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Protein

Hydrolase Rv0480c

Gene

Rv0480c

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei40Proton acceptorPROSITE-ProRule annotation1
Active sitei110Proton donorPROSITE-ProRule annotation1
Active sitei146NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Hydrolase Rv0480c (EC:3.5.-.-)
Gene namesi
Ordered Locus Names:Rv0480c
ORF Names:MTCY20G9.06c
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001584 Componenti: Chromosome

Organism-specific databases

TubercuListiRv0480c

Subcellular locationi

GO - Cellular componenti

  • cell wall Source: MTBBASE

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002132611 – 280Hydrolase Rv0480cAdd BLAST280

Proteomic databases

PaxDbiP9WJ01

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv0480c

Structurei

3D structure databases

ProteinModelPortaliP9WJ01
SMRiP9WJ01
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 251CN hydrolasePROSITE-ProRule annotationAdd BLAST251

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi132 – 141Val-rich10

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4107VJP Bacteria
COG0388 LUCA
KOiK11206
PhylomeDBiP9WJ01

Family and domain databases

Gene3Di3.60.110.10, 1 hit
InterProiView protein in InterPro
IPR003010 C-N_Hydrolase
IPR036526 C-N_Hydrolase_sf
IPR001110 UPF0012_CS
PfamiView protein in Pfam
PF00795 CN_hydrolase, 1 hit
SUPFAMiSSF56317 SSF56317, 1 hit
PROSITEiView protein in PROSITE
PS50263 CN_HYDROLASE, 1 hit
PS01227 UPF0012, 1 hit

Sequencei

Sequence statusi: Complete.

P9WJ01-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRIALAQIRS GTDPAANLQL VGKYAGEAAT AGAQLVVFPE ATMCRLGVPL
60 70 80 90 100
RQVAEPVDGP WANGVRRIAT EAGITVIAGM FTPTGDGRVT NTLIAAGPGT
110 120 130 140 150
PNQPDAHYHK IHLYDAFGFT ESRTVAPGRE PVVVVVDGVR VGLTVCYDIR
160 170 180 190 200
FPALYTELAR RGAQLIAVCA SWGSGPGKLE QWTLLARARA LDSMSYVAAA
210 220 230 240 250
GQADPGDART GVGASSAAPT GVGGSLVASP LGEVVVSAGT QPQLLVADID
260 270 280
VDNVAAARDR IAVLRNQTDF VQIDKAQSRG
Length:280
Mass (Da):28,995
Last modified:April 16, 2014 - v1
Checksum:i5A63EF070B04A443
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL123456 Genomic DNA Translation: CCP43214.1
PIRiC70743
RefSeqiNP_214994.2, NC_000962.3
WP_003402350.1, NZ_KK339370.1

Genome annotation databases

EnsemblBacteriaiCCP43214; CCP43214; Rv0480c
GeneIDi887163
KEGGimtu:Rv0480c

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL123456 Genomic DNA Translation: CCP43214.1
PIRiC70743
RefSeqiNP_214994.2, NC_000962.3
WP_003402350.1, NZ_KK339370.1

3D structure databases

ProteinModelPortaliP9WJ01
SMRiP9WJ01
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi83332.Rv0480c

Proteomic databases

PaxDbiP9WJ01

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCCP43214; CCP43214; Rv0480c
GeneIDi887163
KEGGimtu:Rv0480c

Organism-specific databases

TubercuListiRv0480c

Phylogenomic databases

eggNOGiENOG4107VJP Bacteria
COG0388 LUCA
KOiK11206
PhylomeDBiP9WJ01

Family and domain databases

Gene3Di3.60.110.10, 1 hit
InterProiView protein in InterPro
IPR003010 C-N_Hydrolase
IPR036526 C-N_Hydrolase_sf
IPR001110 UPF0012_CS
PfamiView protein in Pfam
PF00795 CN_hydrolase, 1 hit
SUPFAMiSSF56317 SSF56317, 1 hit
PROSITEiView protein in PROSITE
PS50263 CN_HYDROLASE, 1 hit
PS01227 UPF0012, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiY480_MYCTU
AccessioniPrimary (citable) accession number: P9WJ01
Secondary accession number(s): L0T5H5, Q11146
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 16, 2014
Last sequence update: April 16, 2014
Last modified: March 28, 2018
This is version 20 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Mycobacterium tuberculosis strains ATCC 25618 / H37Rv and CDC 1551 / Oshkosh
    Mycobacterium tuberculosis strains ATCC 25618 / H37Rv and CDC 1551 / Oshkosh: entries and gene names
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