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Protein

Glycine--tRNA ligase alpha subunit

Gene

glyQ

Organism
Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCBUR227377:G1G0B-1885-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glycine--tRNA ligase alpha subunit (EC:6.1.1.14)
Alternative name(s):
Glycyl-tRNA synthetase alpha subunit
Short name:
GlyRS
Gene namesi
Name:glyQ
Ordered Locus Names:CBU_1913
OrganismiCoxiella burnetii (strain RSA 493 / Nine Mile phase I)
Taxonomic identifieri227377 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella
Proteomesi
  • UP000002671 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000728351 – 319Glycine--tRNA ligase alpha subunitAdd BLAST319

Interactioni

Subunit structurei

Tetramer of two alpha and two beta subunits.By similarity

Protein-protein interaction databases

STRINGi227377.CBU_1913

Structurei

3D structure databases

ProteinModelPortaliP94616
SMRiP94616
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi301 – 305Poly-Ser5

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4107QIB Bacteria
COG0752 LUCA
HOGENOMiHOG000264291
KOiK01878
OMAiLGSYYQF

Family and domain databases

CDDicd00733 GlyRS_alpha_core, 1 hit
HAMAPiMF_00254 Gly_tRNA_synth_alpha, 1 hit
InterProiView protein in InterPro
IPR006194 Gly-tRNA-synth_heterodimer
IPR002310 Gly-tRNA_ligase_asu
PANTHERiPTHR44629 PTHR44629, 1 hit
PfamiView protein in Pfam
PF02091 tRNA-synt_2e, 1 hit
PRINTSiPR01044 TRNASYNTHGA
TIGRFAMsiTIGR00388 glyQ, 1 hit
PROSITEiView protein in PROSITE
PS50861 AA_TRNA_LIGASE_II_GLYAB, 1 hit

Sequencei

Sequence statusi: Complete.

P94616-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSSHPVNFQ QMILALQEYW ASQGCVLLQP FDMEVGAGTF HPATFLRAIG
60 70 80 90 100
PEPWRAAYVQ PSRRPTDGRY GDNPNRTQHY YQFQVVLKPS PDDIQDIYLG
110 120 130 140 150
SLKALGIDPL THDIRFVEDN WEAPTLGSWG VGWEVWQDGM EITQFTYFQQ
160 170 180 190 200
IGGLECKPVT GEITYGLERL AMFLQGIDNM FDLVWTEGPN GRVTYGQIFQ
210 220 230 240 250
QNEVEMSAYN FEYANVEALF NFFDFYEKEA SQLIEVHLPL AAYEMVLKAS
260 270 280 290 300
HTFNLLDARQ AISVTERQRF ILRVRKLAQA VAEAYYSARE KLGFPMLEEI
310
SSSSSRVLPL AGNDRVKGC
Length:319
Mass (Da):36,397
Last modified:May 1, 1997 - v1
Checksum:iFF52579A9F0787F8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y10435 Genomic DNA Translation: CAA71456.1
AE016828 Genomic DNA Translation: AAO91404.1
RefSeqiNP_820890.1, NC_002971.3
WP_005769976.1, NZ_LM994641.1

Genome annotation databases

EnsemblBacteriaiAAO91404; AAO91404; CBU_1913
GeneIDi1209826
31482848
KEGGicbu:CBU_1913
PATRICifig|227377.7.peg.1897

Similar proteinsi

Entry informationi

Entry nameiSYGA_COXBU
AccessioniPrimary (citable) accession number: P94616
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 1997
Last modified: February 28, 2018
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. Coxiella burnetii
    Coxiella burnetii (strain RSA 493): entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

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