNA Translation: CCP43222.1 |
PIRi | C70744 |
RefSeqi | NP_215002.1, NC_000962.3 WP_003402377.1, NZ_NVQJ01000002.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 83332.Rv0488 |
Proteomic databases
PaxDbi | P9WK33 |
Genome annotation databases
EnsemblBacteriai | CCP43222; CCP43222; Rv0488 |
GeneIDi | 887171 |
KEGGi | mtu:Rv0488 mtv:RVBD_0488 |
Organism-specific databases
TubercuListi | Rv0488 |
Phylogenomic databases
eggNOGi | ENOG4108ZUB Bacteria COG1279 LUCA |
KOi | K06895 |
OMAi | HWWSAGL |
PhylomeDBi | P9WK33 |
Enzyme and pathway databases
BioCyci | MTBH37RV:G185E-4617-MONOMER |
Family and domain databases
InterProi | View protein in InterPro IPR001123 LeuE-type IPR004777 Lys/arg_exporter |
PANTHERi | PTHR30086 PTHR30086, 1 hit |
Pfami | View protein in Pfam PF01810 LysE, 1 hit |
TIGRFAMsi | TIGR00948 2a75, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Y488_MYCTU | |
Accessioni | P9WK33Primary (citable) accession number: P9WK33 Secondary accession number(s): L0T6U2, P64711, Q11154 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 16, 2014 |
Last sequence update: | April 16, 2014 | |
Last modified: | May 8, 2019 | |
This is version 24 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Complete proteome, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - Mycobacterium tuberculosis strains ATCC 25618 / H37Rv and CDC 1551 / Oshkosh
Mycobacterium tuberculosis strains ATCC 25618 / H37Rv and CDC 1551 / Oshkosh: entries and gene names