UniProtKB - P99139 (MOEA_STAAN)
Protein
Molybdopterin molybdenumtransferase
Gene
moeA
Organism
Staphylococcus aureus (strain N315)
Status
Functioni
Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.By similarity
Catalytic activityi
- EC:2.10.1.1
Cofactori
Mg2+By similarityNote: Binds 1 Mg2+ ion per subunit.By similarity
: molybdopterin biosynthesis Pathwayi
This protein is involved in the pathway molybdopterin biosynthesis, which is part of Cofactor biosynthesis.View all proteins of this organism that are known to be involved in the pathway molybdopterin biosynthesis and in Cofactor biosynthesis.
GO - Molecular functioni
- metal ion binding Source: UniProtKB-KW
- molybdopterin molybdotransferase activity Source: UniProtKB-EC
GO - Biological processi
- molybdopterin cofactor biosynthetic process Source: InterPro
- Mo-molybdopterin cofactor biosynthetic process Source: UniProtKB-KW
Keywordsi
Molecular function | Transferase |
Biological process | Molybdenum cofactor biosynthesis |
Ligand | Magnesium, Metal-binding, Molybdenum |
Enzyme and pathway databases
BioCyci | SAUR158879:G1G21-2411-MONOMER |
UniPathwayi | UPA00344 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:moeA Ordered Locus Names:SA2068 |
Organismi | Staphylococcus aureus (strain N315) |
Taxonomic identifieri | 158879 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Bacillales › Staphylococcaceae › Staphylococcus › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000170996 | 1 – 419 | Molybdopterin molybdenumtransferaseAdd BLAST | 419 |
2D gel databases
SWISS-2DPAGEi | P99139 |
Family & Domainsi
Sequence similaritiesi
Belongs to the MoeA family.Curated
Phylogenomic databases
HOGENOMi | CLU_010186_7_1_9 |
OMAi | MTGAMVP |
Family and domain databases
CDDi | cd00887, MoeA, 1 hit |
Gene3Di | 2.40.340.10, 1 hit 3.40.980.10, 1 hit |
InterProi | View protein in InterPro IPR036425, MoaB/Mog-like_dom_sf IPR001453, MoaB/Mog_dom IPR038987, MoeA-like IPR005111, MoeA_C_domain_IV IPR036688, MoeA_C_domain_IV_sf IPR005110, MoeA_linker/N IPR036135, MoeA_linker/N_sf |
PANTHERi | PTHR10192, PTHR10192, 1 hit |
Pfami | View protein in Pfam PF00994, MoCF_biosynth, 1 hit PF03454, MoeA_C, 1 hit PF03453, MoeA_N, 1 hit |
SMARTi | View protein in SMART SM00852, MoCF_biosynth, 1 hit |
SUPFAMi | SSF53218, SSF53218, 1 hit SSF63867, SSF63867, 1 hit SSF63882, SSF63882, 1 hit |
TIGRFAMsi | TIGR00177, molyb_syn, 1 hit |
i Sequence
Sequence statusi: Complete.
P99139-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVVEKRNPIP VKEAIQRIVN QQSSMPAITV ALEKSLNHIL AEDIVATYDI
60 70 80 90 100
PRFDKSPYDG FAIRSVDSQG ASGQNRIEFK VIDHIGAGSV SDKLVGDHEA
110 120 130 140 150
VRIMTGAQIP NGADAVVMFE QTIELEDTFT IRKPFSKNEN ISLKGEETKT
160 170 180 190 200
GDVVLKKGQV INPGAIAVLA TYGYAEVKVI KQPSVAVIAT GSELLDVNDV
210 220 230 240 250
LEDGKIRNSN GPMIRALAEK LGLEVGIYKT QKDDLDSGIQ VVKEAMEKHD
260 270 280 290 300
IVITTGGVSV GDFDYLPEIY KAVKAEVLFN KVAMRPGSVT TVAFADGKYL
310 320 330 340 350
FGLSGNPSAC FTGFELFVKP AVKHMCGALE VFPQIIKATL MEDFTKANPF
360 370 380 390 400
TRFIRAKATL TSAGATVVPS GFNKSGAVVA IAHANCMVML PGGSRGFKAG
410
HTVDIILTES DAAEEELLL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BA000018 Genomic DNA Translation: BAB43365.1 |
PIRi | D90025 |
RefSeqi | WP_000259717.1, NC_002745.2 |
Genome annotation databases
EnsemblBacteriai | BAB43365; BAB43365; BAB43365 |
KEGGi | sau:SA2068 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BA000018 Genomic DNA Translation: BAB43365.1 |
PIRi | D90025 |
RefSeqi | WP_000259717.1, NC_002745.2 |
3D structure databases
SMRi | P99139 |
ModBasei | Search... |
2D gel databases
SWISS-2DPAGEi | P99139 |
Genome annotation databases
EnsemblBacteriai | BAB43365; BAB43365; BAB43365 |
KEGGi | sau:SA2068 |
Phylogenomic databases
HOGENOMi | CLU_010186_7_1_9 |
OMAi | MTGAMVP |
Enzyme and pathway databases
UniPathwayi | UPA00344 |
BioCyci | SAUR158879:G1G21-2411-MONOMER |
Family and domain databases
CDDi | cd00887, MoeA, 1 hit |
Gene3Di | 2.40.340.10, 1 hit 3.40.980.10, 1 hit |
InterProi | View protein in InterPro IPR036425, MoaB/Mog-like_dom_sf IPR001453, MoaB/Mog_dom IPR038987, MoeA-like IPR005111, MoeA_C_domain_IV IPR036688, MoeA_C_domain_IV_sf IPR005110, MoeA_linker/N IPR036135, MoeA_linker/N_sf |
PANTHERi | PTHR10192, PTHR10192, 1 hit |
Pfami | View protein in Pfam PF00994, MoCF_biosynth, 1 hit PF03454, MoeA_C, 1 hit PF03453, MoeA_N, 1 hit |
SMARTi | View protein in SMART SM00852, MoCF_biosynth, 1 hit |
SUPFAMi | SSF53218, SSF53218, 1 hit SSF63867, SSF63867, 1 hit SSF63882, SSF63882, 1 hit |
TIGRFAMsi | TIGR00177, molyb_syn, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | MOEA_STAAN | |
Accessioni | P99139Primary (citable) accession number: P99139 Secondary accession number(s): Q99RZ9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 11, 2004 |
Last sequence update: | October 11, 2004 | |
Last modified: | December 2, 2020 | |
This is version 87 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Documents
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families