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Entry version 119 (11 Dec 2019)
Sequence version 2 (01 Jul 1997)
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Protein
Submitted name:

FK506 polyketide synthase

Gene

fkbA

Organism
Streptomyces sp.
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
FK506 polyketide synthaseImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:fkbAImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiStreptomyces sp.Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1931 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1849O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei3426O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei5342O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei6328O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

PhosphopantetheinePROSITE-ProRule annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1814 – 1889CarrierInterPro annotationAdd BLAST76
Domaini3391 – 3466CarrierInterPro annotationAdd BLAST76
Domaini5307 – 5382CarrierInterPro annotationAdd BLAST76
Domaini6293 – 6368CarrierInterPro annotationAdd BLAST76

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1801 – 1822DisorderedSequence analysisAdd BLAST22
Regioni3009 – 3030DisorderedSequence analysisAdd BLAST22
Regioni4434 – 4458DisorderedSequence analysisAdd BLAST25
Regioni5797 – 5836DisorderedSequence analysisAdd BLAST40
Regioni5896 – 5929DisorderedSequence analysisAdd BLAST34

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1804 – 1822PolarSequence analysisAdd BLAST19
Compositional biasi4436 – 4458PolarSequence analysisAdd BLAST23
Compositional biasi5817 – 5833PolarSequence analysisAdd BLAST17

Phylogenomic databases

KEGG Orthology (KO)

More...
KOi
K16377

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1200.10, 4 hits
3.10.129.110, 3 hits
3.40.366.10, 4 hits
3.40.47.10, 4 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001227 Ac_transferase_dom_sf
IPR036736 ACP-like_sf
IPR014043 Acyl_transferase
IPR016035 Acyl_Trfase/lysoPLipase
IPR013154 ADH_N
IPR011032 GroES-like_sf
IPR032821 KAsynt_C_assoc
IPR018201 Ketoacyl_synth_AS
IPR014031 Ketoacyl_synth_C
IPR014030 Ketoacyl_synth_N
IPR016036 Malonyl_transacylase_ACP-bd
IPR036291 NAD(P)-bd_dom_sf
IPR020801 PKS_acyl_transferase
IPR020841 PKS_Beta-ketoAc_synthase_dom
IPR020807 PKS_dehydratase
IPR042104 PKS_dehydratase_sf
IPR020843 PKS_ER
IPR013968 PKS_KR
IPR020806 PKS_PP-bd
IPR015083 Polyketide_synth_docking
IPR009081 PP-bd_ACP
IPR006162 Ppantetheine_attach_site
IPR016039 Thiolase-like

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00698 Acyl_transf_1, 4 hits
PF08240 ADH_N, 1 hit
PF08990 Docking, 1 hit
PF16197 KAsynt_C_assoc, 3 hits
PF00109 ketoacyl-synt, 4 hits
PF02801 Ketoacyl-synt_C, 4 hits
PF08659 KR, 3 hits
PF00550 PP-binding, 4 hits
PF14765 PS-DH, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00827 PKS_AT, 4 hits
SM00826 PKS_DH, 3 hits
SM00829 PKS_ER, 2 hits
SM00825 PKS_KS, 4 hits
SM00823 PKS_PP, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47336 SSF47336, 4 hits
SSF50129 SSF50129, 2 hits
SSF51735 SSF51735, 8 hits
SSF52151 SSF52151, 4 hits
SSF53901 SSF53901, 4 hits
SSF55048 SSF55048, 4 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00606 B_KETOACYL_SYNTHASE, 4 hits
PS50075 CARRIER, 4 hits
PS00012 PHOSPHOPANTETHEINE, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P95814-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPEQDKTVEY LRWATTELQR TRAELAAHSE PLAIVGMACR LPGGVASPDD
60 70 80 90 100
LWRLLESGGD GIGAFPADRG WETGADGRGG FLTGAAGFDA GFFGVSPREA
110 120 130 140 150
LAMDPQQRVV LETSWEALEH AGIDPRSLNG SDTGVFLGAF FQGYGIGADF
160 170 180 190 200
DGYGTTSIHT SVLSGRLSYF YGLEGPAVTV DTACSSSLVA LHQAGQSLRT
210 220 230 240 250
GECSLALVGG VTVMASPAGF ADFSEQGGLA SDGRCKAFAE AADGTAFAEG
260 270 280 290 300
SGVLVVERLS DAERHGHRVL AVVRGSAVNQ DGASNGLSAP NGPSQERVIR
310 320 330 340 350
QALAHAGLQP SDVDAVEAHG TGTRLGDPIE ATALLATYGQ DRATPLLLGS
360 370 380 390 400
LKSNIGHTQA AAGVAGIIKM VLAMRHGTLP PTLHVDTPSS HVDWTTGDVE
410 420 430 440 450
LLTQARPWPQ TNRPHRAGIS SFGVSGTNAH VIIESHPRPT PAPDTGSSTH
460 470 480 490 500
PVPLLISART PEALDEHTTR IRAFLDDNPG ADRVTVAQTL ARRTPFEHRA
510 520 530 540 550
VLLGDTLITA DPNAGSGPVV FVYSGQSTLH PHTGHQLAAT YSVFADAWGE
560 570 580 590 600
VLGHLNADQG PATHFAHQIA LTALLRSWGI TPHAVIGHSL GEISAACAAG
610 620 630 640 650
VLSIGDASAL LAARSRLMDE LPTGGAMVTV LTSEENALRA LRPGVEIAAV
660 670 680 690 700
NGPHSVVLSG DEGPVLDVAQ QLGIHHRLPT RHAGHSARMD PLVAPLLEAA
710 720 730 740 750
SGLTYHQPHT AIPEDPTTAA YWARQVRDQV RFQAHAERYP GATFLEIGPN
760 770 780 790 800
QDLSPVVDGI PTQTGTPEEV QALHTALARL HTRGGVVDWP TVLGSDRAPV
810 820 830 840 850
ALPTYPFQHK DYWLRATAQV DVTGAGQEKV AHPLLGAAVA LPGTGGTVLT
860 870 880 890 900
GRVSLASHPW LGGHAVNGTV LLPGAAFLEL AVRAGDETGS DLLHELVVET
910 920 930 940 950
PLTLPATGSV AISVEVAEPD DTGRRAVTVH ARADGAALWT RHATGFLGKA
960 970 980 990 1000
AATTAETGDP APWPPAGARQ VDVGDVYERF AGIGYAYGSS FQGLLAAWRD
1010 1020 1030 1040 1050
GDTVHAEVAL PDEQVPDAAR FTLHPALLDA AFQAGALSAL DAPGEAARLP
1060 1070 1080 1090 1100
FSFQDVRIHA AGATRARVTV SRDGDRSTVR MTGEDGQPVA EVGSVVSRPY
1110 1120 1130 1140 1150
AGGSGSDDEL LRPVWTELPM PAPSAADPRV EVLDADPLDG EPAAATRELT
1160 1170 1180 1190 1200
ARVLDSLQHR LSATDDVTLV VRIGTGLAAA ATAGLVRSAQ AENPGRFVLV
1210 1220 1230 1240 1250
EAPPDTPADL LTACAALDEP QLAVRDGVLF APRLVRMSDP VHGPLPLPDG
1260 1270 1280 1290 1300
DWLLAHSASG VLQDVTLAAD GTPRRALEAG EVRVDVRAAG LNFRDVLIAL
1310 1320 1330 1340 1350
GTYDGATALG GEAAGVVVET GPGVADLAPG DRVFGLTRGG IGPTAVTDRR
1360 1370 1380 1390 1400
WLARIPDGWT FATAASVPIA FATAWYGLVD LAGLRAGEKV LVHAATGGVA
1410 1420 1430 1440 1450
MAATQVARHL GAEVYATAGT GKQHVLRAAG LPGTHVADSR TTAFRTDFPR
1460 1470 1480 1490 1500
MDVVLNSLTG EFIDASLELL DADGRFVEMG RAELRDPATI APAYLPFDLL
1510 1520 1530 1540 1550
DAGTDRIGEI LGELLRLFDA GALTPLPVRA WDIRQARDAL GVMSRARHIG
1560 1570 1580 1590 1600
KNVLTLPRPL DPEGAIVITG GSGTLAGILA RHVSAQHVYL LSRSAPPEGT
1610 1620 1630 1640 1650
PGIHLPCDVS DRQQLAAALR RIDRPITAVV HTAGALDDGT LPSLTPGRFD
1660 1670 1680 1690 1700
TELRPKADGA WHLHELTKDQ DLAAFVLYSS AAGVLGNAGQ GNYAAANAFL
1710 1720 1730 1740 1750
DALAEQRRAA GLPALSIAWG LWEDASGLTA ELSEADRQRM RRSGFRTITA
1760 1770 1780 1790 1800
RQGMRLYEAA RRTGSPVVVA AALDDAPDVP LLRGLRRTTV RRAAVRERSL
1810 1820 1830 1840 1850
ADRSPCCPTT SAPTPPSRSS WNSTATVLGH LGAEDIPATT TFKELGIDSL
1860 1870 1880 1890 1900
TAVQLRNALT TATGVRLNAT AVFDFPTPRA LAARLGDELA GTRAPVAART
1910 1920 1930 1940 1950
AATAAAHDEP LAIVGMACRL PGGVASPQEL WRLVASGTDA ITEFPADRGW
1960 1970 1980 1990 2000
DVDALYDPDP DAIGKTFVRH GGFLDGATGF DAAFFGISPR EALAMDPQQR
2010 2020 2030 2040 2050
VLLETSWEAF ESAGITPDAA RGSDTGVFIG AFSYGYGTGA DTNGFGATGS
2060 2070 2080 2090 2100
QTSVLSGRLS YFYGLEGPSV TVDTACSSSL VALHQAGQSL RSGECSLALV
2110 2120 2130 2140 2150
GGVTVMASPG GFVEFSRQRG LAPDGRAKAF GAGADGTSFA EGAGALVVER
2160 2170 2180 2190 2200
LSDAERHGHT VLALVRGSAA NSDGASNGLS APNGPSQERV IHQALANAKL
2210 2220 2230 2240 2250
TPADVDAVEA HGTGTRLGDP IEAQALLATY GQDRATPLLL GSLKSNIGHA
2260 2270 2280 2290 2300
QAASGVAGII KMVQAIRHGE LPPTLHADEP SPHVDWTAGA VELLTSARPW
2310 2320 2330 2340 2350
PGTGRPRRAA VSSFGVSGTN AHIILEAGPV KTGPVEAGAI EAGPVEVGPV
2360 2370 2380 2390 2400
EAGPLPAAPP SAPGEDLPLL VSARSPEALD EQIGRLRAYL DTGPGVDRAA
2410 2420 2430 2440 2450
VAQTLARRTH FTHRAVLLGD TVIGAPPADQ ADELVFVYSG QGTQHPAMGE
2460 2470 2480 2490 2500
QLAAAFPVFA DAWHDALRRL DDPDPHDPTR SQHTLFAHQA AFTALLRSWD
2510 2520 2530 2540 2550
ITPHAVIGHS LGEITAAYAA GILSLDDACT LITTRARLMH TLPPPGAMVT
2560 2570 2580 2590 2600
VLTSEEEARQ ALRPGVEIAA VFGPHSVVLS GDEDAVLDVA QRLGIHHRLP
2610 2620 2630 2640 2650
APHAGHSAHM EPVAAELLAT TRELRYDRPH TAIPNDPTTA EYWAEQVRNP
2660 2670 2680 2690 2700
VLFHAHTQRY PDAVFVEIGP GQDLSPLVDG IALQNGTADE VHALHTALAR
2710 2720 2730 2740 2750
LFTRGATLDW SRILGGASRH DPDVPSYAFQ RRPYWIESAP PATADSGHPV
2760 2770 2780 2790 2800
LGTGVAVAGS PGRVFTGPVP AGADRAVFIA ELALAAADAT DCATVEQLDV
2810 2820 2830 2840 2850
TSVPGGSARG RATAQTWVDE PAADGRRRFT VHTRVGDAPW TLHAEGVLRP
2860 2870 2880 2890 2900
GRVPQPEAVD TAWPPPGAVP ADGLPGAWRR ADQVFVEAEV DSPDGFVAHP
2910 2920 2930 2940 2950
DLLDAVFSAV GDGSRQPTGW RDLAVHASDA TVLRACLTRR DSGVVELAAF
2960 2970 2980 2990 3000
DGAGMPVLTA ESVTLGEVAS AGGSDESDGL LRLEWLPVAE AHYDGADELP
3010 3020 3030 3040 3050
EGYTLITATH PDDPDDPTNP HNTPTRTHTQ TTRVLTALQH HLITTNHTLI
3060 3070 3080 3090 3100
VHTTTDPPGA AVTGLTRTAQ NEHPGRIHLI ETHHPHTPLP LTQLTTLHQP
3110 3120 3130 3140 3150
HLRLTNNTLH TPHLTPITTH HNTTTTTPNT PPLNPNHAIL ITGGSGTLAG
3160 3170 3180 3190 3200
ILARHLNHPH TYLLSRTPPP PTTPGTHIPC DLTDPTQITQ ALTHIPQPLT
3210 3220 3230 3240 3250
GIFHTAATLD DATLTNLTPQ HLTTTLQPKA DAAWHLHHHT QNQPLTHFVL
3260 3270 3280 3290 3300
YSSAAATLGS PGQANYAAAN AFLDALATHR HTQGQPATTI AWGMWHTTTT
3310 3320 3330 3340 3350
LTSQLTDSDR DRIRRGGFLP ISDDEGMRLY DAAVGSGEDF VLAAAMDPAQ
3360 3370 3380 3390 3400
PMAGDVPPIL SGLRKSARRT ARTGQTFAQR LAELPAADRD TALVTLVSDA
3410 3420 3430 3440 3450
TAAVLGHADA SGIAPTTTFK DLGIDSLTAI ELRNRLAEAT GLRLSATMVF
3460 3470 3480 3490 3500
DHPTPRVLAA ELRTDLFGTA APLPARTART RHDEPLAIVG MACRLPGGVT
3510 3520 3530 3540 3550
SPEDLWRLVA SGTDAITEFP TDRGWDIDRM FDPDPDAPGK TYVRHGGFLS
3560 3570 3580 3590 3600
EAAGFDAAFF GISPREAWAM DPQQRVILET VWEAFENAGI VPDTLRGSDT
3610 3620 3630 3640 3650
GVFMGAFSHG YGAGDDLGGF GATATQNSVL SGRLSYFFGM EGPAVTIDTA
3660 3670 3680 3690 3700
CSSSMVALHQ AAQSLRDGEC SLALAGGVTV MPTPLGYVEF CRQRGLAPDG
3710 3720 3730 3740 3750
RAKAFAEGAD GTSFSEGAGV LVVERLSDAE RNGHTVLALV RSSAVNQDGA
3760 3770 3780 3790 3800
SNGISAPNGP SQQRVIRQAL DKAGLAPADV DVVEAHGTGT PLGDPIEAQA
3810 3820 3830 3840 3850
IIATYGQDRD TPLYLGSVKS NIGHTQTTAG LAGVIKMVMA MRHGLLPKTL
3860 3870 3880 3890 3900
HVDEPSSHVD WSAGAVELLT EARPWPDSDR PRRAGVSSLG ISGTNAHVIL
3910 3920 3930 3940 3950
EGVAESSVRS VESSGLVPLP VSARTESSLA LQVERLGEYV RGARDLAAVA
3960 3970 3980 3990 4000
DGLVRGRTVF GHRAVLLGES TVAGVAGAES RTVFVFPGQG SQWVGMGREL
4010 4020 4030 4040 4050
MGCSEVFAAR MRECAAVLEP YTGWDLLDVL GEAVVAERVE VLQPASWAVA
4060 4070 4080 4090 4100
VSLAALWQAH GVSPDAVIGH SQGEIAAACV AGALSLEDAA RIVALRSQTI
4110 4120 4130 4140 4150
AAHLAGRGAM ASIALPATAV ETVEGVWVAA RNGPESTVVA GDPSAVERVL
4160 4170 4180 4190 4200
ARYEAEGVRV RRIAVDYASH TPHVEAIQEQ LADVLGDITS SAPSVPWWST
4210 4220 4230 4240 4250
VDGGWVTEPA GDDYWYRNLR QPVAMDTAIG ELDGSLFIEC SAHPVLLPAL
4260 4270 4280 4290 4300
DQERTVASLR TDDGGWDRFL TALAQAWTQG ADVDWTTLIA PAPDRLLDLP
4310 4320 4330 4340 4350
TYPFDHKRYW IEATGAADLT ALGLTDTAHP MLAATAALPT NDGTVLTGRI
4360 4370 4380 4390 4400
SLRTHPWLAD HTIQDTVLLP GTAFLELVMR AGDEVGCDTI DELVIETPLT
4410 4420 4430 4440 4450
LPVTGAVDLT VTVEQADATG HRPVSVHARP AGTDTWTRHA TGTLGRTEDT
4460 4470 4480 4490 4500
APDTNSFPQW PPTGPTALDV TEFYAQLAAL GYRFVPTFRG LRAAWRAGDT
4510 4520 4530 4540 4550
VYAEVALPED RAADADHFGV HPALLDAALQ SGSLLMLESD GEQGVQLPFS
4560 4570 4580 4590 4600
WHGVRFHATG ATSLRVAIVP GPDGLRLRAA DSENHPVATI DALVTRPPAD
4610 4620 4630 4640 4650
LAPSDPVLRV GWTAVPVPAE VRPSDADVLM LHSDDADPIQ ETRDLTTRVL
4660 4670 4680 4690 4700
DALLTTEGTL IVQVTGGLAA MAAAGLVRTA QSEQPGRFFL VETDPGEVLD
4710 4720 4730 4740 4750
GARCDMIAAL GEPRLRLRGN RFEAARLVRA AAALTPPDTG SWQLRQSATG
4760 4770 4780 4790 4800
SLDDVAIVPT GEPDRPLGAG EVRIAVRAAG LNFRDDTVAL GVVADDRPLG
4810 4820 4830 4840 4850
SEAAGVVLET GPGVHDLAPG DRVLGMLAGA FGPVAITDRR LLGRMPDGWT
4860 4870 4880 4890 4900
FPQAASVVTV FATTWYGLVD LAELRPGEKV LIHAAATGVG AAAVQIARHL
4910 4920 4930 4940 4950
DADVYATAST PKQHLLDLEP THIADSRTTA FADTFPPADV VLNSLTGPLL
4960 4970 4980 4990 5000
DASAQLLTPG GRFIEMGKTD IRHHVQQPFD LMVAGPDRLQ QIITQLLDLF
5010 5020 5030 5040 5050
ANGTLHPLPV HAWDVRQARE AFGWMSSGRH TGKLVLTVPR PLDPEGAVII
5060 5070 5080 5090 5100
TGGSGTLAGH LARHLDHPHT YLLSRTPPPD TTPGTHLPCD VSDPTQLATA
5110 5120 5130 5140 5150
LAQIPQPLTG IFHTAATLDD ALLHNLTPQR IDTVLQPKAD AAWHLHHHTH
5160 5170 5180 5190 5200
THATDLAAFV LYSAVAGVMG SPGQGNYVAA NAFLDALAEH RQAMGLPAQS
5210 5220 5230 5240 5250
LAWGMWADVS ALTAKLTDAD RGRIRRGGFP PLSAADGMRL FDSAARTRSR
5260 5270 5280 5290 5300
SSSRRPSDVT RLDGPVAPLL RGLVAHRSGP VRAVARNADD EPLAARLAGH
5310 5320 5330 5340 5350
TAAEQRRVMQ EVVLRQAAAV LAYGLGEQVA ADRPFRDLGF DSLTAVDLRN
5360 5370 5380 5390 5400
RLAAETGLRL PTTVVFSHPT AEALATHLLE LLDAPAALTT GAPLPAVTAA
5410 5420 5430 5440 5450
PGTAARDQDE PIAIVAMACR LPGGVTSPEE LWRLVESGTD AITTAPGDRG
5460 5470 5480 5490 5500
WDLDALYDPD PDAVGKAYSL RGGFLEGAAE FDAAFFDISP RESLGMDPQQ
5510 5520 5530 5540 5550
RLLLETAWEA IERGRINPAS LHGREIGVYV GAAAQGYGLG AEDTEGNAIT
5560 5570 5580 5590 5600
GGSTSLLSGR LAYVLGLEGP AVTVDTACSS SLVALHLACQ GLRLGECELA
5610 5620 5630 5640 5650
LAGGVSVLSS PAAFVEFSRQ RGLAADGRCK SFGSGADGTT WAEGVGVLVL
5660 5670 5680 5690 5700
EQLSDAERLG HTVLAVVRGS AVTSDGASNG LTAPNGLAQQ RVIRKALAAA
5710 5720 5730 5740 5750
GLTAADVDLV EGHGTGTRLG DPVEADALLA TYGQNRGEPV WLGSLKSNIG
5760 5770 5780 5790 5800
HATAAAGVAG VIKTVQAIGA GTMPRTLHAD EPSPAVDWTA GQVSLLTGNR
5810 5820 5830 5840 5850
PWPMTSVPGE RPSPRSGSAG RTLTSSLNST VRSPWRRDRL ARNPGRCLGC
5860 5870 5880 5890 5900
CPRGPLPPCG RRPPVCAIIW RPSGPDPLDI GYAQATSRAQ FTHRAAEEAA
5910 5920 5930 5940 5950
SPDGFRAGLD SVADGAEAPE SSAEPPRSAR RFLFDGQGAQ RVGMGRELHG
5960 5970 5980 5990 6000
RFPVFAAAWD EVSDAFGKHL EHSPTDVFHG EHGDLAHDTL YAQVGLFTLE
6010 6020 6030 6040 6050
VALLRLLEHW GVRPDVVVGH SVGEVTAAYA AGVLTLADAT TLIVARGRAL
6060 6070 6080 6090 6100
RALPPGAMTA VEGSPAEVGA FTDLDIAAVN GPSAVVLTGA PDDVAAFERE
6110 6120 6130 6140 6150
WAAAGRRAKR LDVGHAFHSR HVDGALDDFR GVLESLAFGA ARLPVVSTTT
6160 6170 6180 6190 6200
GRDAAGDLAT PEHWLRHARR PVLYADAVRE LADLGVNMFV AVGPSGALAS
6210 6220 6230 6240 6250
AASENTGGSA GTYHAVLRAR TGEESAALTA VAELHAHGAP VDLAAVLAGG
6260 6270 6280 6290 6300
RPVDLPVYPF QHRSYWLAPA VGGGSPTAVP DTGRPTEPDP DDLTVAEIVR
6310 6320 6330 6340 6350
RRAAALLGIA DPGDVDADTT FFALGFDSLA VQRLRNQLTA ATGLDLPTAV
6360 6370 6380 6390 6400
LFDHDTPSAL TAYLEEQLGD GADDDAPTVL ALLAEMDSLD AADTAATPAP
6410 6420
ERAAIADLLD KLSRTWKDHR
Length:6,420
Mass (Da):672,230
Last modified:July 1, 1997 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i25BCD2069456BEF1
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
Y10438 Genomic DNA Translation: CAA71463.1

Genome annotation databases

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
ag:CAA71463

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y10438 Genomic DNA Translation: CAA71463.1

3D structure databases

Database of comparative protein structure models

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ModBasei
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SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

KEGGiag:CAA71463

Phylogenomic databases

KOiK16377

Family and domain databases

Gene3Di1.10.1200.10, 4 hits
3.10.129.110, 3 hits
3.40.366.10, 4 hits
3.40.47.10, 4 hits
InterProiView protein in InterPro
IPR001227 Ac_transferase_dom_sf
IPR036736 ACP-like_sf
IPR014043 Acyl_transferase
IPR016035 Acyl_Trfase/lysoPLipase
IPR013154 ADH_N
IPR011032 GroES-like_sf
IPR032821 KAsynt_C_assoc
IPR018201 Ketoacyl_synth_AS
IPR014031 Ketoacyl_synth_C
IPR014030 Ketoacyl_synth_N
IPR016036 Malonyl_transacylase_ACP-bd
IPR036291 NAD(P)-bd_dom_sf
IPR020801 PKS_acyl_transferase
IPR020841 PKS_Beta-ketoAc_synthase_dom
IPR020807 PKS_dehydratase
IPR042104 PKS_dehydratase_sf
IPR020843 PKS_ER
IPR013968 PKS_KR
IPR020806 PKS_PP-bd
IPR015083 Polyketide_synth_docking
IPR009081 PP-bd_ACP
IPR006162 Ppantetheine_attach_site
IPR016039 Thiolase-like
PfamiView protein in Pfam
PF00698 Acyl_transf_1, 4 hits
PF08240 ADH_N, 1 hit
PF08990 Docking, 1 hit
PF16197 KAsynt_C_assoc, 3 hits
PF00109 ketoacyl-synt, 4 hits
PF02801 Ketoacyl-synt_C, 4 hits
PF08659 KR, 3 hits
PF00550 PP-binding, 4 hits
PF14765 PS-DH, 2 hits
SMARTiView protein in SMART
SM00827 PKS_AT, 4 hits
SM00826 PKS_DH, 3 hits
SM00829 PKS_ER, 2 hits
SM00825 PKS_KS, 4 hits
SM00823 PKS_PP, 4 hits
SUPFAMiSSF47336 SSF47336, 4 hits
SSF50129 SSF50129, 2 hits
SSF51735 SSF51735, 8 hits
SSF52151 SSF52151, 4 hits
SSF53901 SSF53901, 4 hits
SSF55048 SSF55048, 4 hits
PROSITEiView protein in PROSITE
PS00606 B_KETOACYL_SYNTHASE, 4 hits
PS50075 CARRIER, 4 hits
PS00012 PHOSPHOPANTETHEINE, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiP95814_STRSQ
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P95814
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: July 1, 1997
Last modified: December 11, 2019
This is version 119 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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