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Entry version 142 (08 May 2019)
Sequence version 2 (02 Aug 2005)
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Protein

Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog

Gene

Arvcf

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in protein-protein interactions at adherens junctions.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • cadherin binding Source: GO_Central

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell adhesion

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Arvcf
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

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MGIi
MGI:109620 Arvcf

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000642951 – 962Armadillo repeat protein deleted in velo-cardio-facial syndrome homologAdd BLAST962

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei103PhosphothreonineBy similarity1
Modified residuei105PhosphothreonineBy similarity1
Modified residuei171Omega-N-methylarginineCombined sources1
Modified residuei269PhosphoserineCombined sources1
Modified residuei334PhosphoserineCombined sources1
Modified residuei337PhosphoserineCombined sources1
Modified residuei345PhosphoserineBy similarity1
Modified residuei347PhosphoserineBy similarity1
Modified residuei607PhosphoserineBy similarity1
Modified residuei643PhosphothreonineCombined sources1
Modified residuei864PhosphoserineBy similarity1
Modified residuei871PhosphoserineBy similarity1
Modified residuei872PhosphothreonineBy similarity1

Keywords - PTMi

Methylation, Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P98203

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P98203

PeptideAtlas

More...
PeptideAtlasi
P98203

PRoteomics IDEntifications database

More...
PRIDEi
P98203

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P98203

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P98203

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
P98203

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000000325 Expressed in 257 organ(s), highest expression level in epithelium of lens

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
P98203 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
P98203 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts (via the extreme C-terminus) with FRMPD2 (via the PDZ 2 domain).

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
198214, 5 interactors

Protein interaction database and analysis system

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IntActi
P98203, 2 interactors

Molecular INTeraction database

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MINTi
P98203

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000111276

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P98203

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati350 – 389ARM 1Add BLAST40
Repeati392 – 431ARM 2Add BLAST40
Repeati435 – 469ARM 3Add BLAST35
Repeati470 – 510ARM 4Add BLAST41
Repeati528 – 567ARM 5Add BLAST40
Repeati577 – 623ARM 6Add BLAST47
Repeati647 – 687ARM 7Add BLAST41
Repeati700 – 739ARM 8Add BLAST40
Repeati740 – 782ARM 9Add BLAST43
Repeati783 – 827ARM 10Add BLAST45

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili11 – 46Sequence analysisAdd BLAST36

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi608 – 624Nuclear localization signalSequence analysisAdd BLAST17

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the beta-catenin family.Curated

Keywords - Domaini

Coiled coil, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1048 Eukaryota
ENOG410Y21Q LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157027

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P98203

Identification of Orthologs from Complete Genome Data

More...
OMAi
WSTYIRA

Database of Orthologous Groups

More...
OrthoDBi
233858at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P98203

TreeFam database of animal gene trees

More...
TreeFami
TF321877

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024 ARM-type_fold
IPR000225 Armadillo
IPR028444 ARVCF
IPR028435 Plakophilin/d_Catenin

The PANTHER Classification System

More...
PANTHERi
PTHR10372 PTHR10372, 1 hit
PTHR10372:SF5 PTHR10372:SF5, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00514 Arm, 4 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00185 ARM, 6 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50176 ARM_REPEAT, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: P98203-1) [UniParc]FASTAAdd to basket
Also known as: A1

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEDCNVHSAA SILASVKEQE ARFERLTRAL EQERRHVALQ LERAQQPGMS
60 70 80 90 100
SGGMVGSGQP LPMAWQQLVL QEQSPGSQAS LATMPEAPEV LEETVTVEED
110 120 130 140 150
PGTPTSHVSI VTSEDGTTRR TETKVTKTVK TVTTRTVRQV PLGPDGLPLL
160 170 180 190 200
DGGPPLGSFA DGPLDRHYLL RGGGGPAATL SRTYHSSGGG FPDGPESRDI
210 220 230 240 250
PSYGSLSRGL GVRPPRTGLL GPGPGDGCFT LPGRREAFPM GSESGPPSGR
260 270 280 290 300
SLPEHFQAEP YGLEDDTRSL AADDEGGPDL EPDYSTATRR RPEYGRGLRA
310 320 330 340 350
RAFEDTADDA GELIEERPPF PAATAPLAQP ERGSLGSLDR VVRRSPSVDS
360 370 380 390 400
TRKEPRWRDP ELPEVLAMLR HPVDPVKANA AAYLQHLCFE NEGIKRRVRQ
410 420 430 440 450
LRGLPLLVAL LDHPRAEVRR RACGALRNLS YGRDTDNKAA IRDCGGVPAL
460 470 480 490 500
VRLLRAARDN EVRELVTGTL WNLSSYEPLK MVIIDHGLQT LTHEVIVPHS
510 520 530 540 550
GWEREPNEDS KPRDAEWTTV FKNTSGCLRN VSSDGAEARR RLRECEGLVD
560 570 580 590 600
ALLHALQSAV GRKDTDNKSV ENCVCIMRNL SYHVHKEVPG ADRYQEAEPG
610 620 630 640 650
IPGSTTSQRR RKDDASCFGG KKAKEEWFHQ GKKDAEMDRN FDTLDLPKRT
660 670 680 690 700
EAAKGFELLY QPEVVRLYLS LLTESRNFNT LEAAAGALQN LSAGNWTWAT
710 720 730 740 750
YIRATVRKER GLPVLVELLQ SETDKVVRAV AIALRNLSLD QRNKDLIGSY
760 770 780 790 800
AMTELVRNVR NAQAPAHPSA HLEEDTVVAV LNTIHEIVSD SLDNARSLLQ
810 820 830 840 850
ARGVPALVAL VASSQSVREA KAASHVLQTV WSYKELRGAL QRDGWTKSRF
860 870 880 890 900
QSASTAKGPK GTPSSGGFDD STLPLVDKSL DGEKSNTRDV IPMDTLGPDG
910 920 930 940 950
YATVDRRERR TLGSDSTGDT SEKELLRPDP GRKAPPPGPS RPSVRLVDAV
960
GDTKPQPVDS WV
Length:962
Mass (Da):105,066
Last modified:August 2, 2005 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8F43E9DC34709406
GO
Isoform 2 (identifier: P98203-2) [UniParc]FASTAAdd to basket
Also known as: A2

The sequence of this isoform differs from the canonical sequence as follows:
     625-630: Missing.

Show »
Length:956
Mass (Da):104,209
Checksum:i11BA42849409059E
GO
Isoform 4 (identifier: P98203-4) [UniParc]FASTAAdd to basket
Also known as: B2

The sequence of this isoform differs from the canonical sequence as follows:
     1-70: MEDCNVHSAA...LPMAWQQLVL → MPAELR
     625-630: Missing.

Show »
Length:892
Mass (Da):97,165
Checksum:i937AA47D6064ED90
GO
Isoform 5 (identifier: P98203-5) [UniParc]FASTAAdd to basket
Also known as: B1

The sequence of this isoform differs from the canonical sequence as follows:
     1-70: MEDCNVHSAA...LPMAWQQLVL → MPAELR

Show »
Length:898
Mass (Da):98,022
Checksum:i0876464C4BF836C6
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A338P7H0A0A338P7H0_MOUSE
Armadillo repeat protein deleted in...
Arvcf
131Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RI19D6RI19_MOUSE
Armadillo repeat protein deleted in...
Arvcf
142Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AJ243418 differs from that shown. Aberrant splicing.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti72E → G in AAH56980 (PubMed:15489334).Curated1
Sequence conflicti372P → T in BAC39302 (PubMed:16141072).Curated1
Sequence conflicti504R → L in AAK64214 (Ref. 1) Curated1
Sequence conflicti504R → L in AAK64215 (Ref. 1) Curated1
Sequence conflicti504R → L in AAK64216 (Ref. 1) Curated1
Sequence conflicti504R → L in AAK64217 (Ref. 1) Curated1
Sequence conflicti560V → E in BAC39302 (PubMed:16141072).Curated1
Sequence conflicti761N → K in BAC39302 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0149221 – 70MEDCN…QQLVL → MPAELR in isoform 4 and isoform 5. 2 PublicationsAdd BLAST70
Alternative sequenceiVSP_014923625 – 630Missing in isoform 2 and isoform 4. 3 Publications6

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF286212 mRNA Translation: AAK64214.1
AF286213 mRNA Translation: AAK64215.1
AF286214 mRNA Translation: AAK64216.1
AF286215 mRNA Translation: AAK64217.1
AK044982 mRNA Translation: BAC32169.1
AK051627 mRNA Translation: BAC34696.1
AK084886 mRNA Translation: BAC39302.1
BC056980 mRNA Translation: AAH56980.1
AJ243418 mRNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS28020.1 [P98203-1]
CCDS70693.1 [P98203-2]
CCDS70694.1 [P98203-4]

NCBI Reference Sequences

More...
RefSeqi
NP_001258957.1, NM_001272028.1 [P98203-1]
NP_001258958.1, NM_001272029.1 [P98203-2]
NP_001258959.1, NM_001272030.1 [P98203-2]
NP_001258960.1, NM_001272031.1 [P98203-5]
NP_001258961.1, NM_001272032.1 [P98203-4]
NP_258435.2, NM_033474.3 [P98203-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000090103; ENSMUSP00000087562; ENSMUSG00000000325 [P98203-1]
ENSMUST00000115610; ENSMUSP00000111273; ENSMUSG00000000325 [P98203-4]
ENSMUST00000115612; ENSMUSP00000111275; ENSMUSG00000000325 [P98203-2]
ENSMUST00000115613; ENSMUSP00000111276; ENSMUSG00000000325 [P98203-1]
ENSMUST00000115614; ENSMUSP00000111278; ENSMUSG00000000325 [P98203-2]
ENSMUST00000150253; ENSMUSP00000118505; ENSMUSG00000000325 [P98203-4]
ENSMUST00000184717; ENSMUSP00000139078; ENSMUSG00000098615 [P98203-1]
ENSMUST00000230969; ENSMUSP00000155564; ENSMUSG00000098615 [P98203-1]
ENSMUST00000232025; ENSMUSP00000155883; ENSMUSG00000000325 [P98203-5]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
11877

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:11877

UCSC genome browser

More...
UCSCi
uc007ynl.2 mouse [P98203-1]
uc007ynm.2 mouse [P98203-2]
uc007ynq.2 mouse [P98203-5]
uc007yns.2 mouse [P98203-4]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF286212 mRNA Translation: AAK64214.1
AF286213 mRNA Translation: AAK64215.1
AF286214 mRNA Translation: AAK64216.1
AF286215 mRNA Translation: AAK64217.1
AK044982 mRNA Translation: BAC32169.1
AK051627 mRNA Translation: BAC34696.1
AK084886 mRNA Translation: BAC39302.1
BC056980 mRNA Translation: AAH56980.1
AJ243418 mRNA No translation available.
CCDSiCCDS28020.1 [P98203-1]
CCDS70693.1 [P98203-2]
CCDS70694.1 [P98203-4]
RefSeqiNP_001258957.1, NM_001272028.1 [P98203-1]
NP_001258958.1, NM_001272029.1 [P98203-2]
NP_001258959.1, NM_001272030.1 [P98203-2]
NP_001258960.1, NM_001272031.1 [P98203-5]
NP_001258961.1, NM_001272032.1 [P98203-4]
NP_258435.2, NM_033474.3 [P98203-1]

3D structure databases

SMRiP98203
ModBaseiSearch...

Protein-protein interaction databases

BioGridi198214, 5 interactors
IntActiP98203, 2 interactors
MINTiP98203
STRINGi10090.ENSMUSP00000111276

PTM databases

iPTMnetiP98203
PhosphoSitePlusiP98203
SwissPalmiP98203

Proteomic databases

MaxQBiP98203
PaxDbiP98203
PeptideAtlasiP98203
PRIDEiP98203

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000090103; ENSMUSP00000087562; ENSMUSG00000000325 [P98203-1]
ENSMUST00000115610; ENSMUSP00000111273; ENSMUSG00000000325 [P98203-4]
ENSMUST00000115612; ENSMUSP00000111275; ENSMUSG00000000325 [P98203-2]
ENSMUST00000115613; ENSMUSP00000111276; ENSMUSG00000000325 [P98203-1]
ENSMUST00000115614; ENSMUSP00000111278; ENSMUSG00000000325 [P98203-2]
ENSMUST00000150253; ENSMUSP00000118505; ENSMUSG00000000325 [P98203-4]
ENSMUST00000184717; ENSMUSP00000139078; ENSMUSG00000098615 [P98203-1]
ENSMUST00000230969; ENSMUSP00000155564; ENSMUSG00000098615 [P98203-1]
ENSMUST00000232025; ENSMUSP00000155883; ENSMUSG00000000325 [P98203-5]
GeneIDi11877
KEGGimmu:11877
UCSCiuc007ynl.2 mouse [P98203-1]
uc007ynm.2 mouse [P98203-2]
uc007ynq.2 mouse [P98203-5]
uc007yns.2 mouse [P98203-4]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
421
MGIiMGI:109620 Arvcf

Phylogenomic databases

eggNOGiKOG1048 Eukaryota
ENOG410Y21Q LUCA
GeneTreeiENSGT00940000157027
InParanoidiP98203
OMAiWSTYIRA
OrthoDBi233858at2759
PhylomeDBiP98203
TreeFamiTF321877

Miscellaneous databases

Protein Ontology

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PROi
PR:P98203

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000000325 Expressed in 257 organ(s), highest expression level in epithelium of lens
ExpressionAtlasiP98203 baseline and differential
GenevisibleiP98203 MM

Family and domain databases

InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR000225 Armadillo
IPR028444 ARVCF
IPR028435 Plakophilin/d_Catenin
PANTHERiPTHR10372 PTHR10372, 1 hit
PTHR10372:SF5 PTHR10372:SF5, 1 hit
PfamiView protein in Pfam
PF00514 Arm, 4 hits
SMARTiView protein in SMART
SM00185 ARM, 6 hits
SUPFAMiSSF48371 SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS50176 ARM_REPEAT, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiARVC_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P98203
Secondary accession number(s): Q6PGJ6
, Q8BQ36, Q8BRF2, Q8C3U7, Q924L2, Q924L3, Q924L4, Q924L5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: August 2, 2005
Last modified: May 8, 2019
This is version 142 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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