UniProtKB - P97817 (CDR2_MOUSE)
Protein
Cerebellar degeneration-related protein 2
Gene
Cdr2
Organism
Mus musculus (Mouse)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Cerebellar degeneration-related protein 2 |
Gene namesi | Name:Cdr2 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1100885 Cdr2 |
Subcellular locationi
Other locations
- cytoplasm Source: MGI
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000089457 | 1 – 455 | Cerebellar degeneration-related protein 2Add BLAST | 455 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 310 | PhosphoserineBy similarity | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
jPOSTi | P97817 |
MaxQBi | P97817 |
PaxDbi | P97817 |
PeptideAtlasi | P97817 |
PRIDEi | P97817 |
PTM databases
iPTMneti | P97817 |
PhosphoSitePlusi | P97817 |
Expressioni
Tissue specificityi
Expressed in brain and testis (at protein level). Expressed in the cerebellum, cerebral cortex, heart, lung, spleen, ovary, kidney and testis.1 Publication
Gene expression databases
Bgeei | ENSMUSG00000030878 Expressed in 281 organ(s), highest expression level in blood |
ExpressionAtlasi | P97817 baseline and differential |
Genevisiblei | P97817 MM |
Interactioni
Protein-protein interaction databases
BioGridi | 198660, 1 interactor |
STRINGi | 10090.ENSMUSP00000033169 |
Structurei
3D structure databases
ProteinModelPortali | P97817 |
SMRi | P97817 |
ModBasei | Search... |
MobiDBi | Search... |
Family & Domainsi
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 37 – 141 | Sequence analysisAdd BLAST | 105 | |
Coiled coili | 191 – 264 | Sequence analysisAdd BLAST | 74 |
Sequence similaritiesi
Belongs to the CDR2 family.Curated
Keywords - Domaini
Coiled coilPhylogenomic databases
eggNOGi | ENOG410IDY5 Eukaryota ENOG410XNUZ LUCA |
GeneTreei | ENSGT00390000018570 |
HOGENOMi | HOG000013160 |
HOVERGENi | HBG006695 |
InParanoidi | P97817 |
OMAi | RQMNDQH |
OrthoDBi | 1101523at2759 |
TreeFami | TF326183 |
Family and domain databases
InterProi | View protein in InterPro IPR026079 CDR2 |
PANTHERi | PTHR19232 PTHR19232, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
P97817-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLADNLVEEF EMEDEPWYDH RDLQQDLQLA AELGKTLLDR NTELEDSLQQ
60 70 80 90 100
MYTTNQEQLQ EIEYLTKQVE LLRQMNEQHA KVYEQLDVTA RELEETNQKL
110 120 130 140 150
VAESKASQQK ILSLTETIEC LQTNIDHLQS QVEELKSSSQ GRGRQKACDQ
160 170 180 190 200
EKPAPSFSCL KELYDLRQHF VYDHVFAEKI TSLQSQQSPD EEENEHLKKA
210 220 230 240 250
VTMLQAQLSL ERKKRVSVEA EYKVVLKENS ELEQQLGATD AYRARALELE
260 270 280 290 300
AEVAEMRQML QAEHPFVNGV EKLVPDSLFV PFKEPSQSLL EEMFLAAPEA
310 320 330 340 350
PRKPLKRSSS ETALSSLAGD DIVKDHEDTC IRRAKAVKQR GISLLHEVDT
360 370 380 390 400
QYSALKVKYE ELLKKCQQEQ DSLSHKAVQT SRLLTRDLTG LVTQSEAGAS
410 420 430 440 450
GWEPTPVSPE SISSPTTTPP EYKALFKEIF SCIKKTKQEI DEQRTKYPSL
SSYSY
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A140LHD9 | A0A140LHD9_MOUSE | Cerebellar degeneration-related pro... | Cdr2 | 91 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 367 – 368 | QQ → HE in AAC53052 (PubMed:9006982).Curated | 2 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U88588 mRNA Translation: AAC53052.1 AK148057 mRNA Translation: BAE28317.1 BC117530 mRNA Translation: AAI17531.1 BC118511 mRNA Translation: AAI18512.1 |
CCDSi | CCDS21798.1 |
RefSeqi | NP_031698.2, NM_007672.2 |
UniGenei | Mm.1640 |
Genome annotation databases
Ensembli | ENSMUST00000033169; ENSMUSP00000033169; ENSMUSG00000030878 |
GeneIDi | 12585 |
KEGGi | mmu:12585 |
UCSCi | uc012ftc.2 mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U88588 mRNA Translation: AAC53052.1 AK148057 mRNA Translation: BAE28317.1 BC117530 mRNA Translation: AAI17531.1 BC118511 mRNA Translation: AAI18512.1 |
CCDSi | CCDS21798.1 |
RefSeqi | NP_031698.2, NM_007672.2 |
UniGenei | Mm.1640 |
3D structure databases
ProteinModelPortali | P97817 |
SMRi | P97817 |
ModBasei | Search... |
MobiDBi | Search... |
Protein-protein interaction databases
BioGridi | 198660, 1 interactor |
STRINGi | 10090.ENSMUSP00000033169 |
PTM databases
iPTMneti | P97817 |
PhosphoSitePlusi | P97817 |
Proteomic databases
jPOSTi | P97817 |
MaxQBi | P97817 |
PaxDbi | P97817 |
PeptideAtlasi | P97817 |
PRIDEi | P97817 |
Protocols and materials databases
Structural Biology Knowledgebase | Search... |
Genome annotation databases
Ensembli | ENSMUST00000033169; ENSMUSP00000033169; ENSMUSG00000030878 |
GeneIDi | 12585 |
KEGGi | mmu:12585 |
UCSCi | uc012ftc.2 mouse |
Organism-specific databases
CTDi | 1039 |
MGIi | MGI:1100885 Cdr2 |
Phylogenomic databases
eggNOGi | ENOG410IDY5 Eukaryota ENOG410XNUZ LUCA |
GeneTreei | ENSGT00390000018570 |
HOGENOMi | HOG000013160 |
HOVERGENi | HBG006695 |
InParanoidi | P97817 |
OMAi | RQMNDQH |
OrthoDBi | 1101523at2759 |
TreeFami | TF326183 |
Miscellaneous databases
PROi | PR:P97817 |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000030878 Expressed in 281 organ(s), highest expression level in blood |
ExpressionAtlasi | P97817 baseline and differential |
Genevisiblei | P97817 MM |
Family and domain databases
InterProi | View protein in InterPro IPR026079 CDR2 |
PANTHERi | PTHR19232 PTHR19232, 1 hit |
ProtoNeti | Search... |
Entry informationi
Entry namei | CDR2_MOUSE | |
Accessioni | P97817Primary (citable) accession number: P97817 Secondary accession number(s): Q3UG92 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 7, 2005 |
Last sequence update: | July 27, 2011 | |
Last modified: | February 13, 2019 | |
This is version 93 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Complete proteome, Direct protein sequencing, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot