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UniProtKB - P9WIY7 (Y2565_MYCTU)
Protein
Uncharacterized NTE family protein Rv2565
Gene
Rv2565
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 342 | NucleophilePROSITE-ProRule annotation | 1 | |
Active sitei | 456 | Proton acceptorPROSITE-ProRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 24 – 140 | cNMPAdd BLAST | 117 |
GO - Molecular functioni
- lysophospholipase activity Source: InterPro
GO - Biological processi
- lipid catabolic process Source: UniProtKB-KW
- phosphatidylcholine metabolic process Source: InterPro
Keywordsi
Molecular function | Hydrolase |
Biological process | Lipid degradation, Lipid metabolism |
Names & Taxonomyi
Protein namesi | Recommended name: Uncharacterized NTE family protein Rv2565 |
Gene namesi | Ordered Locus Names:Rv2565 ORF Names:MTCY9C4.03c |
Organismi | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Taxonomic identifieri | 83332 [NCBI] |
Taxonomic lineagei | Bacteria › Actinobacteria › Corynebacteriales › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex › |
Proteomesi |
|
Organism-specific databases
TubercuListi | Rv2565 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000172536 | 1 – 583 | Uncharacterized NTE family protein Rv2565Add BLAST | 583 |
Proteomic databases
PaxDbi | P9WIY7 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 309 – 469 | PNPLAPROSITE-ProRule annotationAdd BLAST | 161 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 313 – 318 | GXGXXGPROSITE-ProRule annotation | 6 | |
Motifi | 340 – 344 | GXSXGPROSITE-ProRule annotation | 5 | |
Motifi | 456 – 458 | DGA/GPROSITE-ProRule annotation | 3 |
Sequence similaritiesi
Belongs to the NTE family.Curated
Phylogenomic databases
eggNOGi | COG0664, Bacteria COG1752, Bacteria |
OMAi | AGEMAMI |
PhylomeDBi | P9WIY7 |
Family and domain databases
CDDi | cd00038, CAP_ED, 1 hit |
Gene3Di | 2.60.120.10, 1 hit |
InterProi | View protein in InterPro IPR016035, Acyl_Trfase/lysoPLipase IPR018490, cNMP-bd-like IPR000595, cNMP-bd_dom IPR001423, LysoPLipase_patatin_CS IPR002641, PNPLA_dom IPR014710, RmlC-like_jellyroll |
Pfami | View protein in Pfam PF00027, cNMP_binding, 1 hit PF01734, Patatin, 1 hit |
SMARTi | View protein in SMART SM00100, cNMP, 1 hit |
SUPFAMi | SSF51206, SSF51206, 1 hit SSF52151, SSF52151, 1 hit |
PROSITEi | View protein in PROSITE PS50042, CNMP_BINDING_3, 1 hit PS51635, PNPLA, 1 hit PS01237, UPF0028, 1 hit |
i Sequence
Sequence statusi: Complete.
P9WIY7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTTARRRPKR RGTDARTALR NVPILADIDD EQLERLATTV ERRHVPANQW
60 70 80 90 100
LFHAGEPADS IYIVDSGRFV AVAPEGHVFA EMASGDSIGD LGVIAGAARS
110 120 130 140 150
AGVRALRDGV VWRIAAETFT DMLEATPLLQ SAMLRAMARM LRQSRPAKTA
160 170 180 190 200
RRPRVIGVVS NGDTAAAPMV DAIATSLDSH GRTAVIAPPV ETTSAVQEYD
210 220 230 240 250
ELVEAFSETL DRAERSNDWV LVVADRGAGD LWRHYVSAQS DRLVVLVDQR
260 270 280 290 300
YPPDAVDSLA TQRPVHLITC LAEPDPSWWD RLAPVSHHPA NSDGFGALAR
310 320 330 340 350
RIAGRSLGLV MAGGGARGLA HFGVYQELTE AGVVIDRFGG TSSGAIASAA
360 370 380 390 400
FALGMDAGDA IAAAREFIAG SDPLGDYTIP ISALTRGGRV DRLVQGFFGN
410 420 430 440 450
TLIEHLPRGF FSVSADMITG DQIIHRRGSV SGAVRASISI PGLIPPVHNG
460 470 480 490 500
EQLLVDGGLL NNLPANVMCA DTDGEVICVD LRRTFVPSKG FGLLPPIVTP
510 520 530 540 550
PGLLRRLLTG TDNALPPLQE TLLRAFDLAA STANLRELPR VAAIIEPDVS
560 570 580
KIGVLNFKQI DAALEAGRMA ARAALQAQPD LVR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL123456 Genomic DNA Translation: CCP45361.1 |
PIRi | A70729 |
RefSeqi | NP_217081.1, NC_000962.3 WP_003901427.1, NZ_NVQJ01000023.1 |
Genome annotation databases
GeneIDi | 887288 |
KEGGi | mtu:Rv2565 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL123456 Genomic DNA Translation: CCP45361.1 |
PIRi | A70729 |
RefSeqi | NP_217081.1, NC_000962.3 WP_003901427.1, NZ_NVQJ01000023.1 |
3D structure databases
AlphaFoldDBi | P9WIY7 |
SMRi | P9WIY7 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 83332.Rv2565 |
Proteomic databases
PaxDbi | P9WIY7 |
Protocols and materials databases
DNASUi | 887288 |
Genome annotation databases
GeneIDi | 887288 |
KEGGi | mtu:Rv2565 |
Organism-specific databases
TubercuListi | Rv2565 |
Phylogenomic databases
eggNOGi | COG0664, Bacteria COG1752, Bacteria |
OMAi | AGEMAMI |
PhylomeDBi | P9WIY7 |
Family and domain databases
CDDi | cd00038, CAP_ED, 1 hit |
Gene3Di | 2.60.120.10, 1 hit |
InterProi | View protein in InterPro IPR016035, Acyl_Trfase/lysoPLipase IPR018490, cNMP-bd-like IPR000595, cNMP-bd_dom IPR001423, LysoPLipase_patatin_CS IPR002641, PNPLA_dom IPR014710, RmlC-like_jellyroll |
Pfami | View protein in Pfam PF00027, cNMP_binding, 1 hit PF01734, Patatin, 1 hit |
SMARTi | View protein in SMART SM00100, cNMP, 1 hit |
SUPFAMi | SSF51206, SSF51206, 1 hit SSF52151, SSF52151, 1 hit |
PROSITEi | View protein in PROSITE PS50042, CNMP_BINDING_3, 1 hit PS51635, PNPLA, 1 hit PS01237, UPF0028, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Y2565_MYCTU | |
Accessioni | P9WIY7Primary (citable) accession number: P9WIY7 Secondary accession number(s): L0TA62, P0A642, Q50733 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 16, 2014 |
Last sequence update: | April 16, 2014 | |
Last modified: | May 25, 2022 | |
This is version 37 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families