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Protein
Submitted name:

Two component sensor histidine kinase TrcS

Gene

trcS

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalytic activityi

ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.SAAS annotation

GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • calcium ion binding Source: MTBBASE
  • manganese ion binding Source: MTBBASE
  • phosphorelay sensor kinase activity Source: InterPro
  • protein kinase activity Source: MTBBASE

GO - Biological processi

  • protein autophosphorylation Source: MTBBASE

Keywordsi

Molecular functionKinaseSAAS annotationImported, Transferase
Biological processTwo-component regulatory systemSAAS annotation
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Two component sensor histidine kinase TrcSImported
Gene namesi
Name:trcSImported
Ordered Locus Names:Rv1032cImported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001584 Componenti: Chromosome

Organism-specific databases

TubercuListiRv1032c

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiP96368

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv1032c

Structurei

3D structure databases

SMRiP96368
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiENOG4105US7 Bacteria
COG0642 LUCA
HOGENOMiHOG000223177
KOiK07656
OMAiHLFERFV

Family and domain databases

CDDicd00075 HATPase_c, 1 hit
cd00082 HisKA, 1 hit
Gene3Di3.30.565.10, 1 hit
InterProiView protein in InterPro
IPR003660 HAMP_dom
IPR003594 HATPase_C
IPR036890 HATPase_C_sf
IPR005467 His_kinase_dom
IPR003661 HisK_dim/P
IPR036097 HisK_dim/P_sf
IPR004358 Sig_transdc_His_kin-like_C
PfamiView protein in Pfam
PF00672 HAMP, 1 hit
PF02518 HATPase_c, 1 hit
PF00512 HisKA, 1 hit
PRINTSiPR00344 BCTRLSENSOR
SMARTiView protein in SMART
SM00304 HAMP, 1 hit
SM00387 HATPase_c, 1 hit
SM00388 HisKA, 1 hit
SUPFAMiSSF47384 SSF47384, 1 hit
SSF55874 SSF55874, 1 hit
PROSITEiView protein in PROSITE
PS50885 HAMP, 1 hit
PS50109 HIS_KIN, 1 hit

Sequencei

Sequence statusi: Complete.

P96368-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIPDRNTRSR KAPCWRPRSL RQQLLLGVLA VVTVVLVAVG VVSVLSLSGY
60 70 80 90 100
VTAMNDAELV ESLHALNHSY TRYRDSAQTS TPTGNLPMSQ AVLEFTGQTP
110 120 130 140 150
GNLIAVLHDG VVIGSAVFSE DGARPAPPDV IRAIEAQVWD GGPPRVESLG
160 170 180 190 200
SLGAYQVDSS AAGADRLFVG VSLSLANQII ARKKVTTVAL VGAALVVTAA
210 220 230 240 250
LTVWVVGYAL RPLRRVAATA AEVATMPLTD DDHQISVRVR PGDTDPDNEV
260 270 280 290 300
GIVGHTLNRL LDNVDGALAH RVDSDLRMRQ FITDASHELR TPLAAIQGYA
310 320 330 340 350
ELTRQDSSDL PPTTEYALAR IESEARRMTL LVDELLLLSR LSEGEDLETE
360 370 380 390 400
DLDLTDLVIN AVNDAAVAAP THRWVKNLPD EPVWVNGDHA RLHQLVSNLL
410 420 430 440 450
TNAWVHTQPG VTVTIGITCH RTGPNAPCVE LSVTDDGPDI DPEILPHLFD
460 470 480 490 500
RFVRASKSRS NGSGHGLGLA IVSSIVKAHR GSVTAESGNG QTVFRVRLPM

IEQQIATTA
Length:509
Mass (Da):54,591
Last modified:May 1, 1997 - v1
Checksum:i8EA2F0B3DB565922
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL123456 Genomic DNA Translation: CCP43783.1
RefSeqiNP_215548.1, NC_000962.3
WP_003405324.1, NZ_KK339370.1

Genome annotation databases

EnsemblBacteriaiAIR13771; AIR13771; LH57_05645
CCP43783; CCP43783; Rv1032c
GeneIDi887790
KEGGimtu:Rv1032c
mtv:RVBD_1032c
PATRICifig|83332.111.peg.1146

Similar proteinsi

Entry informationi

Entry nameiP96368_MYCTU
AccessioniPrimary (citable) accession number: P96368
Secondary accession number(s): F2GHA7
, I6XAE7, P96908, Q79B74, Q7D8Z0
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: February 28, 2018
This is version 145 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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