We will be switching to the new UniProt website soon. Please explore and share your feedback.
Take me to the new website.
UniProtKB - P96629 (INT_BACSU)
Protein
ICEBs1 integrase
Gene
int
Organism
Bacillus subtilis (strain 168)
Status
Functioni
Putative integrase that is involved in the insertion of the integrative and conjugative element ICEBs1. Required for the excision of ICEBs1 from the donor cell genome and subsequent integration in the recipient cell genome. Appears not to be transferred through the mating pore. Integration of ICEBs1 involves an attachment site in the chromosome, attB, and a site in the circular form of ICEBs1, attICEBs1.
1 PublicationSites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 201 | PROSITE-ProRule annotation | 1 | |
Active sitei | 239 | PROSITE-ProRule annotation | 1 | |
Active sitei | 313 | PROSITE-ProRule annotation | 1 | |
Active sitei | 316 | PROSITE-ProRule annotation | 1 | |
Active sitei | 339 | PROSITE-ProRule annotation | 1 | |
Active sitei | 349 | O-(3'-phospho-DNA)-tyrosine intermediatePROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- DNA binding Source: UniProtKB-KW
GO - Biological processi
- DNA integration Source: UniProtKB-KW
- DNA recombination Source: UniProtKB-KW
- establishment of integrated proviral latency Source: UniProtKB-KW
- viral entry into host cell Source: UniProtKB-KW
- viral genome integration into host DNA Source: UniProtKB-KW
Keywordsi
Molecular function | DNA-binding |
Biological process | DNA integration, DNA recombination, Viral genome integration, Virus entry into host cell |
Enzyme and pathway databases
BioCyci | BSUB:BSU04800-MONOMER |
Protein family/group databases
TCDBi | 3.A.7.14.3, the type iv (conjugal dna-protein transfer or virb) secretory pathway (ivsp) family |
Names & Taxonomyi
Protein namesi | Recommended name: ICEBs1 integrase |
Gene namesi | Name:int Synonyms:ydcL Ordered Locus Names:BSU04800 |
Organismi | Bacillus subtilis (strain 168) |
Taxonomic identifieri | 224308 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000360640 | 1 – 368 | ICEBs1 integraseAdd BLAST | 368 |
Proteomic databases
PaxDbi | P96629 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 61 – 143 | Core-binding (CB)PROSITE-ProRule annotationAdd BLAST | 83 | |
Domaini | 164 – 362 | Tyr recombinasePROSITE-ProRule annotationAdd BLAST | 199 |
Sequence similaritiesi
Belongs to the 'phage' integrase family.Curated
Phylogenomic databases
eggNOGi | COG0582, Bacteria |
InParanoidi | P96629 |
OMAi | TINKIMI |
PhylomeDBi | P96629 |
Family and domain databases
Gene3Di | 1.10.150.130, 1 hit 1.10.443.10, 1 hit |
InterProi | View protein in InterPro IPR044068, CB IPR011010, DNA_brk_join_enz IPR013762, Integrase-like_cat_sf IPR002104, Integrase_catalytic IPR010998, Integrase_recombinase_N IPR004107, Integrase_SAM-like_N |
Pfami | View protein in Pfam PF14659, Phage_int_SAM_3, 1 hit PF00589, Phage_integrase, 1 hit |
SUPFAMi | SSF56349, SSF56349, 1 hit |
PROSITEi | View protein in PROSITE PS51900, CB, 1 hit PS51898, TYR_RECOMBINASE, 1 hit |
i Sequence
Sequence statusi: Complete.
P96629-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSVKKLENGQ YQVDVSFGFD PITGERIRTR PVASTRKEAL ELEAKLRREF
60 70 80 90 100
QEERARKSRS VSFPTLISIY LASCEIDSKP NYYQNQKYII NKHISDYFLK
110 120 130 140 150
SDIQKITHRE ITDFRKHLME TGLSNKSVNN IMTSLSKIFD TAVHEEILKR
160 170 180 190 200
NPCDNVKRLP LTRKKMKFWR PEEFKKFISL IPQDQLLFKT FYTVAFLTGL
210 220 230 240 250
RCGEMLALQW KDIDKILLEI DVHKSCTWLD GQFVVTTPKT KNSIRRVSIN
260 270 280 290 300
KKLLKLLERW KEAQEELFNE LGIRHSHDTY IFQYKDTPSR KDIFSRKIKY
310 320 330 340 350
FCKDSDLTPI RLHDFRHSHV ALLIHQGEDY ITIKERLGHG SVKTTIDVYG
360
HLYPNKQKEM ADKLDDLL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB001488 Genomic DNA Translation: BAA19318.1 AL009126 Genomic DNA Translation: CAB12287.1 |
PIRi | A69774 |
RefSeqi | NP_388361.1, NC_000964.3 WP_009966615.1, NZ_JNCM01000031.1 |
Genome annotation databases
EnsemblBacteriai | CAB12287; CAB12287; BSU_04800 |
GeneIDi | 938151 |
KEGGi | bsu:BSU04800 |
PATRICi | fig|224308.179.peg.510 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB001488 Genomic DNA Translation: BAA19318.1 AL009126 Genomic DNA Translation: CAB12287.1 |
PIRi | A69774 |
RefSeqi | NP_388361.1, NC_000964.3 WP_009966615.1, NZ_JNCM01000031.1 |
3D structure databases
SMRi | P96629 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 224308.BSU04800 |
Protein family/group databases
TCDBi | 3.A.7.14.3, the type iv (conjugal dna-protein transfer or virb) secretory pathway (ivsp) family |
Proteomic databases
PaxDbi | P96629 |
Genome annotation databases
EnsemblBacteriai | CAB12287; CAB12287; BSU_04800 |
GeneIDi | 938151 |
KEGGi | bsu:BSU04800 |
PATRICi | fig|224308.179.peg.510 |
Phylogenomic databases
eggNOGi | COG0582, Bacteria |
InParanoidi | P96629 |
OMAi | TINKIMI |
PhylomeDBi | P96629 |
Enzyme and pathway databases
BioCyci | BSUB:BSU04800-MONOMER |
Family and domain databases
Gene3Di | 1.10.150.130, 1 hit 1.10.443.10, 1 hit |
InterProi | View protein in InterPro IPR044068, CB IPR011010, DNA_brk_join_enz IPR013762, Integrase-like_cat_sf IPR002104, Integrase_catalytic IPR010998, Integrase_recombinase_N IPR004107, Integrase_SAM-like_N |
Pfami | View protein in Pfam PF14659, Phage_int_SAM_3, 1 hit PF00589, Phage_integrase, 1 hit |
SUPFAMi | SSF56349, SSF56349, 1 hit |
PROSITEi | View protein in PROSITE PS51900, CB, 1 hit PS51898, TYR_RECOMBINASE, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | INT_BACSU | |
Accessioni | P96629Primary (citable) accession number: P96629 Secondary accession number(s): Q797K1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 20, 2009 |
Last sequence update: | May 1, 1997 | |
Last modified: | February 23, 2022 | |
This is version 114 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families