UniProtKB - P9WGY1 (RRF_MYCTU)
Protein
Ribosome-recycling factor
Gene
frr
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Functioni
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.UniRule annotation
GO - Molecular functioni
- ribosomal large subunit binding Source: GO_Central
- translation termination factor activity Source: MTBBASE
GO - Biological processi
- cytoplasmic translational termination Source: GO_Central
- translation Source: GO_Central
- translational termination Source: MTBBASE
Keywordsi
Biological process | Protein biosynthesis |
Names & Taxonomyi
Protein namesi | Recommended name: Ribosome-recycling factorUniRule annotationShort name: RRFUniRule annotation Alternative name(s): Ribosome-releasing factorUniRule annotation |
Gene namesi | Name:frrUniRule annotation Ordered Locus Names:Rv2882c ORF Names:MTCY274.13c |
Organismi | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Taxonomic identifieri | 83332 [NCBI] |
Taxonomic lineagei | Bacteria › Actinobacteria › Corynebacteriales › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex › |
Proteomesi |
|
Organism-specific databases
TubercuListi | Rv2882c |
Subcellular locationi
- Cytoplasm UniRule annotation
GO - Cellular componenti
- cell wall Source: MTBBASE
- cytoplasm Source: GO_Central
- cytosol Source: GOC
- plasma membrane Source: MTBBASE
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000167500 | 1 – 185 | Ribosome-recycling factorAdd BLAST | 185 |
Proteomic databases
PaxDbi | P9WGY1 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P9WGY1 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Sequence similaritiesi
Belongs to the RRF family.UniRule annotation
Phylogenomic databases
eggNOGi | COG0233, Bacteria |
OMAi | FNPMNNG |
PhylomeDBi | P9WGY1 |
Family and domain databases
CDDi | cd00520, RRF, 1 hit |
HAMAPi | MF_00040, RRF, 1 hit |
InterProi | View protein in InterPro IPR002661, Ribosome_recyc_fac IPR023584, Ribosome_recyc_fac_dom IPR036191, RRF_sf |
PANTHERi | PTHR20982, PTHR20982, 1 hit |
Pfami | View protein in Pfam PF01765, RRF, 1 hit |
SUPFAMi | SSF55194, SSF55194, 1 hit |
TIGRFAMsi | TIGR00496, frr, 1 hit |
i Sequence
Sequence statusi: Complete.
P9WGY1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MIDEALFDAE EKMEKAVAVA RDDLSTIRTG RANPGMFSRI TIDYYGAATP
60 70 80 90 100
ITQLASINVP EARLVVIKPY EANQLRAIET AIRNSDLGVN PTNDGALIRV
110 120 130 140 150
AVPQLTEERR RELVKQAKHK GEEAKVSVRN IRRKAMEELH RIRKEGEAGE
160 170 180
DEVGRAEKDL DKTTHQYVTQ IDELVKHKEG ELLEV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL123456 Genomic DNA Translation: CCP45684.1 |
PIRi | E70924 |
RefSeqi | NP_217398.1, NC_000962.3 WP_003414663.1, NZ_NVQJ01000006.1 |
Genome annotation databases
EnsemblBacteriai | CCP45684; CCP45684; Rv2882c |
GeneIDi | 23490877 887464 |
KEGGi | mtu:Rv2882c mtv:RVBD_2882c |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL123456 Genomic DNA Translation: CCP45684.1 |
PIRi | E70924 |
RefSeqi | NP_217398.1, NC_000962.3 WP_003414663.1, NZ_NVQJ01000006.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1WQF | X-ray | 2.65 | A | 1-185 | [»] | |
1WQG | X-ray | 2.15 | A | 1-185 | [»] | |
1WQH | X-ray | 2.90 | A | 1-185 | [»] | |
4KAW | X-ray | 2.50 | X | 1-185 | [»] | |
4KB2 | X-ray | 2.30 | A | 1-185 | [»] | |
4KB4 | X-ray | 2.25 | A | 1-185 | [»] | |
4KC6 | X-ray | 2.40 | A | 1-179 | [»] | |
4KDD | X-ray | 1.90 | A | 1-185 | [»] | |
SMRi | P9WGY1 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 83332.Rv2882c |
Proteomic databases
PaxDbi | P9WGY1 |
Genome annotation databases
EnsemblBacteriai | CCP45684; CCP45684; Rv2882c |
GeneIDi | 23490877 887464 |
KEGGi | mtu:Rv2882c mtv:RVBD_2882c |
Organism-specific databases
TubercuListi | Rv2882c |
Phylogenomic databases
eggNOGi | COG0233, Bacteria |
OMAi | FNPMNNG |
PhylomeDBi | P9WGY1 |
Family and domain databases
CDDi | cd00520, RRF, 1 hit |
HAMAPi | MF_00040, RRF, 1 hit |
InterProi | View protein in InterPro IPR002661, Ribosome_recyc_fac IPR023584, Ribosome_recyc_fac_dom IPR036191, RRF_sf |
PANTHERi | PTHR20982, PTHR20982, 1 hit |
Pfami | View protein in Pfam PF01765, RRF, 1 hit |
SUPFAMi | SSF55194, SSF55194, 1 hit |
TIGRFAMsi | TIGR00496, frr, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RRF_MYCTU | |
Accessioni | P9WGY1Primary (citable) accession number: P9WGY1 Secondary accession number(s): L0TCI6, P66734, Q10794 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 16, 2014 |
Last sequence update: | April 16, 2014 | |
Last modified: | December 2, 2020 | |
This is version 36 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families