UniProtKB - P9WGM3 (PDTAR_MYCTU)
Protein
Probable transcriptional regulatory protein pdtaR
Gene
pdtaR
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Functioni
Member of the two-component regulatory system pdtaR/pdtaS.1 Publication
GO - Molecular functioni
- anion binding Source: CAFA
- RNA binding Source: InterPro
GO - Biological processi
- phosphorelay signal transduction system Source: MTBBASE
- transcription antitermination Source: UniProtKB-KW
Keywordsi
Biological process | Transcription, Transcription antitermination, Transcription regulation, Two-component regulatory system |
Enzyme and pathway databases
BioCyci | MTBH37RV:G185E-5815-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Probable transcriptional regulatory protein pdtaR |
Gene namesi | Name:pdtaR Ordered Locus Names:Rv1626 |
Organismi | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Taxonomic identifieri | 83332 [NCBI] |
Taxonomic lineagei | Bacteria › Actinobacteria › Corynebacteriales › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex › |
Proteomesi |
|
Organism-specific databases
TubercuListi | Rv1626 |
Subcellular locationi
GO - Cellular componenti
- cell wall Source: MTBBASE
- plasma membrane Source: MTBBASE
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | RemovedCombined sources | |||
ChainiPRO_0000386597 | 2 – 205 | Probable transcriptional regulatory protein pdtaRAdd BLAST | 204 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 2 | N-acetylthreonineCombined sources | 1 | |
Modified residuei | 65 | 4-aspartylphosphatePROSITE-ProRule annotation | 1 |
Post-translational modificationi
Phosphorylated by pdtaS.1 Publication
Keywords - PTMi
Acetylation, PhosphoproteinProteomic databases
PaxDbi | P9WGM3 |
PTM databases
iPTMneti | P9WGM3 |
Interactioni
Subunit structurei
Monomer. Dimer; when bound to its cognate DNA (Potential).
CuratedProtein-protein interaction databases
STRINGi | 83332.Rv1626 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P9WGM3 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 15 – 129 | Response regulatoryPROSITE-ProRule annotationAdd BLAST | 115 | |
Domaini | 135 – 196 | ANTARPROSITE-ProRule annotationAdd BLAST | 62 |
Phylogenomic databases
eggNOGi | ENOG4105GJG Bacteria COG3707 LUCA |
KOi | K22010 |
OMAi | AAFRWIQ |
PhylomeDBi | P9WGM3 |
Family and domain databases
CDDi | cd00156 REC, 1 hit |
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR005561 ANTAR IPR011006 CheY-like_superfamily IPR008327 Sig_transdc_resp-reg_antiterm IPR001789 Sig_transdc_resp-reg_receiver IPR036388 WH-like_DNA-bd_sf |
Pfami | View protein in Pfam PF03861 ANTAR, 1 hit PF00072 Response_reg, 1 hit |
PIRSFi | PIRSF036382 RR_antiterm, 1 hit |
SMARTi | View protein in SMART SM01012 ANTAR, 1 hit SM00448 REC, 1 hit |
SUPFAMi | SSF52172 SSF52172, 1 hit |
PROSITEi | View protein in PROSITE PS50921 ANTAR, 1 hit PS50110 RESPONSE_REGULATORY, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P9WGM3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTGPTTDADA AVPRRVLIAE DEALIRMDLA EMLREEGYEI VGEAGDGQEA
60 70 80 90 100
VELAELHKPD LVIMDVKMPR RDGIDAASEI ASKRIAPIVV LTAFSQRDLV
110 120 130 140 150
ERARDAGAMA YLVKPFSISD LIPAIELAVS RFREITALEG EVATLSERLE
160 170 180 190 200
TRKLVERAKG LLQTKHGMTE PDAFKWIQRA AMDRRTTMKR VAEVVLETLG
TPKDT
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL123456 Genomic DNA Translation: CCP44390.1 |
PIRi | H70558 |
RefSeqi | NP_216142.1, NC_000962.3 WP_003408045.1, NZ_NVQJ01000016.1 |
Genome annotation databases
EnsemblBacteriai | CCP44390; CCP44390; Rv1626 |
GeneIDi | 885080 |
KEGGi | mtu:Rv1626 mtv:RVBD_1626 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL123456 Genomic DNA Translation: CCP44390.1 |
PIRi | H70558 |
RefSeqi | NP_216142.1, NC_000962.3 WP_003408045.1, NZ_NVQJ01000016.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1S8N | X-ray | 1.48 | A | 1-205 | [»] | |
1SD5 | X-ray | 1.68 | A | 1-205 | [»] | |
SMRi | P9WGM3 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 83332.Rv1626 |
PTM databases
iPTMneti | P9WGM3 |
Proteomic databases
PaxDbi | P9WGM3 |
Genome annotation databases
EnsemblBacteriai | CCP44390; CCP44390; Rv1626 |
GeneIDi | 885080 |
KEGGi | mtu:Rv1626 mtv:RVBD_1626 |
Organism-specific databases
TubercuListi | Rv1626 |
Phylogenomic databases
eggNOGi | ENOG4105GJG Bacteria COG3707 LUCA |
KOi | K22010 |
OMAi | AAFRWIQ |
PhylomeDBi | P9WGM3 |
Enzyme and pathway databases
BioCyci | MTBH37RV:G185E-5815-MONOMER |
Family and domain databases
CDDi | cd00156 REC, 1 hit |
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR005561 ANTAR IPR011006 CheY-like_superfamily IPR008327 Sig_transdc_resp-reg_antiterm IPR001789 Sig_transdc_resp-reg_receiver IPR036388 WH-like_DNA-bd_sf |
Pfami | View protein in Pfam PF03861 ANTAR, 1 hit PF00072 Response_reg, 1 hit |
PIRSFi | PIRSF036382 RR_antiterm, 1 hit |
SMARTi | View protein in SMART SM01012 ANTAR, 1 hit SM00448 REC, 1 hit |
SUPFAMi | SSF52172 SSF52172, 1 hit |
PROSITEi | View protein in PROSITE PS50921 ANTAR, 1 hit PS50110 RESPONSE_REGULATORY, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | PDTAR_MYCTU | |
Accessioni | P9WGM3Primary (citable) accession number: P9WGM3 Secondary accession number(s): L0T8T8, O06143, Q7D890 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 16, 2014 |
Last sequence update: | April 16, 2014 | |
Last modified: | October 16, 2019 | |
This is version 31 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Complete proteome, Reference proteomeDocuments
- Mycobacterium tuberculosis strains ATCC 25618 / H37Rv and CDC 1551 / Oshkosh
Mycobacterium tuberculosis strains ATCC 25618 / H37Rv and CDC 1551 / Oshkosh: entries and gene names - PDB cross-references
Index of Protein Data Bank (PDB) cross-references