UniProtKB - P9WGQ7 (Y1144_MYCTU)
Protein
Uncharacterized oxidoreductase Rv1144
Gene
Rv1144
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 143 | SubstrateBy similarity | 1 | |
Active sitei | 156 | Proton acceptorPROSITE-ProRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 7 – 32 | NADBy similarityAdd BLAST | 26 |
GO - Molecular functioni
- oxidoreductase activity Source: UniProtKB-KW
Keywordsi
Molecular function | Oxidoreductase |
Enzyme and pathway databases
BioCyci | MTBH37RV:G185E-5311-MONOMER |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Ordered Locus Names:Rv1144 |
Organismi | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Taxonomic identifieri | 83332 [NCBI] |
Taxonomic lineagei | Bacteria › Actinobacteria › Corynebacteriales › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex › |
Proteomesi |
|
Organism-specific databases
TubercuListi | Rv1144 |
Subcellular locationi
GO - Cellular componenti
- cell wall Source: MTBBASE
- plasma membrane Source: MTBBASE
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000415506 | 1 – 250 | Uncharacterized oxidoreductase Rv1144Add BLAST | 250 |
Proteomic databases
PaxDbi | P9WGQ7 |
PRIDEi | P9WGQ7 |
Family & Domainsi
Sequence similaritiesi
Belongs to the short-chain dehydrogenases/reductases (SDR) family.Curated
Phylogenomic databases
eggNOGi | ENOG4105EK9 Bacteria ENOG410XNNW LUCA |
OMAi | FRALVHC |
PhylomeDBi | P9WGQ7 |
Family and domain databases
InterProi | View protein in InterPro IPR036291 NAD(P)-bd_dom_sf IPR020904 Sc_DH/Rdtase_CS IPR002347 SDR_fam |
Pfami | View protein in Pfam PF00106 adh_short, 1 hit |
PRINTSi | PR00081 GDHRDH PR00080 SDRFAMILY |
SUPFAMi | SSF51735 SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00061 ADH_SHORT, 1 hit |
i Sequence
Sequence statusi: Complete.
P9WGQ7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKTKDAVAVV TGGASGLGLA TTKRLLDAGA QVVVVDLRGD DVVGGLGDRA
60 70 80 90 100
RFAQADVTDE AAVSNALELA DSLGPVRVVV NCAGTGNAIR VLSRDGVFPL
110 120 130 140 150
AAFRKIVDIN LVGTFNVLRL GAERIAKTEP IGEERGVIIN TASVAAFDGQ
160 170 180 190 200
IGQAAYSASK GGVVGMTLPI ARDLASKLIR VVTIAPGLFD TPLLASLPAE
210 220 230 240 250
AKASLGQQVP HPSRLGNPDE YGALVLHIIE NPMLNGEVIR LDGAIRMAPR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL123456 Genomic DNA Translation: CCP43899.1 |
PIRi | A70554 |
RefSeqi | NP_215660.1, NC_000962.3 WP_003405961.1, NZ_NVQJ01000021.1 |
Genome annotation databases
EnsemblBacteriai | CCP43899; CCP43899; Rv1144 |
GeneIDi | 885932 |
KEGGi | mtu:Rv1144 mtv:RVBD_1144 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL123456 Genomic DNA Translation: CCP43899.1 |
PIRi | A70554 |
RefSeqi | NP_215660.1, NC_000962.3 WP_003405961.1, NZ_NVQJ01000021.1 |
3D structure databases
SMRi | P9WGQ7 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 83332.Rv1144 |
Proteomic databases
PaxDbi | P9WGQ7 |
PRIDEi | P9WGQ7 |
Genome annotation databases
EnsemblBacteriai | CCP43899; CCP43899; Rv1144 |
GeneIDi | 885932 |
KEGGi | mtu:Rv1144 mtv:RVBD_1144 |
Organism-specific databases
TubercuListi | Rv1144 |
Phylogenomic databases
eggNOGi | ENOG4105EK9 Bacteria ENOG410XNNW LUCA |
OMAi | FRALVHC |
PhylomeDBi | P9WGQ7 |
Enzyme and pathway databases
BioCyci | MTBH37RV:G185E-5311-MONOMER |
Family and domain databases
InterProi | View protein in InterPro IPR036291 NAD(P)-bd_dom_sf IPR020904 Sc_DH/Rdtase_CS IPR002347 SDR_fam |
Pfami | View protein in Pfam PF00106 adh_short, 1 hit |
PRINTSi | PR00081 GDHRDH PR00080 SDRFAMILY |
SUPFAMi | SSF51735 SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00061 ADH_SHORT, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Y1144_MYCTU | |
Accessioni | P9WGQ7Primary (citable) accession number: P9WGQ7 Secondary accession number(s): L0T7F6, O06544, Q7D8R8 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 16, 2014 |
Last sequence update: | April 16, 2014 | |
Last modified: | October 16, 2019 | |
This is version 27 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Complete proteome, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - Mycobacterium tuberculosis strains ATCC 25618 / H37Rv and CDC 1551 / Oshkosh
Mycobacterium tuberculosis strains ATCC 25618 / H37Rv and CDC 1551 / Oshkosh: entries and gene names