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Entry version 121 (12 Aug 2020)
Sequence version 1 (01 Feb 1996)
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Protein

Hemocytin

Gene
N/A
Organism
Bombyx mori (Silk moth)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Adhesive protein and relates to hemostasis or encapsulation of foreign substances for self-defense.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell adhesion
LigandLectin

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Hemocytin
Alternative name(s):
Humoral lectin
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBombyx mori (Silk moth)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7091 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaLepidopteraGlossataDitrysiaBombycoideaBombycidaeBombycinaeBombyx
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005204 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – ?Sequence analysis
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_0000021445? – 3133Hemocytin

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi? ↔ 3075By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi151N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi237N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi564N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi940 ↔ 1095By similarity
Disulfide bondi1116 ↔ 1254By similarity
Glycosylationi1170N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1387N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1622N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1727N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1847N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1975N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1985N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2093N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2113N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2161N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2276N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2451N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2647N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2654N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2663N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2794N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2810N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2865N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2929N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2964N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi2971 ↔ 3040By similarity
Disulfide bondi2991 ↔ 3054By similarity
Disulfide bondi3004 ↔ 3070By similarity
Disulfide bondi3020 ↔ 3072By similarity
Glycosylationi3028N-linked (GlcNAc...) asparagineSequence analysis1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

May be converted into the 260 kDa mature hemocytin by proteolysis.

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
P98092

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed in hemocytes during larval-pupal metamorphosis.

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Hemagglutination activity is increased by bacterial or viral infection and inhibited by D-mannose, N-acetyl-D-galactosamine and D-maltose.

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7091.BGIBMGA006692-TA

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P98092

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini40 – 96TIL 1Add BLAST57
Domaini153 – 209TIL 2Add BLAST57
Domaini248 – 455VWFD 1PROSITE-ProRule annotationAdd BLAST208
Domaini509 – 576TIL 3Add BLAST68
Domaini770 – 837TIL 4Add BLAST68
Domaini940 – 1095F5/8 type C 1PROSITE-ProRule annotationAdd BLAST156
Domaini1116 – 1254F5/8 type C 2PROSITE-ProRule annotationAdd BLAST139
Domaini1619 – 1824VWFD 2PROSITE-ProRule annotationAdd BLAST206
Domaini1890 – 1948TIL 5Add BLAST59
Domaini1953 – 2179VWFD 3PROSITE-ProRule annotationAdd BLAST227
Domaini2229 – 2285TIL 6Add BLAST57
Domaini2553 – 2622VWFC 1Add BLAST70
Domaini2842 – 2907VWFC 2Add BLAST66
Domaini2971 – 3076CTCKPROSITE-ProRule annotationAdd BLAST106

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi895 – 914Poly-ThrAdd BLAST20
Compositional biasi1267 – 1270Poly-Glu4
Compositional biasi1425 – 1428Poly-Thr4
Compositional biasi1447 – 1450Poly-Thr4
Compositional biasi1474 – 1479Poly-Ser6
Compositional biasi2148 – 2153Poly-Pro6
Compositional biasi2156 – 2159Poly-Pro4
Compositional biasi2341 – 2344Poly-Pro4

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1216, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_361397_0_0_1

Database of Orthologous Groups

More...
OrthoDBi
12226at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00057, FA58C, 2 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.120.260, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006207, Cys_knot_C
IPR000421, FA58C
IPR008979, Galactose-bd-like_sf
IPR012111, Hml
IPR036084, Ser_inhib-like_sf
IPR002919, TIL_dom
IPR014853, Unchr_dom_Cys-rich
IPR001007, VWF_dom
IPR001846, VWF_type-D

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08742, C8, 3 hits
PF00754, F5_F8_type_C, 2 hits
PF01826, TIL, 4 hits
PF00094, VWD, 3 hits

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF036569, Hml, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00832, C8, 3 hits
SM00041, CT, 1 hit
SM00231, FA58C, 2 hits
SM00214, VWC, 5 hits
SM00215, VWC_out, 1 hit
SM00216, VWD, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49785, SSF49785, 2 hits
SSF57567, SSF57567, 4 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01185, CTCK_1, 1 hit
PS01225, CTCK_2, 1 hit
PS01285, FA58C_1, 2 hits
PS01286, FA58C_2, 2 hits
PS50022, FA58C_3, 2 hits
PS51233, VWFD, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P98092-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRGGRDPVPV PVLGDYAMVC AKNGIILQWR YNVKECELSC TGGQQYTVCA
60 70 80 90 100
DSCLRKCSDT ALAASGQCKP VCVEGCACSP SQLLDDNGVC VPVAKCPCIH
110 120 130 140 150
KGLQFNAGYK EIRPGRRERE LCTCVGARWD CKPATPEEIQ NYPPAEDLRS
160 170 180 190 200
NSTAQNMEFT TCETSEPLTC KNMHLPPSTQ TAECRPGCQC KKGQVLDTAS
210 220 230 240 250
KRCVPATQCP CHHAGRSYPD GHLMQEECNK CECKNGNWSC TQRKCAGVCG
260 270 280 290 300
AWGDSHVNTF DGTQYDFEGV CTYLLAKGAM DGTDGFDVEI QNVPCGTTGA
310 320 330 340 350
TCSKSVTLKV GGAGNEEIVS LTKNAPIPDI SKLKRIKMRK AGAYVFLDVP
360 370 380 390 400
SLGMSLQWDR GLRVYVKIDT MWQGRVKGLC GNYNGDMRDD FQTPSGGGMS
410 420 430 440 450
ESSALIFADS WKLKPTCPKP QPVIDHCKQR PERKEWAQSV CGALKRYPFS
460 470 480 490 500
LCAGEVGAGA YVARCERDAC DAGADCECAC AALAAYAHAC AHRGVTFNWR
510 520 530 540 550
TNDLCPMQCD EVCSNYDSCV SACPVETCDN ILYYAETTAR CEQDTCVEGC
560 570 580 590 600
KPKKSCPEGS VYKNDSTTEC VPRAKCKPVC MTLDGGREVL EGEIIEEDAC
610 620 630 640 650
HTCRCSKKHK VCTGQPCSTE APRIQATSSS AEPATERPHE PLKCVTGWTP
660 670 680 690 700
WINRGPAEIG PDGQSVESEP LPKPNELQIG KPMCKPEMMK KIECRTVNDH
710 720 730 740 750
KTPKETGLNV ECSLENGLVC EEPEKTCPDF EIKVYCECEE PQDTSPPVTV
760 770 780 790 800
TSEASSEPVS TTLATTTSRC PPGEVYQACA YKCDRLCDHF KKTLIAKGRC
810 820 830 840 850
ISEMCVDGCV DESVASNGCE GSSRWRDERT CVPVKDCTCY NDGQIVKPGG
860 870 880 890 900
VTESGCIKCQ CLDNSLYCDS KDCVSLNIPH QGSTHLPYIV RPVSTTITST
910 920 930 940 950
TTTTTTSTTT TTTTPEPTET TTETTVPLII KSTVSPPPEC SPDNYIDLVM
960 970 980 990 1000
GDEPLPDTAF SASSEFSEIF APHNARLNRG PTNSGAGSWN PKVNNDKQYI
1010 1020 1030 1040 1050
QVELPRREPI YGVVLQGSPI FDQYVTSYEI MYGDDGNTFS TVDGPDGKPK
1060 1070 1080 1090 1100
IFRGPIDNTH PVKQMISPPI EAKVVRIRPL TWHDEISLRL EIIGCAEPLT
1110 1120 1130 1140 1150
TETSEPSPTS ESPLQCTEPL GLIGELPLEN IQVSSNSEEK DYLSINGNRG
1160 1170 1180 1190 1200
WKPLYNTPGW VMFDFTGPRN ITGILTKGGN DGWVTSYKVL YTSDFETFNP
1210 1220 1230 1240 1250
VIDKDGKEKI FPANFDGIVS VTNEFHPPIR ARYLKVLPQK WNKNIELRIE
1260 1270 1280 1290 1300
PIGCFEPYPE ILRSLPEEEE GREEPQVVRK EYGMSQEREM PNCHICPGVE
1310 1320 1330 1340 1350
AKECTCSYPE YFDGENCVPR AECPCVESFM TYPVGSTFRG ANCDECVCKL
1360 1370 1380 1390 1400
GGTTECKPFK ECQCDDESLV PKLSPTTCDC TCEPCTNGTK ICKTSKLCLA
1410 1420 1430 1440 1450
LESWCDGVQD CPDDERDCTT STARTTTTEP TVVTTVAPTQ AATAPPTTTT
1460 1470 1480 1490 1500
PKPVVECPKV ECPPGYIISY TTGSSSSYSR AFSSDLPPPR PRYSYQRYYR
1510 1520 1530 1540 1550
GRSTGGYSGY AKTGYSKGGF SKGGFSKGGY GYPSIPRSNQ AFTLDKPALT
1560 1570 1580 1590 1600
NKQPTSKEEC AQFKCISKLP AFKPGVVPPP VACSVVTCPA GYTLKLDKVP
1610 1620 1630 1640 1650
TGYNKCPQYE CVPPLERPVF CNMTGRTFNT FDGMEYKYDV CFHMLARDNK
1660 1670 1680 1690 1700
FDAWLIIVRK NCRLDGCTNE LIVMQDDQLI QVKPNMMVTY NNYEYTIEQT
1710 1720 1730 1740 1750
KKICFQKNSF DVDRLGNGIS ITSRKYNFTV LFNKEGDVKI GVLKKHMGGV
1760 1770 1780 1790 1800
DGLCGAYDGS LANERRLPDG RVATSIDEFG RSWAKPGVPA DACAPRVASA
1810 1820 1830 1840 1850
HKQRRAWDLC NVIAEEPFSQ CGKVLNLDKW RHICLEKICE CTDLVVNGTK
1860 1870 1880 1890 1900
RTEEQCRCLV LQQMAAECLA ADAGVDLASW RLMMDCPADC PPPLVHYDCY
1910 1920 1930 1940 1950
RKRCEETCAP YPNAARACPA QEGQCSPGCY CPDGKLRKGD QCVLPADCLD
1960 1970 1980 1990 2000
CTCTGVGTPA KYTTFEGDDL PFLGNCTYLA SRDRNQTGEH KYQVYATNGP
2010 2020 2030 2040 2050
CDDNANIVCT KIVHLIYEKN VIHISKDPTT KKLRTVIGKT AVFKYPVKEN
2060 2070 2080 2090 2100
WGTISLLNGQ DVSVTLPDIH VELTVSQLNL EFAVRVPTFL YGNRTEGLCG
2110 2120 2130 2140 2150
VCAGYQDFLV TSNGTVTDDF DLYGKSWQAS PEKLTELEVP SDEQCDAPPP
2160 2170 2180 2190 2200
PAPCTPPPPD NNTCYHLYNA DRFGACHALV EPQPYVESCE ADECGGHGPC
2210 2220 2230 2240 2250
DALQRYAAAC AELGLCLPDW RRELCPYPCE EPFVYRACVD CERTCDNYEQ
2260 2270 2280 2290 2300
LQTSPEKCTN KPVEGCFCPE GKVRVNNTCI EPGKCFPCGV DGHYAGDEWQ
2310 2320 2330 2340 2350
EDASTLCACA RSPHGTALVG CRATSCAPPV CAHGEDLRTA PPPPGQCCPE
2360 2370 2380 2390 2400
YDCVAKPEAQ CKETKKIVCD YGQVLKQKTN PSGCKEYFCE CKPSSECEVI
2410 2420 2430 2440 2450
PPESEVEIVE AGIHREIDNS GCCPRVSLVC RPETCPKPPH CPQFQTLASV
2460 2470 2480 2490 2500
NITGKCCPEY KCELPKDKCI VTLEWEAAAK GGEKPREKPQ TVLKDLEAVW
2510 2520 2530 2540 2550
LDGPCRSCEC ALSGAGPAAT CAVSACPAVV SSELFVLEPR PVPFACCPEP
2560 2570 2580 2590 2600
VQVACRHQDN VYKVGEKWKS PTDVCETYEC AADGDGKLQR LAAVQRCDRH
2610 2620 2630 2640 2650
CQPGWKYVPA EADSGQCCGK CEPVACVVDG EEKPIGEKWT SSDFCTNFTC
2660 2670 2680 2690 2700
VNLNGTLQVQ SSNETCPEIS DAERKQFVLK EQKVPGKCCP KIEREACTSG
2710 2720 2730 2740 2750
RSDIPGRREL DVDRELVREL PMRAGRGRRP ALRGLRAALR DRLPTRLEVL
2760 2770 2780 2790 2800
PAPAECCGRC KPSPASWKGG RGPSGRARER PVGESWTSAD FCTNYTCADL
2810 2820 2830 2840 2850
HGTLQVQSSN ETCPEVSEAV KKQFVLKEEK IPGKCCPKVE PVACRDGDKI
2860 2870 2880 2890 2900
YQEVQVWTTP DPCTNRTCRR EDGQLSVGRT VEHCERQCRR GWTYSPPAAD
2910 2920 2930 2940 2950
HCCGRCVQSA CLVDDQLKEP GSTWSSADNC TTFSCDRSGE EVFVTSATEH
2960 2970 2980 2990 3000
CPDVSACDPA DIVNTTCCQI CNEKPQALSK CVLRASELRH CRSDPHPMGA
3010 3020 3030 3040 3050
HGLCVNKFPI TGFTEVHGSC DSGTIYNNQT GTHESACECC QAAKYSGVSV
3060 3070 3080 3090 3100
RLTCEDGTVR PHRVATPARC HCAACGPGLT KHPKPGHASY TGTKNPVQPE
3110 3120 3130
RDREYVIPDI SSASGEARRN HDSNYITTLI ISF
Length:3,133
Mass (Da):343,355
Last modified:February 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE5210D5D14A7B2B2
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural varianti1288R → G. 1
Natural varianti1305T → S. 1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
D29738 mRNA Translation: BAA06160.1
D14035 mRNA Translation: BAA03124.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S52093

NCBI Reference Sequences

More...
RefSeqi
NP_001104817.1, NM_001111347.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
692743

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
bmor:692743

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D29738 mRNA Translation: BAA06160.1
D14035 mRNA Translation: BAA03124.1
PIRiS52093
RefSeqiNP_001104817.1, NM_001111347.1

3D structure databases

SMRiP98092
ModBaseiSearch...

Protein-protein interaction databases

STRINGi7091.BGIBMGA006692-TA

Proteomic databases

PRIDEiP98092

Genome annotation databases

GeneIDi692743
KEGGibmor:692743

Phylogenomic databases

eggNOGiKOG1216, Eukaryota
HOGENOMiCLU_361397_0_0_1
OrthoDBi12226at2759

Family and domain databases

CDDicd00057, FA58C, 2 hits
Gene3Di2.60.120.260, 2 hits
InterProiView protein in InterPro
IPR006207, Cys_knot_C
IPR000421, FA58C
IPR008979, Galactose-bd-like_sf
IPR012111, Hml
IPR036084, Ser_inhib-like_sf
IPR002919, TIL_dom
IPR014853, Unchr_dom_Cys-rich
IPR001007, VWF_dom
IPR001846, VWF_type-D
PfamiView protein in Pfam
PF08742, C8, 3 hits
PF00754, F5_F8_type_C, 2 hits
PF01826, TIL, 4 hits
PF00094, VWD, 3 hits
PIRSFiPIRSF036569, Hml, 1 hit
SMARTiView protein in SMART
SM00832, C8, 3 hits
SM00041, CT, 1 hit
SM00231, FA58C, 2 hits
SM00214, VWC, 5 hits
SM00215, VWC_out, 1 hit
SM00216, VWD, 3 hits
SUPFAMiSSF49785, SSF49785, 2 hits
SSF57567, SSF57567, 4 hits
PROSITEiView protein in PROSITE
PS01185, CTCK_1, 1 hit
PS01225, CTCK_2, 1 hit
PS01285, FA58C_1, 2 hits
PS01286, FA58C_2, 2 hits
PS50022, FA58C_3, 2 hits
PS51233, VWFD, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiHMCT_BOMMO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P98092
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: August 12, 2020
This is version 121 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome
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