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Protein

Protein FAM3A

Gene

FAM3A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May act as a defensin against invading fungal microorganisms.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein FAM3A
Alternative name(s):
Cytokine-like protein 2-19
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FAM3A
Synonyms:2-19, 2.19
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000071889.16

Human Gene Nomenclature Database

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HGNCi
HGNC:13749 FAM3A

Online Mendelian Inheritance in Man (OMIM)

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MIMi
300492 gene

neXtProt; the human protein knowledge platform

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neXtProti
NX_P98173

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

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OpenTargetsi
ENSG00000071889

The Pharmacogenetics and Pharmacogenomics Knowledge Base

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PharmGKBi
PA38366

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

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BioMutai
FAM3A

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 33Sequence analysisAdd BLAST33
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000000874834 – 230Protein FAM3AAdd BLAST197

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi59 ↔ 87By similarity
Disulfide bondi65 ↔ 222By similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
P98173

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
P98173

MaxQB - The MaxQuant DataBase

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MaxQBi
P98173

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
P98173

PeptideAtlas

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PeptideAtlasi
P98173

PRoteomics IDEntifications database

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PRIDEi
P98173

ProteomicsDB human proteome resource

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ProteomicsDBi
57807
57808 [P98173-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

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iPTMneti
P98173

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

In similar amounts in testis, pancreas, adrenal, placenta, brain, fetal brain, liver, kidney, skeletal muscle and heart.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000071889 Expressed in 209 organ(s), highest expression level in lower esophagus mucosa

CleanEx database of gene expression profiles

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CleanExi
HS_FAM3A

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
P98173 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
P98173 HS

Organism-specific databases

Human Protein Atlas

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HPAi
CAB025016
HPA056991

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
121898, 13 interactors

Protein interaction database and analysis system

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IntActi
P98173, 3 interactors

Molecular INTeraction database

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MINTi
P98173

STRING: functional protein association networks

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STRINGi
9606.ENSP00000352955

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
P98173

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P98173

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the FAM3 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG410IKQR Eukaryota
ENOG410ZQT7 LUCA

Ensembl GeneTree

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GeneTreei
ENSGT00940000153843

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
HOG000285992

The HOVERGEN Database of Homologous Vertebrate Genes

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HOVERGENi
HBG051544

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
P98173

Database of Orthologous Groups

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OrthoDBi
1295040at2759

Database for complete collections of gene phylogenies

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PhylomeDBi
P98173

TreeFam database of animal gene trees

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TreeFami
TF353414

Family and domain databases

Conserved Domains Database

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CDDi
cd13940 ILEI_FAM3C, 1 hit

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR039220 FAM3
IPR039221 FAM3A
IPR039477 ILEI/PANDER_dom
IPR039475 ILEI_FAM3C

The PANTHER Classification System

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PANTHERi
PTHR14592 PTHR14592, 1 hit
PTHR14592:SF11 PTHR14592:SF11, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF15711 ILEI, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 10 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: P98173-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MRLAGPLRIV VLVVSVGVTW IVVSILLGGP GSGFPRIQQL FTSPESSVTA
60 70 80 90 100
APRARKYKCG LPQPCPEEHL AFRVVSGAAN VIGPKICLED KMLMSSVKDN
110 120 130 140 150
VGRGLNIALV NGVSGELIEA RAFDMWAGDV NDLLKFIRPL HEGTLVFVAS
160 170 180 190 200
YDDPATKMNE ETRKLFSELG SRNAKELAFR DSWVFVGAKG VQNKSPFEQH
210 220 230
VKNSKHSNKY EGWPEALEME GCIPRRSTAS
Length:230
Mass (Da):25,152
Last modified:November 28, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFE23EE191F98CAAD
GO
Isoform 2 (identifier: P98173-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     112-128: Missing.

Note: No experimental confirmation available.
Show »
Length:213
Mass (Da):23,361
Checksum:iF586DA014DEBFF50
GO
Isoform 3 (identifier: P98173-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     6-43: Missing.

Note: Gene prediction based on EST data.
Show »
Length:192
Mass (Da):21,164
Checksum:iB7E349DBE65E0A36
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9BU27Q9BU27_HUMAN
FAM3A protein
FAM3A
70Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5HY75Q5HY75_HUMAN
Protein FAM3A
FAM3A
237Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A6QRH7A6QRH7_HUMAN
Protein FAM3A
FAM3A
163Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WEW8F8WEW8_HUMAN
Protein FAM3A
FAM3A
53Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WEM7F8WEM7_HUMAN
Protein FAM3A
FAM3A
51Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WD39F8WD39_HUMAN
Protein FAM3A
FAM3A
77Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3DWX8D3DWX8_HUMAN
Family with sequence similarity 3, ...
FAM3A hCG_41348
244Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WCK6F8WCK6_HUMAN
Protein FAM3A
FAM3A
70Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A6QRH8A6QRH8_HUMAN
Protein FAM3A
FAM3A
21Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WB47F8WB47_HUMAN
Protein FAM3A
FAM3A
39Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05753121I → M. Corresponds to variant dbSNP:rs35985994Ensembl.1
Natural variantiVAR_011923213W → C3 PublicationsCorresponds to variant dbSNP:rs1050788Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0467336 – 43Missing in isoform 3. CuratedAdd BLAST38
Alternative sequenceiVSP_042778112 – 128Missing in isoform 2. 1 PublicationAdd BLAST17

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X55448 Genomic DNA Translation: CAA39090.1
X87193 mRNA Translation: CAA60645.1
L44140 Genomic DNA Translation: AAA92652.1
AK294116 mRNA Translation: BAG57449.1
AK314682 mRNA Translation: BAG37234.1
BX664739 Genomic DNA No translation available.
CH471172 Genomic DNA Translation: EAW72689.1
CH471172 Genomic DNA Translation: EAW72692.1
CH471172 Genomic DNA Translation: EAW72693.1
CH471172 Genomic DNA Translation: EAW72694.1
CH471172 Genomic DNA Translation: EAW72695.1
BC008912 mRNA Translation: AAH08912.1

The Consensus CDS (CCDS) project

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CCDSi
CCDS35453.1 [P98173-1]
CCDS55542.1 [P98173-3]
CCDS55543.1 [P98173-2]

Protein sequence database of the Protein Information Resource

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PIRi
I37095

NCBI Reference Sequences

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RefSeqi
NP_001164603.1, NM_001171132.2 [P98173-1]
NP_001164604.1, NM_001171133.2 [P98173-3]
NP_001164605.1, NM_001171134.2 [P98173-2]
NP_001269240.1, NM_001282311.1
NP_001269241.1, NM_001282312.1 [P98173-1]
NP_068578.2, NM_021806.3 [P98173-1]
XP_005277936.1, XM_005277879.4 [P98173-2]

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Hs.289108

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000359889; ENSP00000352955; ENSG00000071889 [P98173-1]
ENST00000369643; ENSP00000358657; ENSG00000071889 [P98173-1]
ENST00000393572; ENSP00000377202; ENSG00000071889 [P98173-3]
ENST00000419205; ENSP00000393086; ENSG00000071889 [P98173-2]
ENST00000447601; ENSP00000416146; ENSG00000071889 [P98173-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
60343

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
hsa:60343

UCSC genome browser

More...
UCSCi
uc004fls.4 human [P98173-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X55448 Genomic DNA Translation: CAA39090.1
X87193 mRNA Translation: CAA60645.1
L44140 Genomic DNA Translation: AAA92652.1
AK294116 mRNA Translation: BAG57449.1
AK314682 mRNA Translation: BAG37234.1
BX664739 Genomic DNA No translation available.
CH471172 Genomic DNA Translation: EAW72689.1
CH471172 Genomic DNA Translation: EAW72692.1
CH471172 Genomic DNA Translation: EAW72693.1
CH471172 Genomic DNA Translation: EAW72694.1
CH471172 Genomic DNA Translation: EAW72695.1
BC008912 mRNA Translation: AAH08912.1
CCDSiCCDS35453.1 [P98173-1]
CCDS55542.1 [P98173-3]
CCDS55543.1 [P98173-2]
PIRiI37095
RefSeqiNP_001164603.1, NM_001171132.2 [P98173-1]
NP_001164604.1, NM_001171133.2 [P98173-3]
NP_001164605.1, NM_001171134.2 [P98173-2]
NP_001269240.1, NM_001282311.1
NP_001269241.1, NM_001282312.1 [P98173-1]
NP_068578.2, NM_021806.3 [P98173-1]
XP_005277936.1, XM_005277879.4 [P98173-2]
UniGeneiHs.289108

3D structure databases

ProteinModelPortaliP98173
SMRiP98173
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi121898, 13 interactors
IntActiP98173, 3 interactors
MINTiP98173
STRINGi9606.ENSP00000352955

PTM databases

iPTMnetiP98173

Polymorphism and mutation databases

BioMutaiFAM3A

Proteomic databases

EPDiP98173
jPOSTiP98173
MaxQBiP98173
PaxDbiP98173
PeptideAtlasiP98173
PRIDEiP98173
ProteomicsDBi57807
57808 [P98173-2]

Protocols and materials databases

The DNASU plasmid repository

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DNASUi
60343
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000359889; ENSP00000352955; ENSG00000071889 [P98173-1]
ENST00000369643; ENSP00000358657; ENSG00000071889 [P98173-1]
ENST00000393572; ENSP00000377202; ENSG00000071889 [P98173-3]
ENST00000419205; ENSP00000393086; ENSG00000071889 [P98173-2]
ENST00000447601; ENSP00000416146; ENSG00000071889 [P98173-1]
GeneIDi60343
KEGGihsa:60343
UCSCiuc004fls.4 human [P98173-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
60343
EuPathDBiHostDB:ENSG00000071889.16

GeneCards: human genes, protein and diseases

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GeneCardsi
FAM3A

H-Invitational Database, human transcriptome db

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H-InvDBi
HIX0017160
HGNCiHGNC:13749 FAM3A
HPAiCAB025016
HPA056991
MIMi300492 gene
neXtProtiNX_P98173
OpenTargetsiENSG00000071889
PharmGKBiPA38366

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiENOG410IKQR Eukaryota
ENOG410ZQT7 LUCA
GeneTreeiENSGT00940000153843
HOGENOMiHOG000285992
HOVERGENiHBG051544
InParanoidiP98173
OrthoDBi1295040at2759
PhylomeDBiP98173
TreeFamiTF353414

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
FAM3A human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
60343

Protein Ontology

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PROi
PR:P98173

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000071889 Expressed in 209 organ(s), highest expression level in lower esophagus mucosa
CleanExiHS_FAM3A
ExpressionAtlasiP98173 baseline and differential
GenevisibleiP98173 HS

Family and domain databases

CDDicd13940 ILEI_FAM3C, 1 hit
InterProiView protein in InterPro
IPR039220 FAM3
IPR039221 FAM3A
IPR039477 ILEI/PANDER_dom
IPR039475 ILEI_FAM3C
PANTHERiPTHR14592 PTHR14592, 1 hit
PTHR14592:SF11 PTHR14592:SF11, 1 hit
PfamiView protein in Pfam
PF15711 ILEI, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFAM3A_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P98173
Secondary accession number(s): A6QRH6
, B2RBI7, B4DFI8, D3DWX4, Q5HY76, Q96H51
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: November 28, 2006
Last modified: January 16, 2019
This is version 146 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
UniProt is an ELIXIR core data resource
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