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Entry version 149 (02 Jun 2021)
Sequence version 1 (01 May 1997)
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Protein

Protein jagged-2

Gene

Jag2

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Putative Notch ligand involved in the mediation of Notch signaling. May have a role in neurogenesis in the peripheral nervous system, limb development and in the adult brain.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein
Biological processNotch signaling pathway
LigandCalcium

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein jagged-2
Short name:
Jagged2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Jag2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

Rat genome database

More...
RGDi
2938, Jag2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini‹1 – 1037ExtracellularSequence analysisAdd BLAST›1037
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1038 – 1058HelicalSequence analysisAdd BLAST21
Topological domaini1059 – 1202CytoplasmicSequence analysisAdd BLAST144

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_0000055632‹1 – 1202Protein jagged-2Add BLAST›1202

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi107N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi152 ↔ 161By similarity
Disulfide bondi165 ↔ 177By similarity
Disulfide bondi185 ↔ 194By similarity
Disulfide bondi199 ↔ 210By similarity
Disulfide bondi203 ↔ 216By similarity
Disulfide bondi218 ↔ 227By similarity
Disulfide bondi230 ↔ 241By similarity
Disulfide bondi236 ↔ 247By similarity
Disulfide bondi249 ↔ 258By similarity
Disulfide bondi265 ↔ 277By similarity
Disulfide bondi271 ↔ 287By similarity
Disulfide bondi289 ↔ 298By similarity
Disulfide bondi305 ↔ 316By similarity
Disulfide bondi310 ↔ 325By similarity
Disulfide bondi327 ↔ 336By similarity
Disulfide bondi343 ↔ 354By similarity
Disulfide bondi348 ↔ 363By similarity
Disulfide bondi365 ↔ 374By similarity
Disulfide bondi381 ↔ 392By similarity
Disulfide bondi386 ↔ 401By similarity
Disulfide bondi403 ↔ 412By similarity
Disulfide bondi419 ↔ 429By similarity
Disulfide bondi423 ↔ 438By similarity
Disulfide bondi440 ↔ 449By similarity
Disulfide bondi456 ↔ 467By similarity
Disulfide bondi461 ↔ 476By similarity
Disulfide bondi478 ↔ 487By similarity
Disulfide bondi495 ↔ 506By similarity
Disulfide bondi500 ↔ 515By similarity
Disulfide bondi517 ↔ 526By similarity
Glycosylationi525N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi544 ↔ 567Sequence analysis
Disulfide bondi561 ↔ 577Sequence analysis
Glycosylationi574N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi579 ↔ 588By similarity
Disulfide bondi595 ↔ 606By similarity
Disulfide bondi600 ↔ 615By similarity
Disulfide bondi617 ↔ 626By similarity
Disulfide bondi633 ↔ 644By similarity
Disulfide bondi638 ↔ 653By similarity
Disulfide bondi655 ↔ 664By similarity
Disulfide bondi671 ↔ 682By similarity
Disulfide bondi676 ↔ 691By similarity
Disulfide bondi693 ↔ 702By similarity
Glycosylationi707N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi710 ↔ 721By similarity
Disulfide bondi715 ↔ 730By similarity
Disulfide bondi732 ↔ 741By similarity
Disulfide bondi748 ↔ 759By similarity
Disulfide bondi753 ↔ 768By similarity
Disulfide bondi770 ↔ 779By similarity
Disulfide bondi786 ↔ 797By similarity
Disulfide bondi791 ↔ 806By similarity
Disulfide bondi808 ↔ 817By similarity
Glycosylationi1015N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1080PhosphoserineBy similarity1

Keywords - PTMi

Disulfide bond, Glycoprotein, Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P97607

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P97607

PRoteomics IDEntifications database

More...
PRIDEi
P97607

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
P97607, 5 sites

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

At stage E12.5 it is detected in dorsal root ganglia, AER, and surface ectoderm. At E14.5, found as well in cranial ganglia, thymus and olfactory epithelia. At E16.5, found as well in salivary gland, tooth buds and hair follicles.

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000019213

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P97607

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini150 – 194DSLPROSITE-ProRule annotationAdd BLAST45
Domaini195 – 228EGF-like 1PROSITE-ProRule annotationAdd BLAST34
Domaini229 – 259EGF-like 2; atypicalPROSITE-ProRule annotationAdd BLAST31
Domaini261 – 299EGF-like 3PROSITE-ProRule annotationAdd BLAST39
Domaini301 – 337EGF-like 4PROSITE-ProRule annotationAdd BLAST37
Domaini339 – 375EGF-like 5; calcium-bindingPROSITE-ProRule annotationAdd BLAST37
Domaini377 – 413EGF-like 6; calcium-bindingPROSITE-ProRule annotationAdd BLAST37
Domaini415 – 450EGF-like 7; calcium-bindingPROSITE-ProRule annotationAdd BLAST36
Domaini452 – 488EGF-like 8PROSITE-ProRule annotationAdd BLAST37
Domaini490 – 527EGF-like 9PROSITE-ProRule annotationAdd BLAST38
Domaini529 – 589EGF-like 10; atypicalPROSITE-ProRule annotationAdd BLAST61
Domaini591 – 627EGF-like 11; calcium-bindingPROSITE-ProRule annotationAdd BLAST37
Domaini629 – 665EGF-like 12; calcium-bindingPROSITE-ProRule annotationAdd BLAST37
Domaini667 – 703EGF-like 13PROSITE-ProRule annotationAdd BLAST37
Domaini706 – 742EGF-like 14PROSITE-ProRule annotationAdd BLAST37
Domaini744 – 780EGF-like 15; calcium-bindingPROSITE-ProRule annotationAdd BLAST37
Domaini782 – 818EGF-like 16; calcium-bindingPROSITE-ProRule annotationAdd BLAST37

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1070 – 1202DisorderedSequence analysisAdd BLAST133

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1188 – 1202Basic and acidic residuesSequence analysisAdd BLAST15

Keywords - Domaini

EGF-like domain, Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1217, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P97607

Identification of Orthologs from Complete Genome Data

More...
OMAi
GAFRCFC

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P97607

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001774, DSL
IPR001881, EGF-like_Ca-bd_dom
IPR013032, EGF-like_CS
IPR000742, EGF-like_dom
IPR000152, EGF-type_Asp/Asn_hydroxyl_site
IPR018097, EGF_Ca-bd_CS
IPR009030, Growth_fac_rcpt_cys_sf
IPR026219, Jagged/Serrate
IPR011651, Notch_ligand_N
IPR001007, VWF_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01414, DSL, 1 hit
PF00008, EGF, 9 hits
PF07645, EGF_CA, 1 hit
PF12661, hEGF, 3 hits
PF07657, MNNL, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR02059, JAGGEDFAMILY

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00051, DSL, 1 hit
SM00181, EGF, 16 hits
SM00179, EGF_CA, 14 hits
SM00215, VWC_out, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57184, SSF57184, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00010, ASX_HYDROXYL, 10 hits
PS51051, DSL, 1 hit
PS00022, EGF_1, 15 hits
PS01186, EGF_2, 11 hits
PS50026, EGF_3, 15 hits
PS01187, EGF_CA, 7 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

P97607-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
GACCDGDGRT TRAGGCGRDE CDTYVRVCLK EYQAKVTPTG PCSYGYGATP
60 70 80 90 100
VLGSNSFYLP PAGAAGDRAR ARSRTGGHQD PGLVVIPFQF AWPRSFTLIV
110 120 130 140 150
EAWDWDNDTT PDEELLIERV SHAGMINPED RWKSLHFSGH VAHLELQIRV
160 170 180 190 200
RCDENYYSAT CNKFCRPRND FFGHYTCDQY GNKACMDGWM GKECKEAVCK
210 220 230 240 250
QGCNLLHGGC TVPGECRCSY GWQGKFCDEC VPYPGCVHGS CVEPWHCDCE
260 270 280 290 300
TNWGGLLCDK DLNYCGSHHP CVNGGTCINA EPDQYLCACP DGYLGKNCER
310 320 330 340 350
AEHACASNPC ANGGSCHEVL SGFECHCPSG WSGPTCALDI DECASNPCAA
360 370 380 390 400
GGTCVDQVDG FECICPEQWV GATCQLDANE CEGKPCLNAF SCKNLIGGYY
410 420 430 440 450
CDCLPGWKGA NCHININDCH GQCQHGGTCK DLVNGYQCVC PRGFGGRHCE
460 470 480 490 500
LEYYKCASSP CRRGGICEDL VDGFRCHCPR GLSGPLCEVD VDLWCEPNPC
510 520 530 540 550
LNGARCYNLE DDYYCACPED FGGKNCSVPR ETCPGGACRV IDGCGFEAGS
560 570 580 590 600
RAHGAAPSGV CGPHGHCVSL PGGNFSCICD SGFTGTYCHE NIDDCMGQPC
610 620 630 640 650
RNGGTCIDEV DSFACFCPSG WEGELCDINP NDCLPDPCHS RGRCYDLVND
660 670 680 690 700
FYCVCDDGWK DKTCHSREFQ CDAYTCSNGG TCYDSGDTFR CACPPGWKGS
710 720 730 740 750
TCTIAKNSSC VPNPCVNGGT CVGSGDSFSC ICRDGWEGRT CTHNTNDCNP
760 770 780 790 800
LPCYNGGICV DGVNWFRCEC APGFAGPDCR INIDECQSSP CAYGATCVDE
810 820 830 840 850
INGYRCSCPP GRSGPRCQEV VIFTRPCWSR GVSFPHGSSW VEDCNSCRCL
860 870 880 890 900
DGHRDCSKVW CGWKPCLLSP QPSALSAQCP PGQQCREKAM GQCLQPPCEN
910 920 930 940 950
WGECTAEDPL PPSTPCLPRT THLDNNCARL TLHFNRDQVP QGTTVGAICS
960 970 980 990 1000
GIRALPATRA AARDRLLLLL CDRASSGASA VEVAVSFSPA RDLPDSSLIQ
1010 1020 1030 1040 1050
STAHAIVAAI TQRGNSSLLL AVTEVKVETV VMGGSSTGLL VPVLCSVFSV
1060 1070 1080 1090 1100
LWLACMVICV WWTRKRRKER ERSRLPRDES ANNQWAPLNP IRNPIERPGS
1110 1120 1130 1140 1150
SGLGTGGHKD VLYQCKNFTP PPRRAGEALP GPASHGAGGE DEEDEELSRG
1160 1170 1180 1190 1200
DGRLSRSREV PLTQIHQRPQ LLPGKASLLA PGPKVDNRAV RSTKDVRCAG

RE
Length:1,202
Mass (Da):129,705
Last modified:May 1, 1997 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i08CB44E5271FF8BE
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PU23E9PU23_RAT
Delta-like protein
Jag2
1,077Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei11

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U70050 mRNA Translation: AAC52946.1

Genome annotation databases

UCSC genome browser

More...
UCSCi
RGD:2938, rat

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U70050 mRNA Translation: AAC52946.1

3D structure databases

SMRiP97607
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000019213

PTM databases

GlyGeniP97607, 5 sites

Proteomic databases

jPOSTiP97607
PaxDbiP97607
PRIDEiP97607

Genome annotation databases

UCSCiRGD:2938, rat

Organism-specific databases

RGDi2938, Jag2

Phylogenomic databases

eggNOGiKOG1217, Eukaryota
InParanoidiP97607
OMAiGAFRCFC
PhylomeDBiP97607

Family and domain databases

InterProiView protein in InterPro
IPR001774, DSL
IPR001881, EGF-like_Ca-bd_dom
IPR013032, EGF-like_CS
IPR000742, EGF-like_dom
IPR000152, EGF-type_Asp/Asn_hydroxyl_site
IPR018097, EGF_Ca-bd_CS
IPR009030, Growth_fac_rcpt_cys_sf
IPR026219, Jagged/Serrate
IPR011651, Notch_ligand_N
IPR001007, VWF_dom
PfamiView protein in Pfam
PF01414, DSL, 1 hit
PF00008, EGF, 9 hits
PF07645, EGF_CA, 1 hit
PF12661, hEGF, 3 hits
PF07657, MNNL, 1 hit
PRINTSiPR02059, JAGGEDFAMILY
SMARTiView protein in SMART
SM00051, DSL, 1 hit
SM00181, EGF, 16 hits
SM00179, EGF_CA, 14 hits
SM00215, VWC_out, 1 hit
SUPFAMiSSF57184, SSF57184, 2 hits
PROSITEiView protein in PROSITE
PS00010, ASX_HYDROXYL, 10 hits
PS51051, DSL, 1 hit
PS00022, EGF_1, 15 hits
PS01186, EGF_2, 11 hits
PS50026, EGF_3, 15 hits
PS01187, EGF_CA, 7 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiJAG2_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P97607
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 27, 2002
Last sequence update: May 1, 1997
Last modified: June 2, 2021
This is version 149 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome
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